Special Issue "Diagnosis, Therapeutic Approaches and Future Perspectives in the Treatment of Rhinitis"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: 30 November 2023 | Viewed by 5739
Interests: rhinology; OSA; otology; laryngology; machine learning
Interests: CRS; allergy; rhinitis; biologics; nasal polyps; quality of life; sinusitis
Sinonasal disorders possess an extremely wide prevalence in the population and considerably affect the patient's quality of life. The diagnosis and treatment of nasal pathologies benefits from ever more current technological innovations, both in the medical and surgical fields. Surgical approaches could employ technologies such as cryosurgery, laser, electrocautery, molecular quantum resonance, and the recently introduced Kinetic oscillation stimulation at the expense of more aggressive traditional methods. The primary objective remains the preservation of the mucosa and the restoration of a physiological mucociliary clearance. On the other hand, the complete understanding of the pathophysiological mechanisms underlying dysventilation and chronic nasal inflammation permitted the introduction of molecular target therapies such as the recently approved monoclonal drugs.
Another relevant aspect in chronic inflammatory pathology of the nasal sinus is multifactoriality, which involves multiple environmental, immunological, and genetic factors. Although several potential etiological agents have been recognized as allergic comorbidities, specific microbes, mucociliary disorders, and altered epithelial barriers, the etiology remains unclear. Recent advances in culture-independent molecular techniques have improved understanding of the interactions between upper airway microbiota and chronic inflammation states and the usefulness of genetic screening as a useful predictor of relapse and treatment response.
The current monoclonal biological therapy, exploiting these pathways, has shown promising results on tissue remodeling, the control of the inflammatory immune response, the metabolism of arachidonic acid up to the recovery of mucociliary clearance, and the sense of smell of patients with chronic rhinosinusitis.
Our Special Issue aims to show the different facets of the most current therapies in the rhinology field, enhancing the increasingly less invasive approaches aimed at restoring the nasal sinus function and understanding through the most recent diagnostics available, such as may be the most promising treatment targets.
We are prioritizing high-quality original studies, but also welcome well-designed meta-analyses and reviews. We look forward to your contribution.
Dr. Antonino Maniaci
Prof. Dr. Salvatore Cocuzza
Prof. Dr. Ignazio La Mantia
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- minimally invasive surgical treatment
- turbinate surgery, smell and nasal mucociliary clearance
- CRS, allergy, rhinitis
- Th2 inflammation
- nasal polyps
- quality of life
- nasal microbiome
- nasal polymorphisms
- nasal genetics