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Two- and Three-Dimensional Nanostructured Materials for Biosensing Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 30 July 2024 | Viewed by 478

Special Issue Editor

Special Issue Information

Dear Colleagues,

Two- and three-dimensional nanostructured materials are systems with one or more dimensions or features reduced to the nanoscale, thus presenting some unique and sometimes unprecedented physicochemical properties. The possibility of manipulating and regulating these properties makes them suitable for a variety of biosensing applications. A biosensor is identified based on its biomimetic receptor unit with exceptional specificities toward corresponding analytes. These analytes often stem from biological-origin macromolecules like DNAs of bacteria or viruses, as well as proteins generated from the immune systems of infected organisms. Moreover, in many cases, analytes may be endogenous small molecule metabolites, making them attractive biomarkers for the clinical diagnosis or prognosis. Furthermore, in many cases, analytes may be endogenous small-molecule metabolites, which are attractive biomarkers for clinical diagnosis or prognosis.

The aim of this Special Issue is to bring together original and high-quality research papers covering the most recent advances, as well as comprehensive reviews addressing state-of-the-art topics in the field of the nanostructured materials for biosensing applications.

In advance, I would like to acknowledge the authors and reviewers who participate in the elaboration of this Special Issue and contribute to the development of research into nanostructured materials for biosensing applications.

Dr. Ádám Juhász
Guest Editor

Manuscript Submission Information

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Keywords

  • biosensors
  • biomimetics
  • nanoparticles
  • nanoclusters
  • quantum dots
  • nanostructured carbon
  • self-assembled structures

Published Papers (1 paper)

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Research

18 pages, 7898 KiB  
Article
Chemiresistors Based on Hybrid Nanostructures Obtained from Graphene and Conducting Polymers with Potential Use in Breath Methane Detection Associated with Irritable Bowel Syndrome
by Alexandru F. Trandabat, Romeo C. Ciobanu, Oliver Daniel Schreiner, Thomas Gabriel Schreiner and Sebastian Aradoaei
Int. J. Mol. Sci. 2024, 25(10), 5552; https://doi.org/10.3390/ijms25105552 - 20 May 2024
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Abstract
This paper describes the process of producing chemiresistors based on hybrid nanostructures obtained from graphene and conducting polymers. The technology of graphene presumed the following: dispersion and support stabilization based on the chemical vapor deposition technique; transfer of the graphene to the substrate [...] Read more.
This paper describes the process of producing chemiresistors based on hybrid nanostructures obtained from graphene and conducting polymers. The technology of graphene presumed the following: dispersion and support stabilization based on the chemical vapor deposition technique; transfer of the graphene to the substrate by spin-coating of polymethyl methacrylate; and thermal treatment and electrochemical delamination. For the process at T = 950 °C, a better settlement of the grains was noticed, with the formation of layers predominantly characterized by peaks and not by depressions. The technology for obtaining hybrid nanostructures from graphene and conducting polymers was drop-casting, with solutions of Poly(3-hexylthiophene (P3HT) and Poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-bithiophene] (F8T2). In the case of F8T2, compared to P3HT, a 10 times larger dimension of grain size and about 7 times larger distances between the peak clusters were noticed. To generate chemiresistors from graphene–polymer structures, an ink-jet printer was used, and the metallization was made with commercial copper ink for printed electronics, leading to a structure of a resistor with an active surface of about 1 cm2. Experimental calibration curves were plotted for both sensing structures, for a domain of CH4 of up to 1000 ppm concentration in air. A linearity of the curve for the low concentration of CH4 was noticed for the graphene structure with F8T2, presenting a sensitivity of about 6 times higher compared with the graphene structure with P3HT, which makes the sensing structure of graphene with F8T2 more feasible and reliable for the medical application of irritable bowel syndrome evaluation. Full article
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