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Food Science and Human Nutrition

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 9052

Special Issue Editors


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Guest Editor
Institute of Neurobiology, National Autonomous University of Mexico, Queretaro 76230, Mexico
Interests: nutrigenomics; in vitro gastrointestinal digestion; polyphenolic compounds; impact of food metabolites in disease models of inflammation (intestinal inflammation, colon cancer, and obesity); extraction and characterization of bioactive compounds from food matrices; food toxicology; phytochemicals

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Guest Editor
The Institute for Obesity Research, Tecnologico de Monterrey, Monterrey 64849, Mexico
Interests: obesity; inflammation; cancer; polyphenols; natural colorants; anthocyanins; peptides
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Tecnologico de Monterrey, School of Engineering and Science, Monterrey 64849, Mexico
Interests: nutrigenomics; functional foods; prebiotics; probiotics; psychobiotics; ohmic heating; agri-food by-products revalorization; gastrointestinal process simulation

Special Issue Information

Dear Colleagues, 

We are glad to present this Special Issue on Food Science and Nutrition in the International Journal of Environmental Research and Public Health. 

Undoubtedly, food science is linked to nutrition since food is a source of compounds that are biochemically and physiologically transformed by living organisms to obtain energy and build organic macromolecules. Food Science and Nutrition also comprise an equilibrium between diet, health, and disease, including understanding how the transformation of dietary compounds is a tool to enhance the health-derived benefits of bioactive compounds. Depending on the food matrix and industrial or physiological transformations, bioactive compounds exhibit a particular behavior and modulate several metabolic pathways. Considering the plethora of food and food preparations, academia and industry may benefit from research aimed at understanding the complex interactions between food components within the food matrix. This information will allow a better design of nutritious and functional food products. 

This Special Issue aims to publish novel and original research on the conjunction between food science and nutrition, considering in vitro, in vivo, and clinical studies with a major focus on the impact and interaction of the food matrix in nutrition. We welcome contributions in the form of research articles, reviews (literature reviews, mini-reviews, or systematic reviews), or meta-analyses considering topics such as: 

  • Molecular mechanisms of food components within a food matrix.
  • Bioaccessibility, bioavailability, and bioactivity of food components and their relationship with nutrition.
  • Impact of food components in a food matrix in models of disease.
  • The effect of food technologies on the transformation of food components and their impact on nutrition.

Dr. Ivan Luzardo-Ocampo
Dr. Diego A. Luna-Vital
Dr. Aurea Ramírez-Jiménez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioavailability
  • bioactivity
  • bioaccessibility
  • bioactive compounds
  • dietary components
  • food science
  • food technology
  • food matrix
  • nutrition

Published Papers (4 papers)

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Research

21 pages, 17197 KiB  
Article
Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism
by Ana María Sotelo-González, Rosalía Reynoso-Camacho, Ana Karina Hernández-Calvillo, Ana Paola Castañón-Servín, David Gustavo García-Gutiérrez, Haiku Daniel de Jesús Gómez-Velázquez, Miguel Ángel Martínez-Maldonado, Ericka Alejandra de los Ríos and Iza Fernanda Pérez-Ramírez
Int. J. Environ. Res. Public Health 2023, 20(5), 4418; https://doi.org/10.3390/ijerph20054418 - 1 Mar 2023
Cited by 1 | Viewed by 2144
Abstract
There is an increasing interest in developing natural herb-infused functional beverages with health benefits; therefore, in this study, we aimed to evaluate the effect of strawberry, blueberry, and strawberry-blueberry blend decoction-based functional beverages on obesity-related metabolic alterations in high-fat and high-fructose diet-fed rats. [...] Read more.
There is an increasing interest in developing natural herb-infused functional beverages with health benefits; therefore, in this study, we aimed to evaluate the effect of strawberry, blueberry, and strawberry-blueberry blend decoction-based functional beverages on obesity-related metabolic alterations in high-fat and high-fructose diet-fed rats. The administration of the three berry-based beverages for eighteen weeks prevented the development of hypertriglyceridemia in obese rats (1.29–1.78-fold) and hepatic triglyceride accumulation (1.38–1.61-fold), preventing the development of hepatic steatosis. Furthermore, all beverages significantly down-regulated Fasn hepatic expression, whereas the strawberry beverage showed the greatest down-regulation of Acaca, involved in fatty acid de novo synthesis. Moreover, the strawberry beverage showed the most significant up-regulation of hepatic Cpt1 and Acadm (fatty acid β-oxidation). In contrast, the blueberry beverage showed the most significant down-regulation of hepatic Fatp5 and Cd36 (fatty acid intracellular transport). Nevertheless, no beneficial effect was observed on biometric measurements, adipose tissue composition, and insulin resistance. On the other hand, several urolithins and their derivatives, and other urinary polyphenol metabolites were identified after the strawberry-based beverages supplementation. In contrast, enterolactone was found significantly increase after the intake of blueberry-based beverages. These results demonstrate that functional beverages elaborated with berry fruits prevent diet-induced hypertriglyceridemia and hepatic steatosis by modulating critical genes involved in fatty acid hepatic metabolism. Full article
(This article belongs to the Special Issue Food Science and Human Nutrition)
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13 pages, 3198 KiB  
Article
Eating Behavior and Obesity in a Sample of Spanish Schoolchildren
by Andrea Calderón García, Ana Alaminos-Torres, Roberto Pedrero Tomé, Consuelo Prado Martínez, Jesús Román Martínez Álvarez, Antonio Villarino Marín and María Dolores Marrodán Serrano
Int. J. Environ. Res. Public Health 2023, 20(5), 4186; https://doi.org/10.3390/ijerph20054186 - 26 Feb 2023
Cited by 3 | Viewed by 2456
Abstract
From the point of view of prevention, it is convenient to explore the association between eating behavior and the obese phenotype during school and adolescent age. The aim of the present study was to identify eating behavior patterns associated with nutritional status in [...] Read more.
From the point of view of prevention, it is convenient to explore the association between eating behavior and the obese phenotype during school and adolescent age. The aim of the present study was to identify eating behavior patterns associated with nutritional status in Spanish schoolchildren. A cross-sectional study of 283 boys and girls (aged 6 to 16 years) was carried out. The sample was evaluated anthropometrically by Body Mass Index (BMI), waist-to-height ratio (WHtR) and body fat percentage (%BF). Eating behavior was analyzed using the CEBQ “Children’s Eating Behavior Questionnaire”. The subscales of the CEBQ were significantly associated with BMI, WHtR and %BF. Pro-intake subscales (enjoyment of food, food responsiveness, emotional overeating, desire for drinks) were positively related to excess weight by BMI (β = 0.812 to 0.869; p = 0.002 to <0.001), abdominal obesity (β = 0.543–0.640; p = 0.02 to <0.009) and high adiposity (β = 0.508 to 0.595; p = 0.037 to 0.01). Anti-intake subscales (satiety responsiveness, slowness in eating, food fussiness) were negatively related to BMI (β = −0.661 to −0.719; p = 0.009 to 0.006) and % BF (β = −0.17 to −0.46; p = 0.042 to p = 0.016). Full article
(This article belongs to the Special Issue Food Science and Human Nutrition)
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16 pages, 5595 KiB  
Article
Induction of Apoptosis and Decrease of Autophagy in Colon Cancer Cells by an Extract of Lyophilized Mango Pulp
by Gustavo Argenor Lozano-Casabianca, Sandra Sulay Arango-Varela and María Elena Maldonado-Celis
Int. J. Environ. Res. Public Health 2023, 20(5), 4165; https://doi.org/10.3390/ijerph20054165 - 25 Feb 2023
Viewed by 1896
Abstract
Previous studies have indicated that mango fruit has a chemopreventive capacity against colorectal cancer cells. The objective of this research was to evaluate the effect of an aqueous extract of lyophilized mango pulp (LMPE) on colon adenocarcinoma cells (SW480) and their metastatic derivatives [...] Read more.
Previous studies have indicated that mango fruit has a chemopreventive capacity against colorectal cancer cells. The objective of this research was to evaluate the effect of an aqueous extract of lyophilized mango pulp (LMPE) on colon adenocarcinoma cells (SW480) and their metastatic derivatives (SW620) death and cellular invasion. DNA fragmentation was assessed by TUNEL assay; autophagy and expression of DR4 and Bcl-2 by flow cytometry; the expression of 35 apoptosis-related proteins and of matrix metalloproteinases 7 and 9 by immunodetection; and the invasive capacity of the cells by Boyden chamber. The results showed that LMPE at 30 mg/mL and 48 h of exposure results in DNA fragmentation and apoptosis in SW480 (p < 0.001) and SW620 (p < 0.01) cells. Additionally, LMPE decreased autophagy in the SW480 and SW620 cell lines (p < 0.001), which could sensitize them to the DNA damage generated by LMPE. The LMPE did not modulate the expression of matrix metalloproteinases 7 and 9, nor did it affect cellular invasion processes in the SW480 and SW620 cell lines. In conclusion, LMPE induces apoptosis and decreases autophagy in SW480 and SW620 cells. Full article
(This article belongs to the Special Issue Food Science and Human Nutrition)
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16 pages, 2514 KiB  
Article
Serum Phospholipids Are Potential Therapeutic Targets of Aqueous Extracts of Roselle (Hibiscus sabdariffa) against Obesity and Insulin Resistance
by Carmen Alejandra Rangel-García, Rosalía Reynoso-Camacho, Iza F. Pérez-Ramírez, Elizabeth Morales-Luna, Ericka A. de los Ríos and Luis M. Salgado
Int. J. Environ. Res. Public Health 2022, 19(24), 16538; https://doi.org/10.3390/ijerph192416538 - 9 Dec 2022
Cited by 1 | Viewed by 1409
Abstract
Roselle (Hibiscus sabdariffa) is rich in phenolic compounds with antiobesogenic and antidiabetic effects. In this study, the effects of aqueous extracts of two varieties of Hibiscus sabdariffa, Alma blanca (white-yellow color) and Cuarenteña (purple color), were evaluated for the prevention [...] Read more.
Roselle (Hibiscus sabdariffa) is rich in phenolic compounds with antiobesogenic and antidiabetic effects. In this study, the effects of aqueous extracts of two varieties of Hibiscus sabdariffa, Alma blanca (white-yellow color) and Cuarenteña (purple color), were evaluated for the prevention of obesity and insulin resistance in rats fed a high-fat and high-fructose diet (HFFD), identifying targeted molecules through global metabolomics. After sixteen weeks, both roselle aqueous extracts prevented body weight gain, and white roselle extract ameliorated insulin resistance and decreased serum free fatty acid levels. Moreover, white roselle extract decreased 18:0 and 20:4 lysophosphatidylethanolamines and purple roselle extract increased 16:0 and 20:4 lysophosphatidylinositol compared to HFFD-fed rats. These results demonstrate that roselle’s beneficial health effects are variety-dependent. Interestingly, the white roselle extract showed a greater beneficial effect, probably due to its high contents of organic and phenolic acids, though its consumption is not as popular as that of the red/purple varieties. Full article
(This article belongs to the Special Issue Food Science and Human Nutrition)
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