Polyphenols Hazard and Safety Assessment in Human Health and Food Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 2190
Special Issue Editors
Interests: nanomaterials; nanotechnology; carbon-based materials preparation and characterization; graphene; green chemistry; electrochemistry; detection protocols; sensors; graphene-based modified electrodes; electrochemical mechanisms; portable sensing solutions; food science; polyphenols; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Interests: food and beverages authentication; traceability; metabolomics; chemometrics; artificial intelligence
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Throughout the last few decades, polyphenols—plant-derived functional ingredients with different molecular structures—have become an emerging field of interest as a direct result of growing evidence suggesting their positive involvement in various health-related biological activities, through the regulation of metabolism and cell proliferation, including antioxidant, anti-inflammatory, and anticancer behavior. Besides their therapeutic effects, polyphenols’ qualities have been exploited in the food industry to boost product stability and prevent other molecules’ oxidation. This has resulted in an overestimation of the present understanding of their effects, while disregarding the fact that some polyphenol-rich foods were formerly thought to be inedible and antioxidant supplementation treatments have been linked to negative outcomes such as increased mortality or stroke. The dangers of polyphenol consumption are difficult to estimate because the bulk of risk studies have been conducted in vitro. Furthermore, the absence of established methodologies, the analysis expenses, shelf instability, and a lack of intake benchmarks make it difficult to add label content information. As a result, there is an increasing demand for trustworthy procedures that can provide a rapid and accurate response concerning polyphenol detection and quantification in food and pharmaceutical sectors, and further research is necessary to obtain full insight regarding their molecular mechanism, characterizing the short- and long-term health effects. Therefore, the intent of this Special Issue is to summarize and broaden the knowledge on polyphenol action mechanisms and development of economic and sensitive materials and analytical tools capable of supporting the control of polyphenol content and to explain their potential protective/toxic effects on the human body. We invite authors to submit both original research and review articles based on classic procedures recognized as safety control techniques, as well as the development and validation of new protocols and alternative methods that consist in the involvement of either innovative experimental setups or advanced data processing tools, such as supervised statistical methods or artificial intelligence (AI).
Dr. Lidia Magerusan
Dr. Dana Alina Magdas
Guest Editors
Manuscript Submission Information
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Keywords
- polyphenols
- food safety
- health risk evaluation
- graphenes-based sensors
- electrochemical detection
- chemometrics
- artificial intelligence
- metabolomics
