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Molecular Metabolisms in Cartilage Health and Diseases 3.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 177

Special Issue Editor

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Guest Editor
Advanced Research Center for Oral and Craniofacial Sciences, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan
Interests: cartilage; chondrocytes; CCN proteins; bone; osteoblasts
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Special Issue Information

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue “Molecular Metabolisms in Cartilage Health and Diseases 2.0”.

Cartilage is a unique tissue as it is avascular and composed of only chondrocytes. Vascular invasion into the cartilage is a key step towards endochondral bone formation, as well as being involved in the pathogenesis of osteoarthritis. Because of the lack of blood flow, the regeneration or repair of damaged cartilage, such as those in osteoarthritis, is difficult to be achieved. The old and new problems in cartilage medicine are how to maintain cartilage homeostasis and how to regenerate or repair damaged cartilage. Many factors, such as growth factors, transcription factors, nutrition and its metabolites, extracellular matrix, and physical forces, are involved in cartilage growth, homeostasis, and regeneration. This Special Issue titled “Molecular Metabolisms in Cartilage Health and Diseases 3.0” focuses on the recent progress in the molecular aspects of cartilage metabolism and its regulation in normal and diseased cartilage.

Dr. Masaharu Takigawa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cartilage
  • chondrocytes
  • growth
  • regeneration
  • endochondral ossification
  • arthritis
  • joint
  • growth factors
  • mechanical stress
  • nutrition

Published Papers

This special issue is now open for submission.
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