Recent Advances and Techniques for the Vascularization of Tissue Engineering Constructs
Deadline for manuscript submissions: 20 April 2024 | Viewed by 1259
Interests: scaffold free tissue engineering; vascularization; stem cells; regenerative medicine; animal models
Interests: tissue engineering; regenerative medicine; biomaterials; biomimetics; biodegradable materials; 3D in vitro models; cancer modelling
Special Issues, Collections and Topics in MDPI journals
Vascularization is a critical step when engineering functional tissue constructs. To ensure adequate perfusion of thick engineered tissues after transplantation is essential to allow not only their survival but also their intended function and, ultimately, integration with the host tissue. Many strategies have been put forward to overcome this problem. In vitro prevascularization is by far the most explored strategy but issues related with cell sourcing and potential regression of the prevascular network remain. This collection intends to bring into view the latest developments related with vascularization in the Tissue Engineering field. Specifically, developments regarding the use and disclosure of novel cell populations that can contribute to the angiogenic and vasculogenic processes towards the improved vascularization of Tissue Engineered constructs, scaffold-based or scaffold-free, is of interest. Additionally, the use of innovative biomaterials or molecules that can specifically target and promote angiogenesis, vasculogenesis or vessel ingrowth into Tissue Engineering constructs is also of interest. Finally, the application of advanced techniques to study the vascularization process based on, for instance, microfluidics or the establishment of vascular beds will also be appreciated.
Research articles, review articles as well as communications are invited.
Dr. Rogério P. Pirraco
Prof. Dr. Rui L. Reis
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- tissue engineering