RNA in Extracellular Vesicles
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 4068
Special Issue Editors
Interests: extracellular vesicles; extracellular RNA; astrocyte-derived extracellular vesicles; ncRNA; miRNA; mRNA; human sweat nucleic acids; metagenomics
Special Issues, Collections and Topics in MDPI journals
Interests: extracellular vesicles; transcriptomics; RNA; mRNA; small RNA; liquid biopsies; kidney disease; diabetes; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular Vesicle (EV) RNA cargo attracts a lot of interest as a liquid biopsy offering a way to tap information about the originating tissues and physiological status of the secreting cells. EV RNA is also investigated as a dynamic intercellular or interkingdom messenger. Consequently, the EV RNA field progresses at a fast pace with regular new twists due to technical advances and challenges. For example, RNA is now recognized both inside vesicles as a protected cargo as well as bound to the surface of EV. EV have been traditionally classified based on secretion pathways: endosomal pathway or membrane budding, which may result in the packaging of different RNA species. Currently investigators explore also novel types of secreted nanoparticles such as exomeres and supermeres with potentially different RNA cargo than found from EV secreted from the same cells. In addition to its use as liquid biopsy, EV RNA may be able to modulate gene expression if taken up by cells. The purpose of this Special Issue is to present original research, critical technologies and review articles documenting different RNA types in EV and nanoparticles and their regulatory roles in recipient cells.
Dr. Genevieve Bart
Dr. Maija Puhka
Guest Editors
Manuscript Submission Information
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Keywords
- EV associated RNA
- EV encapsulated RNA
- novel RNA
- regulatory RNA
- ncRNA
- mRNA
- small RNA
- miRNA
- transcriptomics
- PCR
