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Special Issue "The Epidemiology of Sleep-Disordered Breathing and Its Implications in Adults and Children"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 944

Special Issue Editor

Sleep Medicine Center, Department of Otolaryngology, University Medical Center of Johannes Gutenberg University Mainz, 55131 Mainz, Germany
Interests: sleep medicine; obstructive sleep apnea; respiratory arousal; OSA comorbidities; OSA surgery; hypoglossal nerve stimulation; insomnia

Special Issue Information

Dear Colleagues,

Obstructive sleep apnea is a widespread disease affecting a large proportion of the adult population in industrialized countries. But children also struggle with sleep apnea for various reasons. Most importantly, the increased prevalence of obesity has contributed to the rise in OSA prevalence. The impact of sleep apnea on each individual patient, in the form of comorbidities such as cardiovascular events, psychological stress and also accidents attributable to daytime sleepiness, is immense. The many effects on various systems of an individual are probably not yet recognized or sufficiently studied. A portion of the population also suffers from sleep apnea due to sickness-related absences from work and losses in performance due to daytime sleepiness. Because of this, current research is heavily focused on both methods of rapid and cost-effective diagnosis and treatment of obstructive sleep apnea. In this Special Issue, we would like to take a closer look at the impact of OSA on the health of the individual and on society. In addition, we would like to explore methods that can simplify the diagnosis, make it more cost effective or that can simply extend the diagnostics and therapy of sleep apnea.

Dr. Katharina Bahr
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obstructive sleep apnea
  • burden of disease
  • polysomnography
  • sleep study
  • respiratory distress
  • hypopnea
  • arousal
  • OSA-therapy
  • positive airway pressure

Published Papers (1 paper)

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Research

Article
Anatomic Features of the Nasal and Pharyngeal Region Do Not Influence PAP Therapy Response
Int. J. Environ. Res. Public Health 2023, 20(16), 6580; https://doi.org/10.3390/ijerph20166580 - 15 Aug 2023
Viewed by 721
Abstract
The objective of this study was to investigate to which extent anatomic features of the nasal and pharyngeal region contribute to the severity of obstructive sleep apnea (OSA) and positive airway pressure (PAP) therapy response. Therefore, 93 patients (mean age 57.5 ± 13.0 [...] Read more.
The objective of this study was to investigate to which extent anatomic features of the nasal and pharyngeal region contribute to the severity of obstructive sleep apnea (OSA) and positive airway pressure (PAP) therapy response. Therefore, 93 patients (mean age 57.5 ± 13.0 years, mean body mass index 32.2 ± 5.80 kg/m2, 75 males, 18 females) diagnosed with OSA who subsequently started PAP therapy were randomly selected from the databank of a sleep laboratory of a tertiary university medical center. Patients were subdivided based on nasal anatomy (septal deviation, turbinate hyperplasia, their combination, or none of the above), pharyngeal anatomy (webbing, tonsillar hyperplasia, their combination, or none of the above), and (as a separate group) tongue base anatomy (no tongue base hyperplasia or tongue base hyperplasia). Then, polysomnographic data (e.g., arousal index, ARI; respiratory disturbance index, RDI; apnea index, AI; hypopnea index, HI; and oxygen desaturation index, ODI) of diagnostic polysomnography (PSG) and PAP therapy control PSG were collected, grouped, and evaluated. Septal deviation, turbinate hyperplasia, or their combination did not significantly affect the assessed PSG parameters or the response to PAP therapy compared with patients without nasal obstruction (p > 0.05 for all parameters). Accordingly, most PSG parameters and the response to PAP therapy were not significantly affected by webbing, tonsil hyperplasia, or their combination compared with patients without pharyngeal obstruction (p > 0.05 for RDI, AI, HI, and ODI, respectively). However, in the pharyngeal anatomy group, ARI was significantly higher in patients with tonsil hyperplasia (p = 0.018). Further, patients with tongue base hyperplasia showed a significantly higher HI in the diagnostic PSG (p = 0.025) compared with patients with normal tongue base anatomy, but tongue base anatomy did not significantly affect the response to PAP therapy (p > 0.05 for all parameters). The influence of anatomic features of the nasal and pharyngeal region on PAP therapy response appears to be small, and generalizability of these results requires further studies. Full article
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