Oxidative Stress and Damage Precipitated by Space-Like Conditions That Mimic Ageing: Physiological and Molecular Ground and Flight Parallels 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 224
Special Issue Editor
2. The National Aeronautics and Space Administration (NASA Retired) Johnson Space Center, Houston, TX 77058, USA
Interests: ageing; oxidative stress and damage; antioxidants; radiation toxicity; inflammation; genomics; proteomics; metabolomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Technological advances now allow the planning of deep space exploration missions with the aim to discover new habitats for humankind. The National Aeronautics and Space Administration (NASA) has spearheaded this effort and the research into the identification of risks to crew members associated with such lengthy missions. Exciting work from a multitude of investigators across the US, Canada, Europe, and Japan has identified oxidative damage as a key risk factor to major organs and systems physiologies that could pose a threat to the health of astronauts and the success of the mission. Through “omics technologies” and other advanced analyses, we now have defined methods to begin a comparison of human physiological responses in space flight to ground-based One Earth Normal (OEN) physiologies. This Special Issue of IJMS is dedicated to providing a comprehensive overview of the identified risks in space flight and habitation and will focus on ground-based vs. flight comparisons of how oxidative stress, when exposed to space-relevant conditions such as cosmic/galactic radiation, solar particle events, hypogravity (G-variations and partial gravity), and hypoxia/hyperoxia, or any aggregate combination of stressors, affects human physiology. Much can be learned from the examination and analysis of the parallel human physiology response and how it adapts to the hostile environment of space.
Dr. Thomas J. Goodwin
Guest Editor
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Keywords
- hypoxia/hyperoxia
- omics analyses
- cosmic/galactic radiation
- solar particles
- space travel
- Mars habitation
- environmental stressors
- hypogravity/gravity variations
- oxidative stress
