Special Issue "Microbiome Analysis Techniques and Discovery"

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Microbial Genetics and Genomics".

Deadline for manuscript submissions: closed (25 June 2023) | Viewed by 122

Special Issue Editors

Diversigen, 600 County Rd D West Suite 8, New Brighton, MN 55112, USA
Interests: microbiome; multiomics; metagenomics; next-generation sequencing; host-microbe interactions; data integration
Diversigen, 600 County Rd D West Suite 8, New Brighton, MN 55112, USA
Interests: statistical analysis of microbiome and multiomic datasets; microbial ecology; microbiome and host interactions; microbiome in health and disease

Special Issue Information

Dear Colleagues,

Over the past two decades, studies into the composition and potential function of microbial communities have been intensively explored in diverse systems. With the advent of next-generation sequencing technologies and advances in computation, the ability to deeply sequence and analyze large, complex datasets has improved exponentially. As a result, major insights into the structure, diversity and function of microbial communities across diverse ecosystems have been reported.

Microbial communities have now been implicated in diverse ecological functions. For example, in human and animal health and disease, they have been implicated in immune system modulation, numerous disease states, protection against pathogens, drug metabolism, maintenance of mucosal barriers, and assistance in dietary energy extraction. Similarly, in environmental systems, microbes and microbial communities are responsible for global carbon and nutrient cycling in both terrestrial and aquatic contexts.

Despite substantial efforts to characterize the microbiomes of diverse systems, much work remains to be conducted to precisely understand the role of individual members of these communities in their respective environments. Moreover, a detailed understanding of the complex interactions between microbes in these communities and the effects of those interactions is needed. Finally, there is a continued need for bioinformatic tools incorporating robust statistical techniques in order to appropriately analyze these complex datasets and to integrate the many types of multiomic datasets for improved insights.

In this Special Issue of Genes, we welcome contributions that aid in furthering our understanding of the crucial role that microbiomes play across broad ecosystems. One example might be work that aims to characterize the specific role(s) of members of complex microbial communities and their potential effects on their broader ecological contexts (both host and non-host). Similarly, another example would be work that aims to integrate multiomic datasets (i.e., metagenomic, metatranscriptomic, metabolomic and/or proteomic) towards a cohesive understanding of microbiome dynamics in experimental systems. A final example would be work that describes novel tools for the processing and/or statistical analysis of multiomic data.

Dr. Tonya Ward
Dr. Alex La Reau
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • microbiome
  • microbial ecology
  • next-generation sequencing
  • bioinformatics
  • metatranscriptomics
  • metabolomics
  • multiomics

Published Papers

There is no accepted submissions to this special issue at this moment.
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