Special Issue "The Function and Regulation Mechanism of ncRNAs in Adipogenesis"
Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 3310
Interests: adipogenesis; transcriptional regulation; epigenetics; functional genomics
Adipogenesis is a very complicated process, which can be divided into two main phases: commitment (from MSCs to preadipocytes) and terminal differentiation (from preadipocytes to adipocytes). It has been reported that many transcriptional factors, such as PPARγ, C/EBPα, ZFP423, etc., are involved in the regulation of adipogenesis.
Non-coding RNAs (ncRNAs) constitute the majority of mammalian transcriptomes. ncRNAs could be divided into classical ncRNA (tRNA and rRNA), microRNA (miRNAs), lncRNA, circRNA, etc. Previously, ncRNAs were considered “junk”. Recently, more and more studies have shown that ncRNAs play an important role in adipogenesis. In particular, lncRNA and circRNA play roles as RNA decoys, microRNA sponges, and RNP components, as well as in the recruitment of chromatin modifiers, translation inhibition, splicing modulation, degradation, etc.
We welcome contributions from authors who focus on ncRNA in adipogenesis. We believe these findings will be helpful in treating obesity and type 2 diabetes, and improving meat quality. Some of the highlighted topics are as follows:
- Identification of new ncRNAs in adipogenesis;
- Exploration of the role of ncRNAs in adipogenesis;
- Interaction mechanism of ncRNAs with other regulators in adipogenesis.
Dr. Anning Li
Dr. Bo Wang
Manuscript Submission Information
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