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Special Issue "Chemotherapeutics Based on Metals: Bioactivity and Mechanisms of Action"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 20 December 2023 | Viewed by 241

Special Issue Editors

Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Interests: medicinal chemistry; metal-based drugs; anticancer drugs; oxidative stress; organometallics
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Interests: bioinorganic chemistry; organic chemistry; medicinal chemistry; development of anticancer compounds; phosphorus ligands

Special Issue Information

Dear Colleagues,

The severe side effects observed by patients undergoing chemotherapy with platinum drugs (cisplatin, carboplatin, oxaliplatin) are the main disadvantages in treatment of tumor diseases. Moreover, the onset of cancer chemoresistance to platinum-based chemotherapy represents an additional major limitation to its clinical practice. Therefore, approaches to overcome the toxicity and/or tumor resistance to platinum-containing chemotherapies dominate the field of non-platinum drugs. On the other hand, application of metals beyond platinum may open the possibility to discover novel biological targets and therefore novel modes of action.

In this Special Issue, we will focus on novel approaches to develop metal-containing drug candidates.

Prof. Dr. Elena R. Milaeva
Dr. Alexey Nazarov
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cancer

  • chemotherapy
  • non-platinum metal-containing drugs
  • biological targets
  • biomolecular mode of action

Published Papers

This special issue is now open for submission.
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