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Special Issue "Extracellular Vesicles in Cancer Prevention and Treatment"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 October 2023 | Viewed by 95

Special Issue Editors

Department of Experimental Medicine, University of Rome “Sapienza”, 00164 Rome, Italy
Interests: cancer; cancer target therapy; nutraceutics; cancer vaccines; extracellular vesicles; biomarkers; ultrastructural pathology
Special Issues, Collections and Topics in MDPI journals
Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata”, 00133 Rome, Italy
Interests: anticancer; polyphenols; cancer nutraceutical and immunotherapy; natural compounds on cancer cell growth
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cell-derived extracellular vesicles (EVs) have attracted attention in recent years. EVs are micro- or nano-sized membrane vesicles secreted from different cell types, including immune/inflammatory, mesenchymal, endothelial, and cancer cells. EVs participate in intercellular communication and contain different active cargos, including proteins, RNA, miRNAs, and DNA, that modulate cellular behavior. EVs regulate several cellular processes, modifying tissue microenvironments, and inducing angiogenesis, invasion, progression, and metastasis during cancer development. Moreover, EVs can be isolated from biological fluids, such as blood plasma, serum, saliva, and urine. Accordingly, EVs are promising biomarkers candidates for the prevention, early diagnosis, and follow-up of cancer patients. The opportunity to incorporate active biomolecules, nucleic acids, and drugs into EVs in conjunction with the capability of EVs to overcome natural barriers and with their cell-targeting properties could render the EVs effective therapeutic tools for cancer therapy.

This Special Issue will focus on the use of EVs as preventive or therapeutic tools in cancer. The authors are invited to contribute with a review or full research paper for peer review to this Special Issue.

Dr. Laura Masuelli
Prof. Dr. Roberto Bei
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • extracellular vesicles
  • biomarkers
  • cancer
  • prevention
  • therapy

Published Papers

This special issue is now open for submission.
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