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Special Issue "Cultivated Plants and Tissue Cultures: The Cellular and Biological Bases Associated with Secondary Metabolism"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 155

Special Issue Editors

Technische Universität Braunschweig, 38106 Braunschweig, Germany
Interests: plant secondary metabolism; biosynthesis and biotechnology of polyprenylated aromatic polyketides; transgenesis; plant tissue culture; biosynthesis of benzoic acid-based phytoalexins such as xanthones and biphenyls
Special Issues, Collections and Topics in MDPI journals
Department of Life Sciences, University of Siena, 53100 Siena, Italy
Interests: physiological, biochemical, and molecular responses of plants to abiotic stresses such as deficiencies of natural resources (e.g., nutrients and water) or salinity; analysis of the effects of biofertilizers (i.e., biochar and wood distillate) on the soil–plant system; the use of solid and liquid byproducts of hydrothermal carbonization (HTC) in soilless culture systems; analysis of the impact of bioplastics on plant yield and soil quality
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the context of plant adaptation to the environment, secondary metabolites are a category of bioactive molecules. They are effective at low concentrations and are mainly used to define plant–environment interactions. They are often cell-, tissue- or organ-specific compounds, meaning they may be constitutively synthesized at low levels, but this may increase due to the impact stimuli such as growth regulators, abiotic or biotic stress conditions rather than developmental and seasonal phases. Changes in secondary metabolites (or natural plant products) can affect the colour, smell and taste of plants. These changes can have beneficial or harmful effects on human and animal health, opening frontiers for further pharmacological research. Formerly, the direct extraction of these bioactive molecules from plants suffered from low yields, high costs and seasonal fluctuation of the extracted component. Nowadays, tailored cultivation and tissue cultures are the in vivo and in vitro plant biotechnological tools that can be optimized to enhance the efficient production of desired plant secondary metabolites, allowing researchers to standardize the production levels of the target compounds compared to undesired ones. Furthermore, the genetic engineering of these cultures may support the biosynthesis of new-to-nature bioactive phytomedicines.

As such, we are eager to invite researchers to contribute work on topics in the field of plant biotechnology and secondary metabolism. This topic focuses on studying the molecular, biochemical, and phytochemical changes, following certain treatments of either cultivation- or tissue culture-based systems. We also welcome manuscripts concerning the integration of natural substances into the plant cultivation process, which can selectively increase the production of secondary metabolites, hence the important role in preserving human health. Both original research papers and up-to-date review articles are welcome.

Dr. Mariam Gaid
Dr. Silvia Celletti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • abiotic and biotic stressors
  • bioactive compounds
  • biopesticides
  • bioreactors
  • genetic engineering
  • metabolites
  • phytochemicals
  • phytohormones
  • phytomedicine
  • tailored tissue cultures

Published Papers

There is no accepted submissions to this special issue at this moment.
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