Genetics and Proteogenomics of Kinetoplastids
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Microbial Genetics and Genomics".
Deadline for manuscript submissions: closed (20 December 2022) | Viewed by 2586
Special Issue Editor
Interests: Leishmania; Trypanosoma; heat shock proteins; RNA binding proteins; regulation of gene expression; genomics; transcriptomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are proud to announce the opening of a second volume dealing with the genetics and genomics of kinetoplastids, following the great success of the previous volume and the interest it attracted among researchers working in the field of these astonishing microorganisms. You can access the contributions appearing in the first volume at https://www.mdpi.com/books/pdfview/book/4005
Kinetoplastid protists belong to the Euglenozoa phylum and represent one of the earliest extant branches of eukaryotic lineage. This is one of the most successful groups of live beings. Apart from the trypanosomatids causing human diseases (e.g., Trypanosoma ssp., causing Chagas disease and sleeping sickness in humans, and Leishmania spp., causing kala-azar and other leishmaniases), many parasites for plants (Phytomonas spp.) and insects (Leptomonas, Angomonas, Crithidia, and other genera) also belong to this class. In addition, free-living kinetoplastids (Bodo spp.) are abundant and active microbial predators in terrestrial and aquatic ecosystems.
In recent years, the incorporation of “omics” methodologies to the study of these organisms has allowed the assembly of genomes for a growing number of both parasitic and free-living kinetoplastids to analyze changes in gene expression, determine the proteome compendium, establish metabolic pathways, and so on. Therefore, a vast amount of genetics and genomics data are being generated that will contribute to increasing our knowledge on the peculiar aspects of cytology, genome organization, and mechanisms of gene regulation that this group of organisms have evolved since their ancient evolutionary origin.
The aim of this Special Issue is to bring together a set of reviews and research articles addressing aspects such as genome organization, mechanisms of gene expression, specific metabolic pathways, evolutionary relationships and databases, among others, focused on any species belonging to this group of protists.
Dr. Jose María Requena
Guest Editor
Manuscript Submission Information
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Keywords
- kinetoplastids
- genome assembly and annotation
- transcriptomics and regulation and gene expression
- proteomics
- metabolomics
- phylogenetics
- databases and web resources
- mechanisms of drug resistance
- virulence factors
