Hemorrhagic Fever Viruses Infection

A special issue of Infectious Disease Reports (ISSN 2036-7449).

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 3429

Special Issue Editor


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Guest Editor
Viral Special Pathogens Branch, Division of High-Consequence Pathogens & Pathologies, National Center for Emerging and Zoonotic Infectious Diseases, US Centers for Disease Control & Prevention, Galveston, TX 77555, USA
Interests: ecology; evolution; epidemiology of high-consequence pathogens

Special Issue Information

Dear Colleagues,

Hemorrhagic fever viruses (HFV) are a group of high-consequence viral pathogens which can lead to multisystem syndromic disease characterized by acute febrile illness, bleeding disorders, and can progress to shock and death.  While many HFVs cause relatively mild illness, some, such as Ebola virus disease can lead to multi-year and widespread outbreaks with high case-fatality rates. Other examples of HFV include Marburg virus, Rift Valley fever virus, Hantaviruses, Congo hemorrhagic fever virus, Alkhumra virus, South American Hemorrhagic fever viruses (Chapare, Guanarito, Junin, Machupo, Sabia viruses, etc.) Kyasanur Forest disease virus, Omsk hemorrhagic fever, and New World Arenaviruses such as Lujo and Lassa virus.  While several key research efforts have revealed answers to HFV pathogenesis, much remains to be learned about how many of these agents aid in the understanding of their ecology, evolution, and epidemiology for future mitigation and countermeasure strategies.

This Special Issue will cover a wide range of topics focusing on viruses that cause hemorrhagic fever and aims to enhance current knowledge of these viruses, host-response, ecological hosts, and the resultant diseases or mitigation of disease.  All types of articles will be considered for publication, including short reports, primary research articles, as well as reviews.

We look forward to your contributions!

Yours Sincerely,
Dr. Sergio E. Rodriguez
Guest Editor

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Keywords

  • HFV
  • VHF
  • viral hemorrhagic fever virus
  • virus-host interactions
  • virulence factors
  • viral pathogenesis
  • viral transmission
  • arboviral disease
  • immune activation and evasion
  • adaptive immunity
  • therapeutics
  • vaccines
  • animal models
  • viral ecology
  • viral epidemiology
  • filovirus
  • arenavirus
  • bunyavirus
  • hantavirus
  • flavivirus

Published Papers (1 paper)

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Research

7 pages, 468 KiB  
Article
Study of Dengue Virus Transovarial Transmission in Aedes spp. in Ternate City Using Streptavidin-Biotin-Peroxidase Complex Immunohistochemistry
by Nia Kurnia, Yance Kaitana, Christina Leta Salaki, Lucia Cecilia Mandey, Josef Sem Berth Tuda and Trina Ekawati Tallei
Infect. Dis. Rep. 2022, 14(5), 765-771; https://doi.org/10.3390/idr14050078 - 28 Sep 2022
Cited by 4 | Viewed by 2824
Abstract
Aedes aegypti is the most dominant vector in the transmission of dengue hemorrhagic fever (DHF). In addition to Ae. aegypti, Ae. albopictus is a secondary vector of the dengue virus, and both species are widespread in Indonesia. The dengue virus is transmitted [...] Read more.
Aedes aegypti is the most dominant vector in the transmission of dengue hemorrhagic fever (DHF). In addition to Ae. aegypti, Ae. albopictus is a secondary vector of the dengue virus, and both species are widespread in Indonesia. The dengue virus is transmitted from person to person through the bite of an Aedes spp. The vertical (transovarial) transmission of the dengue virus from infective female mosquitoes to their offspring is one of the means by which the dengue virus maintains its existence in nature. Transovarial dengue virus transmission in Aedes spp. mosquitoes contributes to the spread and maintenance of the dengue epidemic. This study employed a qualitative survey to detect dengue virus transovarial transmission in Ternate using the streptavidin-biotin-peroxidase complex (ISBPC) immunohistochemical test. The ISBPC examination of samples collected from the four subdistricts in Ternate revealed a positive result for transovarial transmission of dengue virus. Four Aedes spp., including two Ae. aegypti females, one Ae. albopictus female, and one Ae. albopictus male, tested positive for transovarial transmission of dengue virus in the district of North Ternate. Four Aedes spp., including three Ae. aegypti females and one Ae. aegypti male, were found to be positive for the transovarial transmission of dengue virus in the Central Ternate district. Seven Aedes spp., including five Ae. aegypti females, one Ae. aegypti male, and one Ae. albopictus female, tested positive for transovarial transmission of the dengue virus in the district of South Ternate city. One Ae. aegypti male showed positive results for transovarial transmission of dengue virus in the Ternate Island District. In this study, the transovarial transmission of the dengue virus occurred in both Aedes spp. female and male mosquitoes. It was demonstrated that Aedes spp. carry the dengue virus in their ovaries and can pass it on to their offspring. As a result, the cycle of passing the dengue virus on to local mosquito populations in the city of Ternate is not going to end just yet. Full article
(This article belongs to the Special Issue Hemorrhagic Fever Viruses Infection)
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