Special Issue "Aging Microenvironment Promotes Disease Development"

A special issue of Geriatrics (ISSN 2308-3417).

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 174

Special Issue Editors

Laboratory of Cardiovascular and Aging Research, Department of Endocrinology, Metabolism, and Cardiovascular System, Faculty of Science and Medicine, University of Fribourg, Rue du musée 5, 1700 Fribourg, Switzerland
Interests: aging; arginase; cardiovascular disease; fibrosis; hypoxia; inflammation; macrophage; mitochondrial oxidative stress; senescence
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Hongyu Qiu
E-Mail Website
Guest Editor
Center for Molecular and Translational Medicine, Institute of Biomedical Science, Georgia State University, Atlanta, GA 30303, USA
Interests: molecular cardiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The aging population is growing steadily in our society. Aging is highly associated with chronic diseases including cardiovascular disease, renal disease, metabolic disease, neurodegenerative disease, cancer, etc. Organ failure in aging is accompanied by tissue degeneration and remodeling, which is attributable to an aging microenvironment in tissues/organs, including elevated chronic inflammation, oxidative stress, cellular senescence, increased vulnerability to cell death, fibrosis, etc. These mechanisms are often shared by chronic diseases in younger age and accelerated by the aging process. Therefore, understanding the origin and molecular mechanisms of the aging microenvironment formation has a great impact on the identification of new and specific therapeutic targets for chronic diseases and also on delaying organ failure associated with aging, which ultimately leads to the extension of a healthy lifespan.

In this Special Issue, entitled “Aging Microenvironment Promotes Disease Development”, we will collect advances in research on understanding the molecular and cellular link of organismal aging and organ failure. Possible novel targets of delaying organismal aging and organ failure will be discussed. We would like to invite scientists to submit manuscripts focusing on the modification of the aging microenvironment in tissues/organs to improve healthy lifespan and age-associated organ failure, including cardiovascular aging, renal aging, brain aging, and cancer development in aging. Contributions to this Special Issue will be invited in the format of reviews, research articles, communications, and concept papers.

You may choose our Joint Special Issue in Biomolecules.

Prof. Dr. Zhihong Yang
Prof. Dr. Hongyu Qiu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Geriatrics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cell-cell interaction
  • cytokines
  • fibrosis
  • inflammation
  • macrophages
  • mitochondrial dysfunction
  • senescence

Published Papers

There is no accepted submissions to this special issue at this moment.
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