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Epigenetic Modifications in Health and Disease

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 257

Special Issue Editor

E-Mail Website
Guest Editor
Animal and Comparative Biomedical Sciences and Bio5 Research Institute, The University of Arizona, Tucson, AZ, USA
Interests: fetal development; epigenetics; long non-coding RNA; cardiovascular biology; cerebral autoregulation

Special Issue Information

Dear Colleagues,

Accumulating evidence suggests that epigenetic modifications play a crucial role in chronic disorders such as diabetes mellitus, obesity, and hypertension. Importantly, maternal exposure to different stressors can change the epigenetic landscape of the fetal genome and adversely impact the risk of such disorders in adult life. Among various epigenetic modifications, DNA methylation has emerged as an important regulator of transcription and long-term control of gene expression. Moreover, evidence supports that DNA modification is heritable and alters the health and disease risk for the next few generations.

In this Special Issue of IJMS, we will focus on DNA methylation and its role in metabolic syndrome (hypertension, obesity, and diabetes mellitus). The aim of this Special Issue will be to provide a comprehensive update on the role of DNA methylation in hypertension, obesity, and/or diabetes mellitus. We welcome original research articles and up-to-date review articles.

Dr. Ravi Goyal
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • proximal promoter methylation
  • CpG islands
  • Dohad
  • fetal programming
  • fetal origins of adult disorders
  • developmental origins of health and disease

Published Papers

This special issue is now open for submission.
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