23 February 2023
Genes | Editor’s Choice Articles

The Editor’s Choice Articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles that have recently been published in the journal that they believe will be particularly interesting to authors, or important in this field. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

We are pleased to present the Editor’s Choice Articles published in Genes (ISSN: 2073-4425), and we hope that these papers can help and provide a reference for your academic research. A carefully curated list of high-quality articles can be found below.

1. “Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae
by Tania Jordá and Sergi Puig
Genes 2020, 11(7), 795;
Available online:

2. “Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability”
by Giorgio Milazzo, Daniele Mercatelli, Giulia Di Muzio, Luca Triboli, Piergiuseppe De Rosa, Giovanni Perini and Federico M. Giorgi
Genes 2020, 11(5), 556;
Available online:

3. “Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations”
by Dragan Primorac, Vilim Molnar, Eduard Rod, Željko Jeleč, Fabijan Čukelj, Vid Matišić, Trpimir Vrdoljak, Damir Hudetz, Hana Hajsok and Igor Borić
Genes 2020, 11(8), 854;
Available online:

4. “Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas
by Jorge Lalucat, Magdalena Mulet, Margarita Gomila and Elena García-Valdés
Genes 2020, 11(2), 139;
Available online:

5. “Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy”
by Jac A. Nickoloff, Neelam Sharma and Lynn Taylor
Genes 2020, 11(1), 99;
Available online:

6. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589;
Available online:

7. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010;
Available online:

8. “Transcriptional Factors Regulate Plant Stress Responses Through Mediating Secondary Metabolism”
by Tehseen Ahmad Meraj, Jingye Fu, Muhammad Ali Raza, Chenying Zhu, Qinqin Shen, Dongbei Xu and Qiang Wang
Genes 2020, 11(4), 346;
Available online:

9. “Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response”
by Radhakrishnan Vishnubalaji, Hibah Shaath and Nehad M. Alajez
Genes 2020, 11(7), 760;
Available online:

10. “Regulation of mTORC2 Signaling”
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045;
Available online:

11. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295;
Available online:

12. “Down Regulation and Loss of Auxin Response Factor 4 Function Using CRISPR/Cas9 Alters Plant Growth, Stomatal Function and Improves Tomato Tolerance to Salinity and Osmotic Stress”
by Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni et al.
Genes 2020, 11(3), 272;
Available online:

13. “Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts”
by Roman Matyášek and Aleš Kovařík
Genes 2020, 11(7), 761;
Available online:

14. “Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium”
by Jonathan Tak-Sum Chow and Leonardo Salmena
Genes 2020, 11(9), 1002;
Available online:

15. “A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma”
by Zilong Bian, Rong Fan and Lingmin Xie
Genes 2022, 13(5), 851;
Available online:

16. “Plasmid Transfer by Conjugation in Gram-Negative Bacteria: From the Cellular to the Community Level”
by Chloé Virolle, Kelly Goldlust, Sarah Djermoun, Sarah Bigot and Christian Lesterlin
Genes 2020, 11(11), 1239;
Available online:

17. “Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors”
by Duran Sürün, Aksana Schneider, Jovan Mircetic, Katrin Neumann, Felix Lansing, Maciej Paszkowski-Rogacz, Vanessa Hänchen, Min Ae Lee-Kirsch and Frank Buchholz
Genes 2020, 11(5), 511;
Available online:

18. “Genetic Modifiers and Rare Mendelian Disease”
by K. M. Tahsin Hassan Rahit and Maja Tarailo-Graovac
Genes 2020, 11(3), 239;
Available online:

19. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120;
Available online:

20. “The AP2/ERF Gene Family in Triticum durum: Genome-Wide Identification and Expression Analysis under Drought and Salinity Stresses”
by Sahar Faraji, Ertugrul Filiz, Seyed Kamal Kazemitabar, Alessandro Vannozzi, Fabio Palumbo, Gianni Barcaccia and Parviz Heidari
Genes 2020, 11(12), 1464;
Available online:

We would like to take this opportunity to thank all of the research groups that submitted manuscripts to Genes. We would appreciate it if you could circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest:

Submitting a Manuscript:
Genes is an open access journal that publishes spotlights, reviews, original research contributions, and short communications. Papers may be submitted via the following link:

Launching a Special Issue:
You have the opportunity to propose hot topics and edit a Special Issue together with experts in the field. More information can be found at the following link:

Joining the Editorial Board:
If you are an active researcher in the field of genetics and are interested in joining the Editorial Board, please do not hesitate to get in touch (

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