Special Issue "Genetics and Genomics of Addiction"
Deadline for manuscript submissions: closed (15 October 2022) | Viewed by 14850
With the opioid epidemic occurring during the global COVID-19 pandemic, substance use disorder (SUD) has been on the rise. Thankfully addiction can be treated and managed, but we have a limited armamentarium. Our current research on the genetic susceptibility to addiction contributes to our understanding of the mechanisms that underlie SUD. These mechanisms lie at the heart of the development of novel pharmacotherapies to facilitate the treatment of SUD.
The aim of this Special Issue is to bring together researchers of substance use disorder across various drugs of abuse and experimental systems to describe the current status of addiction genetics. Psychiatric disorders are known to be complex traits due to their polygenic nature. Substance use disorder is unique in that the progression to disease requires an exposure to an environmental factor, a drug. Sequenced genomes, new animal model resources, and GWAS of large sample sizes have made vast inroads into our understanding of the genetics that underlie addiction. Future mechanistic studies will be driven by integrating big data produced across animal models and human studies to identify their consilient features. This issue will cover topics related to genes, genetics and genomics of addiction, including but not limited to: human genetics, systems genetics, gene expression, -omics, bioinformatics, cross-species analysis, animal models, genetic mapping, candidate gene studies, GxE. We welcome researchers from across the world to contribute their high-quality manuscripts covering all the aspects related to the genetics of addiction. In this Special Issue, both original articles and reviews are welcome.
Dr. Jason Bubier
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Drug abuse
- Human genetics
- Systems genetics
- Gene expression
- Cross-species analysis
- Animal models
- Genetic mapping