Special Issue "Sleep and Chronic Diseases"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: 31 January 2024 | Viewed by 9033
Interests: sleep; physical activity; nutrition; lifestyle; chronic disease
Special Issues, Collections and Topics in MDPI journals
Insufficient sleep may be low in quality, short in duration, or both. It increases sympathetic activity and pro-inflammatory cytokines, both of which increase insulin resistance. Advanced glycation end products are significantly increased in chronic sleep insufficiency, which could increase insulin resistance. Stage 3 in sleep is the most crucial sleep stage because of releasing growth hormone (GH) and GH releasing hormone (GHRH). They induce fat burning, bone building, and general repair and regeneration. The longest-duration stage 3 takes place before midnight. Delayed sleep onset suppresses the largest GH pulse, increases ghrelin and decreases leptin. Ghrelin stimulates appetite, whereas leptin does the reverse. All these changes lead to weight gain, less repair and more inflammation, predisposing the body to chronic disorders.
Astrocytes are special giant cells in brain interstitial fluids that play a major role in β amyloid and tau cleanup. Their activity is increased by GHRH. Slow-wave sleep insufficiency prohibits optimum GHRH needs, leading to impaired peripheral clearance of extracellular β amyloid and intracellular tau neurofibrillary tangles. Accumulations of these neurotoxins start immediately after one night of sleep insufficiency and they potentiate each other’s destructive effects on the structures and functions of neurons, causing neuronal death. The results are interference with decision making and increased consumption of unhealthy snacks in late sleepers. High levels of β amyloid may lead to sleep fragmentation, worsening of sleep quality and daytime somnolence. Concentration will be more difficult, and performance will be reduced. Cognition will be deteriorated in the long term.
This Special Issue plans to focus on the most recent findings in the relationship between sleep insufficiency and chronic diseases.
Potential topics include, but are not limited to:
- Comparing sleep and other lifestyle factors such as physical activity and nutrition in triggering, continuing or exacerbating chronic diseases;
- Interaction of sleep and other lifestyle factors such as physical activity and nutrition in restoring and maintaining health;
- Strength of associations between sleep and different chronic diseases;
- Mechanisms of associations between sleep and various chronic diseases.
Dr. Abbas Smiley
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- physical activity
- chronic disease