Prevention, Intervention, and Care of Dementia

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 3531

Special Issue Editor

Laboratory of Medical Physics, Department of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece
Interests: neurology; medical physics; epilepsy; Parkinson; multiple sclerosis; autism; Altzheimer; neural net models and in chaos theory; pico-Tesla Transcranial magnetic stimulation to patients with CNS disorders

Special Issue Information

Dear Colleagues,

Dementia is a dementing disorder with prominent neuropsychiatric features, associated with degeneration of cortical neurons, particularly in the entorhinal anterior cingulated, insular, temporal, and frontal regions. The most common syndrome is the behavioral disorder of frontotemporal dementia, in which there is bilateral atrophy of the frontal and anterior temporal lobes. Other distinctive syndromes are progressive non-fluent aphasia, in which there is asymmetric involvement of the left anterior hemisphere and semantic occurring in association with circumscribed atrophy of the temporal lobes. In this issue, we invite you to attempt to highlight the causes and describe methods for prevention and intervention and care of dementia considering the abovementioned disorders.

Prof. Dr. Photios Anninos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dementia
  • prevention
  • intervention

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

9 pages, 644 KiB  
Article
Effectiveness of a Program Based on Action-Observation Training (AOT) on Motor, Functional and Cognitive Aspects in Patients with Cognitive Impairment: A Non-Randomized Controlled Trial
by Cecilia Estrada-Barranco, Maria de los Ángeles Martinez-Javaloyes, Isabel Rodriguez-Costa, Ismael Sanz-Esteban, Alberto Bermejo-Franco, Araceli Aranda-Ruiperez and Maria de los Ángeles Gallegos-Martínez
Healthcare 2023, 11(7), 1030; https://doi.org/10.3390/healthcare11071030 - 04 Apr 2023
Cited by 1 | Viewed by 1647
Abstract
Cognitive impairment is frequent in elderly subjects. It is associated with motor impairment, a limitation in quality of life and frequently, institutionalization. The aim of this work is to test the efficacy of a therapeutic group program based on action-observation learning. Methods: a [...] Read more.
Cognitive impairment is frequent in elderly subjects. It is associated with motor impairment, a limitation in quality of life and frequently, institutionalization. The aim of this work is to test the efficacy of a therapeutic group program based on action-observation learning. Methods: a non-randomized controlled trial study was conducted. We included 40 patients with cognitive impairment from a nursing home who were categorized into mild and moderate cognitive impairment and divided separately into a control and experimental group. Experimental group performed a 4-week group work, in which each patient with mild cognitive impairment was paired with a patient with moderate cognitive impairment. Thus, patients with mild cognitive impairment observed a series of functional exercises performed by their peers and replicated them. Simultaneously, the patients with moderate cognitive impairment replicated the movement after observing it performed by a patient with mild cognitive impairment. The control group continued to receive their usual care at the center. The upper limb function, cognitive level and function in basic activities of human daily life were measured before and after the intervention and compared with the control group. Results: statistically significant differences were found in the functionality of basic activities of daily living, in the functionality of the upper limb and in the cognitive level in all patients in the experimental group regardless of the initial cognitive level. No statistically significant differences were found in the control group. Conclusions: the implementation of a group, peer-based, action-observation learning therapeutic program is effective in improving the basic activities of human daily life, cognitive level and upper limb functionality in patients with mild and moderate dementia. Full article
(This article belongs to the Special Issue Prevention, Intervention, and Care of Dementia)
Show Figures

Figure 1

13 pages, 2696 KiB  
Article
Fitting Contralateral Neuroanatomical Asymmetry into the Amyloid Cascade Hypothesis
by Fernando Arreola, Benjamín Salazar and Antonio Martinez
Healthcare 2022, 10(9), 1643; https://doi.org/10.3390/healthcare10091643 - 29 Aug 2022
Cited by 1 | Viewed by 1454
Abstract
Alzheimer’s Disease (AD) is the most common cause of dementia. Due to the progressive nature of the neurodegeneration associated with the disease, it is of clinical interest to achieve an early diagnosis of AD. In this study, we analyzed the viability of asymmetry-related [...] Read more.
Alzheimer’s Disease (AD) is the most common cause of dementia. Due to the progressive nature of the neurodegeneration associated with the disease, it is of clinical interest to achieve an early diagnosis of AD. In this study, we analyzed the viability of asymmetry-related measures as potential biomarkers to facilitate the early diagnosis of AD. These measures were obtained from MAPER-segmented MP-RAGE MRI studies available at the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database, and by analyzing these studies at the level of individual segmented regions. The temporal evolution of these measures was obtained and then analyzed by generating spline regression models. Data imputation was performed where missing information prevented the temporal analysis of each measure from being realized, using additional information provided by ADNI for each patient. The temporal evolution of these measures was compared to the evolution of other commonly used markers for the diagnosis of AD, such as cognitive function, concentrations of Phosphorylated-Tau, Amyloid-β, and structural MRI volumetry. The results of the regression models showed that asymmetry measures, in particular regions such as the parahippocampal gyrus, differentiated themselves temporally before most of the other evaluated biomarkers. Further studies are suggested to corroborate these results. Full article
(This article belongs to the Special Issue Prevention, Intervention, and Care of Dementia)
Show Figures

Figure 1

Back to TopTop