Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.8
5.6
Journals
IJMS
Special Issues
Adipokines as Peripheral Signals for the Integration of Energy Balance...
ijms-logo
Submit to Special Issue Submit Abstract to Special Issue Review for IJMS Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Adipokines as Peripheral Signals for the Integration of Energy Balance and Reproduction

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 1188

Special Issue Editors

Dr. Roberta Lattanzi

E-Mail Website
Guest Editor
Department of Physiology and Pharmacology “Vittorio Erspamer”, University Sapienza, I-00185 Rome, Italy
Interests: G protein-coupled receptor; chemokines; prokineticins; pain; neuroinflammation; in vivo and in vitro pharmacological analysis
Special Issues, Collections and Topics in MDPI journals
Dr. Rossella Miele

E-Mail Website
Guest Editor
Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185 Rome, Italy
Interests: G protein-coupled receptor; signal transduction; chemokines; protein-protein interactions; yeast genetic analysis; alternative splicing; transcriptional regulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In mammals, reproductive functions are known to be tightly regulated by energy availability. Atypical weight loss or gain (obesity) negatively affects the reproductive axis. The balance between energy homeostasis and reproduction is monitored by a complex system involving the brain and a variety of peripheral tissues. This process occurs via numerous factors, including metabolic hormones and nutrients.

The aim of this Special Issue is to review emerging aspects of the role of adipokines, endocrine factors secreted primarily by white adipose tissue, in the regulation of fertility and reproduction in health, obesity and reproductive disorders.

Dr. Roberta Lattanzi
Dr. Rossella Miele
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adipokines
  • obesity
  • fertility
  • reproduction
  • hypothalamic–pituitary–gonadal axis

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

13 pages, 2823 KiB  
Article
Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity
by Nari Kim, Yejin Ahn, Kayoung Ko, Boyun Kim, Kisoo Han, Hyung Joo Suh, Jewon Jung and Ki-Bae Hong
Int. J. Mol. Sci. 2023, 24(22), 16302; https://doi.org/10.3390/ijms242216302 - 14 Nov 2023
Viewed by 893
Abstract
The increasing frequency of processed food consumption has led to the higher ingestion of sugar, increasing the risk of chronic diseases, such as obesity. Yeast hydrolysates (YHs) inhibit body fat accumulation. However, the action mechanism of YH in relation to high-sugar diet-induced obesity [...] Read more.
The increasing frequency of processed food consumption has led to the higher ingestion of sugar, increasing the risk of chronic diseases, such as obesity. Yeast hydrolysates (YHs) inhibit body fat accumulation. However, the action mechanism of YH in relation to high-sugar diet-induced obesity is still unclear. Therefore, this study aimed to evaluate the biological effects of YH on lipid accumulation and verify behavioral changes and carbohydrate metabolic gene regulation in high-sugar diet-fed fruit flies. Adult male flies (Drosophila melanogaster; 2–5 days old) were exposed to 20% sucrose for obesity induction. In high-sugar-fed Drosophila, the effect of YH was compared with that of yeast extract. The effects of YH on body conditions and lipid droplet size were quantified and analyzed. Behavioral factors were evaluated by analyzing circadian rhythm patterns and neurotransmitter content, and a molecular approach was used to analyze the expression of metabolism-related genes. Dietary supplementation with YH did not reduce total sugar content, but significantly decreased the triglyceride (TG) levels in Drosophila. A behavioral analysis showed that the total number of night-time activities increased significantly with YH treatment in a dose-dependent manner. In addition, YH effectively regulated the gene expression of insulin-like peptides related to carbohydrate metabolism as well as genes related to lipogenesis. The TG content was significantly reduced at a YH concentration of 0.5%, confirming that the active compound in YH effectively suppresses fat accumulation. These findings support that YH is a potential anti-obesity food material via regulating carbohydrate metabolism in Drosophila. Full article
(This article belongs to the Special Issue Adipokines as Peripheral Signals for the Integration of Energy Balance and Reproduction)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop