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Synthesis, Characterization and Phyto-Function of Nanophotocatalysts

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry and Chemical Physics".

Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 4375

Special Issue Editors


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Guest Editor
1. CQE, Centro de Química Estrutural, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
2. LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal
Interests: tetrapyrrolic macrocycles; corroles; porphyrins; carbon nanomaterials; fluorescent probes; photodynamic therapy

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Guest Editor
LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: organic chemistry; N-heterocycles; tetrapyrroles; photodynamic applications; photosensitizers; antimicrobial; antitumoral; supramolecular chemistry; chemosensing; remediation
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Special Issue Information

Dear Colleagues, 

The development of efficient and stable photocatalysts is of crucial importance in modern science considering the strong dependence of industry and laboratories on nonrenewable energy and the dramatic increase in atmospheric CO2 concentration. Using light energy to promote chemical reactions is a particularly relevant solution due to the sustainability of solar energy. Critical to this process is the catalyst, as well as the possibility of scaling down bulk photocatalysts to the nanoscale, with controlled properties at molecular level. Advances in these areas are expanding the practical applicability of nanophotocatalyts in different contexts (e.g., organic synthesis; water splitting to generate hydrogen fuel; degradation of pollutants/dyes; inactivation of cancer cells and microorganisms). Another challenge is represented by the replacement of conventional synthetic approaches using potentially hazardous reagents to prepare nanophotocatalysts via recycling waste biomass and crude biogenic materials such as plant extracts (e.g., leaves, roots, flowers and peels) and biological derivatives. These phytochemicals are used not only as reducing and stabilizing agents in nanoparticle synthesis but also have an important role in controlling the size, dispersibility and shape of the nanoparticles.

This Special Issue aims to offer a forum for the publication of original research/review articles on the synthesis and characterization of nanophotocatalysts using phytochemicals, and their potential applications.

Articles can cover (but are not limited to) the following topics:

  • Development and characterization of nanophotocatalysts using green approaches and biogenic routes;
  • Exploring their efficiency in organic synthesis;
  • Hydrogen production via water splitting;
  • Dissociation of volatile organic pollutants and air purification (VOC or NOx removal);
  • Degradation of dyes/pollutants (pesticides, pharmaceutics, emerging contaminants); 
  • Transformation of carbon dioxide into valuable energy-related chemicals;
  • Inactivation of cancer cells and microorganisms, among others.

Prof. Dr. Maria G. P. M. S. Neves
Dr. Carla Isabel Madeira dos Santos
Dr. Nuno M. M. Moura
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanophotocatalysts
  • green synthesis
  • hydrogen generation
  • pollutants
  • fine chemistry
  • photoinactivation
  • cancer
  • microorganisms

Published Papers (2 papers)

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Research

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19 pages, 6944 KiB  
Article
Efficient Strategies to Use β-Cationic Porphyrin-Imidazolium Derivatives in the Photoinactivation of Methicillin-Resistant Staphylococcus aureus
by Nuno M. M. Moura, Xavier Moreira, Eliana Sousa Da Silva, Joaquim Luís Faria, Maria G. P. M. S. Neves, Adelaide Almeida, Maria A. F. Faustino and Ana T. P. C. Gomes
Int. J. Mol. Sci. 2023, 24(21), 15970; https://doi.org/10.3390/ijms242115970 - 04 Nov 2023
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Abstract
Bacterial resistance to antibiotics is a critical global health issue and the development of alternatives to conventional antibiotics is of the upmost relevance. Antimicrobial photodynamic therapy (aPDT) is considered a promising and innovative approach for the photoinactivation of microorganisms, particularly in cases where [...] Read more.
Bacterial resistance to antibiotics is a critical global health issue and the development of alternatives to conventional antibiotics is of the upmost relevance. Antimicrobial photodynamic therapy (aPDT) is considered a promising and innovative approach for the photoinactivation of microorganisms, particularly in cases where traditional antibiotics may be less effective due to resistance or other limitations. In this study, two β-modified monocharged porphyrin-imidazolium derivatives were efficiently incorporated into polyvinylpyrrolidone (PVP) formulations and supported into graphitic carbon nitride materials. Both porphyrin-imidazolium derivatives displayed remarkable photostability and the ability to generate cytotoxic singlet oxygen. These properties, which have an important impact on achieving an efficient photodynamic effect, were not compromised after incorporation/immobilization. The prepared PVP-porphyrin formulations and the graphitic carbon nitride-based materials displayed excellent performance as photosensitizers to photoinactivate methicillin-resistant Staphylococcus aureus (MRSA) (99.9999% of bacteria) throughout the antimicrobial photodynamic therapy. In each matrix, the most rapid action against S. aureus was observed when using PS 2. The PVP-2 formulation needed 10 min of exposure to white light at 5.0 µm, while the graphitic carbon nitride hybrid GCNM-2 required 20 min at 25.0 µm to achieve a similar level of response. These findings suggest the potential of graphitic carbon nitride-porphyrinic hybrids to be used in the environmental or clinical fields, avoiding the use of organic solvents, and might allow for their recovery after treatment, improving their applicability for bacteria photoinactivation. Full article
(This article belongs to the Special Issue Synthesis, Characterization and Phyto-Function of Nanophotocatalysts)
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Review

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42 pages, 15844 KiB  
Review
Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review
by Carlos J. P. Monteiro, Maria G. P. M. S. Neves, Cristina Nativi, Adelaide Almeida and Maria Amparo F. Faustino
Int. J. Mol. Sci. 2023, 24(4), 3475; https://doi.org/10.3390/ijms24043475 - 09 Feb 2023
Cited by 6 | Viewed by 3035
Abstract
Cellulose is the most abundant natural biopolymer and owing to its compatibility with biological tissues, it is considered a versatile starting material for developing new and sustainable materials from renewable resources. With the advent of drug-resistance among pathogenic microorganisms, recent strategies have focused [...] Read more.
Cellulose is the most abundant natural biopolymer and owing to its compatibility with biological tissues, it is considered a versatile starting material for developing new and sustainable materials from renewable resources. With the advent of drug-resistance among pathogenic microorganisms, recent strategies have focused on the development of novel treatment options and alternative antimicrobial therapies, such as antimicrobial photodynamic therapy (aPDT). This approach encompasses the combination of photoactive dyes and harmless visible light, in the presence of dioxygen, to produce reactive oxygen species that can selectively kill microorganisms. Photosensitizers for aPDT can be adsorbed, entrapped, or linked to cellulose-like supports, providing an increase in the surface area, with improved mechanical strength, barrier, and antimicrobial properties, paving the way to new applications, such as wound disinfection, sterilization of medical materials and surfaces in different contexts (industrial, household and hospital), or prevention of microbial contamination in packaged food. This review will report the development of porphyrinic photosensitizers supported on cellulose/cellulose derivative materials to achieve effective photoinactivation. A brief overview of the efficiency of cellulose based photoactive dyes for cancer, using photodynamic therapy (PDT), will be also discussed. Particular attention will be devoted to the synthetic routes behind the preparation of the photosensitizer-cellulose functional materials. Full article
(This article belongs to the Special Issue Synthesis, Characterization and Phyto-Function of Nanophotocatalysts)
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