Fungal Molecular Mechanisms, Fungal Infections and Antifungal Drugs
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (15 December 2023) | Viewed by 2875
Special Issue Editor
Interests: phytochemistry; QSAR; molecular docking; data analysis; pharmaceutical law and ethics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Fungi are eukaryotic organisms which belong to a distinct kingdom of their own—not plants or animals—this kingdom includes diverse microscopic (e.g., yeasts and molds) or macroscopic (e.g., edible mushrooms) species.
Whereas most fungal species are harmless to humans, a minority can cause cause serious ailments in humans, particularly in patients with compromised immune systems. Such fungal diseases include aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis, mycetomas, paracoccidioidomycosis, and pneumocystis pneumonia. A set of fungal organisms (dermatophytic and keratinophilic species) have a tropism for human skin, as well as eyes, nails, and hair, being associated with localized infections (e.g., dermatophytosis and tinea pedis). Fungal spores, which are microscopic particles that have key roles in non-sexual fungal reproductions, can be responsible for a number of allergies, most often from the middle of summer to early autumn. Medicinal products that can be used to prevent and conquer fungal infections are urgently needed in modern medicine.
This Special Issue aims to provide a platform to make the results of research regarding molecular mechanistic aspects of fungi available, with a particular focus on research regarding potential treatments and novel signaling pathways relevant to overcoming fungal infections. Papers exploring antifungal development (from both synthetic and natural product starting points), particularly antifungal screening, antifungal biological target identification and validation, repurposing authorized molecules for antifungal purposes, molecular mechanisms involved in efficacy or safety aspects as well as in resistance to current treatments, the physicochemical properties of antifungal compounds, -omics approaches in understanding fungal infection and reproduction, as well as structure–activity relationships, will be considered for publication in this Special Issue.
We warmly welcome submissions of original papers and reviews based on results from molecular viewpoints.
Prof. Dr. Robert Ancuceanu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- fungal
- fungal infections
- antifungal drugs
- antifungal compounds
- antifungal molecular targets
- chemical synthesis
- natural compounds
- structure-activity relationship
