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The Chitosan Biomaterials: Advances and Challenges—2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 2481

Special Issue Editors


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Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: quality by design (QbD); analytical quality by design (AQbD); drug systems formulation (chitosan); surfaces’ characteristics (wettability/hidrophilicity/hidrophobicity—pharmaceutical powders)
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: biomaterials (collagen drug delivery systems); rheology; cosmeceuticals; drug systems formulation and technological processes optimization; response surface methodology; Taguchi design
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: targeted drug delivery; nanoparticulate systems; solubility enhancement techniques; biotechnology; topical/transdermal drug delivery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chitosan is a versatile biopolymer, with applications in drug delivery systems, vaccine formulations, wound healing, tissue regeneration, cosmetics, dentistry, food packing, agriculture, among others. The basic properties of chitosan, which make it an optimal material for use, are as follows: biocompatibility, biodegradability, mucoadhesion, and enhancement of permeability. It also has its own actions, such as antibacterial, antifungal, hemostatic, and antioxidant, which provide it with an advantage for use in various fields. Recent research has shown that chitosan also has immunostimulatory, anti-tumor, and anti-inflammatory actions.

Aside from its numerous actions and effects, chitosan has amino and hydroxyl functional groups in its structure, which lead to chitosan derivatives with improved physico-chemical properties and effects being obtained, and to the establishment of interactions with a variety of molecules used to develop biomaterials.

Through the Special Issue “The Chitosan Biomaterials: Advances and Challenges—2nd Edition”, we aim to gather original research and review articles that include the development, preparation, actions and evaluation of various biomaterials based on chitosan and its derivatives, as well as their applications.

Prof. Dr. Lacramioara Popa
Prof. Dr. Mihaela Violeta Ghica
Prof. Dr. Cristina Elena Dinu-Pirvu
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chitosan
  • chitosan biomaterials
  • chitosan derivatives
  • drug delivery
  • wound healing
  • tissue regeneration
  • dentistry
  • smart biomaterials

Published Papers (2 papers)

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Research

16 pages, 15654 KiB  
Article
Chitosan-Based Beads Incorporating Inorganic–Organic Composites for Copper Ion Retention in Aqueous Solutions
by Andreea Miron, Tanta-Verona Iordache, Artur J. M. Valente, Luisa Maria Rocha Durães, Andrei Sarbu, Georgeta Ramona Ivan, Anamaria Zaharia, Teodor Sandu, Horia Iovu and Anita-Laura Chiriac
Int. J. Mol. Sci. 2024, 25(4), 2411; https://doi.org/10.3390/ijms25042411 - 18 Feb 2024
Viewed by 985
Abstract
In recent years, there has been a challenging interest in developing low-cost biopolymeric materials for wastewater treatment. In the present work, new adsorbents, based on different types of chitosan (commercial, commercial chitin-derived chitosan and chitosan synthesized from shrimp shell waste) and inorganic–organic composites [...] Read more.
In recent years, there has been a challenging interest in developing low-cost biopolymeric materials for wastewater treatment. In the present work, new adsorbents, based on different types of chitosan (commercial, commercial chitin-derived chitosan and chitosan synthesized from shrimp shell waste) and inorganic–organic composites have been evaluated for copper ions removal. The efficacy of the synthesis of chitosan-based composite beads has been determined by studying various characteristics using several techniques, including FTIR spectroscopy, X-ray diffraction, porosimetry (N2 adsorption), and scanning electron microscopy (SEM). Adsorption kinetics was performed using different adsorption models to determine the adsorption behavior of the materials in the aqueous media. For all composite beads, regardless of the type of chitosan used, good capacity to remove copper ions from simulated waters was observed (up to 17 mg/g), which proves that the new materials hold potential for heavy metal retention. However, the adsorption efficiency was influenced by the type of chitosan used. Thus, for the series where commercial chitosan (CC) was used, the removal efficiency was approximately 29%; for the series with chitosan obtained from commercial chitin (SC), the removal efficiency was approximately 34%; for the series with chitosan enriched with CaCO3 (SH), the removal efficiency was approximately 52%. Full article
(This article belongs to the Special Issue The Chitosan Biomaterials: Advances and Challenges—2nd Edition)
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16 pages, 1864 KiB  
Article
High-Density Chitosan Induces a Biochemical and Molecular Response in Coffea arabica during Infection with Hemileia vastatrix
by Julio César López-Velázquez, Soledad García-Morales, Gloria Paola López-Sánchez, Mayra Itzcalotzin Montero-Cortés, Alberto Uc-Várguez and Joaquín Alejandro Qui-Zapata
Int. J. Mol. Sci. 2023, 24(22), 16165; https://doi.org/10.3390/ijms242216165 - 10 Nov 2023
Cited by 1 | Viewed by 892
Abstract
The coffee industry faces coffee leaf rust caused by Hemileia vastratix, which is considered the most devastating disease of the crop, as it reduces the photosynthetic rate and limits productivity. The use of plant resistance inducers, such as chitosan, is an alternative [...] Read more.
The coffee industry faces coffee leaf rust caused by Hemileia vastratix, which is considered the most devastating disease of the crop, as it reduces the photosynthetic rate and limits productivity. The use of plant resistance inducers, such as chitosan, is an alternative for the control of the disease by inducing the synthesis of phytoalexins, as well as the activation of resistance genes. Previously, the effect of chitosan from different sources and physicochemical properties was studied; however, its mechanisms of action have not been fully elucidated. In this work, the ability of food-grade high-density chitosan (0.01% and 0.05%) to control the infection caused by the pathogen was evaluated. Subsequently, the effect of high-density chitosan (0.05%) on the induction of pathogenesis-related gene expression (GLUC, POX, PAL, NPR1, and CAT), the enzymatic activity of pathogenesis-related proteins (GLUC, POX, SOD, PPO, and APX), and phytoalexin production were evaluated. The results showed that 0.05% chitosan increased the activity and gene expression of ß-1,3 glucanases and induced a differentiated response in enzymes related to the antioxidant system of plants. In addition, a correlation was observed between the activities of polyphenol oxidase and the production of phytoalexin, which allowed an effective defense response in coffee plants. Full article
(This article belongs to the Special Issue The Chitosan Biomaterials: Advances and Challenges—2nd Edition)
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