Special Issue "Amino Acid Metabolism and Disease 2.0"
Deadline for manuscript submissions: 20 October 2023 | Viewed by 4694
Interests: amino acid metabolism; one-carbon metabolism; sulfur amino acids and liver disease; homocysteine and hearing loss; structure/function relationships; redox stress; cysteine modifications
Special Issues, Collections and Topics in MDPI journals
The current Special Issue is the continuation of our 2021 Special Issue “Amino Acid Metabolism and Disease”.
Amino acids are better known as the building blocks of proteins, but their role extends to the synthesis of other key compounds for the function of any organism and even the post-translational modification of proteins. Among these additional roles, a special place is reserved for the synthesis of S-adenosylmethionine, which seems to be involved in as many reactions as ATP, but also for the synthesis of neurotransmitters, glutathione, and nucleotides. Pathways of amino acid metabolism are interconnected to recycle essential amino acids, thus guaranteeing their supply during unfavorable conditions, but also with energy metabolism. Vitamins and cations are important for enzymes in these routes, further linking amino acid metabolism to nutrition, an aspect to be considered in pathological states where patients tend to change their habits or decrease their daily food ingestion. Moreover, human mutations in genes involved in amino acid metabolism are constantly being discovered, studied, and linked to a variety of outcomes, including major and rare diseases. This Special Issue focuses on these additional roles of amino acids, how pathological impairments of their metabolism impact cell function, and whether they can be prevented or ameliorated by drugs and/or nutritional interventions.
Dr. Maria A. Pajares
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- amino acid transport
- essential amino acids
- hearing loss
- liver disease
- neurological disorders
- oligomerization state
- post-translational modifications
- protein–protein interactions
- structure/function relationships
- sulfur amino acids