Single-Cell and Single-Molecule Analysis of Microorganism
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 9313
Interests: single molecule imaging of DNA, RNA, and protein; genome architecture of bacteria, archaea, and eukarya; biological application of atomic force microscopy
Special Issues, Collections and Topics in MDPI journals
Historically, molecular studies of replication, transcription and translation mechanisms of viruses and bacteria have established the foundation (principles and theories) of eukaryotic molecular biology. Recent developments of cell/molecular analytical technologies have paved the way for the identification of a variety of individual molecular and cellular events. Among them, single cell/molecular imaging and manipulation techniques have been contributing to a physicochemical as well as structural basis for our understanding of such events.
This Special Issue will focus upon Nanobiology of Viruses, Microbe, and Intracellular Organelles, with special attention to the structural basis of their activities such as cell cycle, dynamic intracellular structures with cytoskeletons, genome folding, and others. Investigations using single cell/molecular imaging and manipulation techniques combined with other analytical methods will showcase their power to elucidate key principles of folding and interaction of biological macromolecules. Furthermore, comparisons of the data obtained from these innovative approaches with data related to eukaryotic systems will provide insights into molecular and cell biology in general.
Prof. Dr. Kunio Takeyasu
Manuscript Submission Information
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- Single-molecule imaging
- Single-molecule manipulation
- Ultra resolution microscopy
- RNA virus genome
- DNA virus genome
- Genome structure
- Membrane structure