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Special Issue "Transport of Nutrients and Ions Relevant to Human Pathophysiology"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 15 November 2023 | Viewed by 114

Special Issue Editors

Department DiBEST (Biologia, Ecologia, Scienze della Terra), University of Calabria, Via P. Bucci 4c, 87036 Arcavacata di Rende (CS), Italy
Interests: membrane transporters; drug transport; drug interaction; proteoliposomes; recombinant protein production and purification; carnitine; glutamine; acetylcholine
Dr. Tiziano Mazza
E-Mail Website
Guest Editor
Department DiBEST, Unit of Biochemistry & Molecular Biotechnology, University of Calabria, Arcavacata di Rende, Italy
Interests: proteoliposome; membrane proteins; protein purification,; cryo-EM

Special Issue Information

Dear Colleagues,

Membrane transporters are essential players in cell metabolism since they sustain homeostasis-mediating nutrients and cofactor intestinal absorption, renal reabsorption, and distribution to various tissues. These processes are achieved by the concerted action of transporters belonging to four protein superfamilies: the solute carrier (SLC), the ATP-binding cassette (ABC), ATPases, and channels. SLCs make up the largest group of membrane transporters, which includes transporters for nutrients, cofactors (such as ions), and cofactor precursors (such as vitamins). The crucial role of transporters is definitively revealed by human diseases caused by various defects. Moreover, the altered expression of several transporters is a hallmark of cancer. Therefore, understanding the function and the regulation of nutrient transporters is mandatory for the knowledge and treatment of many diseases. Identification, functional, and structure–function relationship studies have been performed using different and complementary experimental tools from ex vivo and in vitro systems, as well as in silico methodologies. This Special Issue aims to cover recent, novel, and promising research achievements in the field of these transporters, stimulating future research on these important proteins. Original manuscripts and reviews dealing with specific and/or systematic aspects of nutrient and ion transportation, metabolism, and pathophysiology from outstanding experts on the topic are most welcome.

Prof. Dr. Lorena Pochini
Dr. Tiziano Mazza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • membrane transporters
  • SLC
  • transport system
  • nutrient transport
  • ion transport
  • metabolism
  • human pathophysiology

Published Papers

This special issue is now open for submission.
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