Special Issue "Biological Cues for Tissue Regeneration and Bioactive Materials"
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 8507
Interests: tissue regeneration; bioactive materials; cell delivery systems; nanostructured materials
Special Issues, Collections and Topics in MDPI journals
Regenerative medicine aims at restoring lost soft or hard tissues with functional ones. The challenge increases exponentially when the engineered tissue has to replace a large defect, be used in aseptic conditions, or to overcome a systemic disease. Nonetheless, understanding the biological cues of soft and hard tissue healing is crucial to design functionalized biomaterials which target the affected cue and ensure a functional healing in the mechanical and physiological sense. To achieve such functionality, tissue engineering and material science tools depend on: 1) creating similar structures to the lost tissue through a better three-dimensional design, 2) reflect the biological understanding of the tissue to deliver specific agents that would either enhance or reduce specific cellular activities or infections, 3) use cell therapy approaches to achieve functional healing, and finally 5) use combinations of some or even all options. The achievement brought by the innovation of biomaterials enhanced their biocompatibility, biodegradability, and structural similarity to the target tissue (bioinspired materials) to promote healing especially in challenged situations.
Delivery of nano and micro bioactive molecules has many methods as the supporting matrix directly, or binding to the material surface, or covalently linking cell adhesion molecules to the scaffold. Furthermore, nanotechnology enabled the structuring of novel biomaterials with customized mechanical and physiological properties to stimulate regeneration of soft and hard tissues.
The scope of this special issue aims to cover the understanding of biological cues in tissue regeneration, the fabrication of nanostructured biomaterials and bioactive materials potential to achieve recovery of tissue function.
Dr. Thaqif El Khassawna
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- tissue regeneration
- bioactive materials
- cell delivery systems
- nanostructured materials
- in vitro models