Special Issue "Discovering Novel Bioactive Small Molecules against Drug-Resistant and Multidrug-Resistant Cancers"
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 1256
Interests: multidrug resistance mechanisms; ATP-binding cassette proteins; protein kinase inhibitors; medicinal chemistry; natural products chemistry
Special Issues, Collections and Topics in MDPI journals
A major obstacle to clinical cancer chemotherapy is the development of acquired drug-resistant or multidrug-resistance (MDR) phenotype in cancer cells. Multiple molecular mechanisms such as increased drug efflux, reduced drug uptake, enhanced cellular repair mechanisms, and alterations of drug metabolism or drug targets are known to contribute to the reduced sensitivity of cancer cells to anticancer drugs. In the past decade, many synthetic compounds have been developed; natural bioactive compounds have been discovered, and numerous therapeutic agents have been repurposed to improve the efficacy of anticancer drugs in these drug-resistant cancer cells. This Special Issue on “Discovering novel bioactive small molecules against drug-resistant and multidrug-resistant cancers” warmly invites researchers to contribute original research articles, review articles, and short communications related to all aspects of drug development and therapeutic approaches against drug-resistant and multidrug-resistant cancers.
Prof. Dr. Chung-Pu Wu
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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