Recent Advances in Peripheral Artery Disease

A special issue of Hearts (ISSN 2673-3846).

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 3393

Special Issue Editor


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Guest Editor
Department of Cardiovascular Medicine, Fondazione Policlinico, Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy
Interests: molecular and cellular mechanisms of angiogenesis and vasculogenesis; use of angiogenic growth factors for therapeutic angiogenesis and tissue regeneration; diabetes complications; genetics of cardiovascular and neurodegenerative diseases

Special Issue Information

Dear Colleagues,

Peripheral artery disease (PAD) is an increasingly important clinical problem. Years after its first description, it is now clear that PAD is not a simple complication of other diseases such as diabetes or arterial hypertension, but an independent and relevant cardiovascular risk factor. In addition to its effect on patients, PAD can have a significant impact on healthcare systems as it increases with age and leads to cardiovascular complications. The quality of life and survival rate of patients with PAD are low compared to other patients. Unfortunately, until recently, all available data on designing treatments for patients with PAD were overshadowed by studies conducted in other patient populations and other outcomes. Opportunely, PAD has been the focus of many high-quality studies in recent years, and more useful and valid data are available for the treatment of this severe disease.

The purpose of this Special Issue is to collect original research studies and literature reviews that will provide a better understanding of PAD and newer treatment strategies.

Dr. Federico Biscetti
Guest Editor

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Keywords

  • peripheral artery disease (PAD)
  • critical limb threatening ischemia (CLTI)
  • cardiovascular complications of diabetes
  • type 2 diabetes mellitus
  • biomarkers

Published Papers (1 paper)

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8 pages, 757 KiB  
Case Report
Conversion of Femoral-Tibial Bypass Surgery into Deep Vein Arterialization in a Patient with Severe Peripheral Artery Disease: Post-Operative Computed Tomography and Angiography Findings
by Marco Parillo, Domenico De Stefano, Vincenzo Catanese, Carlo Augusto Mallio, Francesco Spinelli, Francesco Stilo and Carlo Cosimo Quattrocchi
Hearts 2023, 4(1), 12-19; https://doi.org/10.3390/hearts4010002 - 09 Jan 2023
Cited by 1 | Viewed by 2777
Abstract
Deep vein arterialization (DVA) is a therapeutic option in “no option” for revascularization chronic limb-threatening ischemia patients, creating an arteriovenous bypass between a proximal artery and a distal deep venous target at the ankle. Imaging plays a crucial role in peripheral arterial disease [...] Read more.
Deep vein arterialization (DVA) is a therapeutic option in “no option” for revascularization chronic limb-threatening ischemia patients, creating an arteriovenous bypass between a proximal artery and a distal deep venous target at the ankle. Imaging plays a crucial role in peripheral arterial disease (PAD) patient management. We present the case of a 71-year-old PAD patient (Rutherford class 5) with focal gangrene of the first and second toes of the right foot, who was admitted to the vascular surgery department to undergo revascularization surgery by femoro-tibial artery bypass. During surgery a DVA was performed because of an unsatisfactory distal artery target. The post-operative computed tomography angiography showed the saphenous graft patency and opacification of distal foot veins. Subsequent angiography documented the presence of a large venous collateral, responsible for extensive early wash-out to leg venous vessels, which was then embolized. After two months, the patient underwent amputation of the right first and second necrotic toes at the level of the metatarsophalangeal joints. The post-operative course was excellent, with disappearance of pain at rest and good trophism of the surgical wound. Full article
(This article belongs to the Special Issue Recent Advances in Peripheral Artery Disease)
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