ijms-logo

Journal Browser

Journal Browser

Special Issue "Molecular Metabolisms and Regulations of Algae"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: 15 February 2024 | Viewed by 723

Special Issue Editor

Biological Faculty, Saint-Petersburg State University, Saint-Petersburg 199034, Russia
Interests: green and red algae; nitrogen metabolism; nitric oxide; S-nitrosation; PII proteins; stress responses

Special Issue Information

Dear Colleagues,

Eukaryotic algae are remarkably diverse in terms of habitat, morphology, physiology, and biochemistry, and they play a critical role in global ecology. Algae are useful models for studying metabolic processes in photosynthetic organisms and potential renewable platforms for the production of beneficial chemicals. Algae adapt to various environmental conditions by changing many aspects, from gene expression to cell physiology and morphology, through the regulation of primary and secondary metabolism. Characterizing algal metabolism and its regulation is the key to understanding their role in the environment and unlocking their potential for biotechnology applications.

This Special Issue provides an open platform for the discussion of recent developments in this field, focusing on novel aspects of molecular metabolism in algae, from genes regulation and signal pathways to protein modification and enzyme activity control.

Original papers, review articles, and perspectives from experts in the field are welcome.

Prof. Dr. Elena Ermilova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • algal enzymes
  • metabolic pathways
  • information-processing proteins
  • signal molecules and transducers
  • central metabolism
  • secondary metabolism
  • anaerobic metabolism
  • fermentation
  • omics technologies
  • biofuel production
  • protein post-translational modifications

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Article
N-Acetyl-L-glutamate Kinase of Chlamydomonas reinhardtii: In Vivo Regulation by PII Protein and Beyond
Int. J. Mol. Sci. 2023, 24(16), 12873; https://doi.org/10.3390/ijms241612873 - 17 Aug 2023
Viewed by 354
Abstract
N-Acetyl-L-glutamate kinase (NAGK) catalyzes the rate-limiting step in the ornithine/arginine biosynthesis pathway in eukaryotic and bacterial oxygenic phototrophs. NAGK is the most highly conserved target of the PII signal transduction protein in Cyanobacteria and Archaeplastida (red algae and Chlorophyta). However, there is still [...] Read more.
N-Acetyl-L-glutamate kinase (NAGK) catalyzes the rate-limiting step in the ornithine/arginine biosynthesis pathway in eukaryotic and bacterial oxygenic phototrophs. NAGK is the most highly conserved target of the PII signal transduction protein in Cyanobacteria and Archaeplastida (red algae and Chlorophyta). However, there is still much to be learned about how NAGK is regulated in vivo. The use of unicellular green alga Chlamydomonas reinhardtii as a model system has already been instrumental in identifying several key regulation mechanisms that control nitrogen (N) metabolism. With a combination of molecular-genetic and biochemical approaches, we show the existence of the complex CrNAGK control at the transcriptional level, which is dependent on N source and N availability. In growing cells, CrNAGK requires CrPII to properly sense the feedback inhibitor arginine. Moreover, we provide primary evidence that CrPII is only partly responsible for regulating CrNAGK activity to adapt to changing nutritional conditions. Collectively, our results suggest that in vivo CrNAGK is tuned at the transcriptional and post-translational levels, and CrPII and additional as yet unknown factor(s) are integral parts of this regulation. Full article
(This article belongs to the Special Issue Molecular Metabolisms and Regulations of Algae)
Show Figures

Figure 1

Back to TopTop