Plant Genome Editing
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 4210
Special Issue Editor
Special Issue Information
Dear Colleagues,
Genome-editing technology enables breeders to precisely adjust traits of interest with unprecedented control and efficiency for the first time. The emergence of genome editing has aroused people's enthusiasm, but also triggered controversy, bringing challenges to global regulation and governance. Plant genome editing plays a key role in gene function research, crop genetic improvement, yield improvement, disease and pest control, molecular precision breeding, etc. It will make a significant contribution to achieving a variety of sustainable development goals. With the rapid progress of science, policy and management methods have become increasingly important. At present, some countries have made legislative adjustments to these technologies or issued guidelines to support the use of genome editing. Other countries have also discussed the future path of this, but the legal classification is not clear or the consensus is hindered due to the debate on transgenic plants.
This research topic aims to collect articles on the latest progress and future goals of genome editing, as well as contributions to regulatory, social and socio-economic aspects, ethics, risk assessment, management and biosafety research. We will focus on how to define the legal status of genome-editing products and how to carry out international policy coordination. Authors are particularly invited to discuss one or more of the following aspects:
1) Background—Plant genome editing:
- Existing technologies and applications;
- Future expectation of genome editing;
- How to address global challenges.
2) Supervision, assessment, safety:
- Summary of current biosafety regulations;
- How to detect/execute;
- Alternative regulatory approaches;
- Does the established risk assessment strategy fit the purpose?
- Methods for assessing non-targeted changes in the genome;
- Triggers to guide appropriate and proportionate risk assessments.
3) Social, economic, morality and ethics:
- How to responsibly develop and use genome editing: concepts, challenges and examples;
- Cognition, such as similarities and differences between GM foods and genome-editing foods;
- Possible social and socio-economic impacts of different regulatory scenarios;
- Genome editing as a turning point in the ethical debate on plant genetic modification;
- Ethical reasonableness of the precautionary principle on genome-editing risk issues.
Dr. Lei Gao
Guest Editor
Manuscript Submission Information
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Keywords
- plant genome editing
- Cas9/Cas12a
- CRISPR/CRISPRa/CRISPRi
- anti-CRISPR
- gene editing
- off target impact
- prime editing
- bioinformatics/database
