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Special Issue "The Pathophysiology and Treatment of Glaucoma"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (8 July 2023) | Viewed by 1089

Special Issue Editor

Department of Ophthalmology, Medical University of Graz, A-8036 Graz, Austria
Interests: glaucoma; prion

Special Issue Information

Dear Colleagues,

Glaucoma is the second most common cause of blindness worldwide, and the number of patients with glaucoma is expected to rise to 100 million by 2030 (Tham et al. 2014). Glaucoma has a huge impact on the quality of life of the affected individuals. The disease is characterized by visual field defects, which at first are not recognized but then eventually grow larger until patients lose their ability to drive and ultimately go blind. There are several risk factors for glaucoma, including genetics, corneal thickness, age and intraocular pressure. To date, lowering intraocular pressure is the only proven treatment of the disease. It can be achieved by medication, laser or surgery. We have seen a staggering number of innovations in all fields of treatment and diagnosis in the recent years, allowing us to detect glaucoma earlier and to lower intraocular pressure more efficiently. Overall, this has led to a significant reduction blindness caused by the disease. Still, about half of glaucoma patients remain undetected (Topouzis et al. 2008), and with our current diagnostic armamentarium, we can only detect glaucoma when some degree of damage has already occurred. A better understanding of the pathophysiology of the disease will certainly help to detect new markers for an earlier detection of the disease. New treatment options must be carefully evaluated by the scientific community in order to improve their usage in everyday clinical practice. Therefore, this Special Issue invites papers addressing the pathophysiology and treatment of glaucoma.

Dr. Ewald Lindner
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • glaucoma
  • filtering surgery
  • anti-glaucoma medication
  • laser ablation
  • visual fields
  • optic flow
  • optical coherence tomography
  • intraocular pressure

Published Papers (1 paper)

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Research

Article
Postoperative Pain after Different Transscleral Laser Cyclophotocoagulation Procedures
Int. J. Environ. Res. Public Health 2023, 20(3), 2666; https://doi.org/10.3390/ijerph20032666 - 02 Feb 2023
Viewed by 887
Abstract
Background: As the number of surgical options in glaucoma treatment is continuously rising, evidence regarding distinctive features of these surgeries is becoming more and more important for clinicians to choose the right surgical treatment for each individual patient. Methods: For this retrospective data [...] Read more.
Background: As the number of surgical options in glaucoma treatment is continuously rising, evidence regarding distinctive features of these surgeries is becoming more and more important for clinicians to choose the right surgical treatment for each individual patient. Methods: For this retrospective data analysis, we included glaucoma patients treated with either continuous wave (CW-TSCPC) or micropulse transscleral cyclophotocoagulation (MP-TSCPC) in an inpatient setting. Pain intensity was assessed using a numeric rating scale (NRS) ranging from 0 (no pain) to 10 (worst imaginable pain) during hospitalization. CW-TSCPC was performed using OcuLight® Six (IRIDEX Corporation, Mountain View, CA, USA) and MP-TSCPC was performed using the IRIDEX® Cyclo-G6 System (IRIDEX Corporation, Mountain View, CA, USA). Results: A total of 243 consecutive cases of TSCPC were included. Of these, 144 (59.26%) were treated with CW-TSCPC and 99 (40.74%) with MP-TSCPC. Using the univariable model, the risk for postoperative pain was observed to be lower in MP-TSCPC compared with CW-TSCPC (unadjusted: OR 0.46, 95% CI 0.24–0.84, p = 0.017), but this did not hold using the multivariable model (adjusted: OR 0.52, 95% CI 0.27–1.02, p = 0.056). Simultaneously conducted anterior retinal cryotherapy was associated with a higher risk for postoperative pain (OR 4.41, 95% CI 2.01–9.69, p < 0.001). Conclusions: We found that the occurrence of postoperative pain was not different in CW-TSCPC compared with MP-TSCPC in a multivariable model. In cases of simultaneous anterior retinal cryotherapy, the risk for postoperative pain was significantly higher. Full article
(This article belongs to the Special Issue The Pathophysiology and Treatment of Glaucoma)
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