Conference: 19^th Annual International Conference of the Metabolomics Society

Date: 18–22 June 2023

Place: Niagara Falls Convention Centre, 6815 Stanley Avenue, Niagara Falls, Ontario, Canada L2G 3Y9

Booth: #T12

MDPI will be attending the 19^th Annual International Conference of the Metabolomics Society, which will be held from 18 to 22 June 2023 in downtown Niagara Falls, Canada, at the Niagara Falls Convention Centre.

The conference is the official annual meeting of the Metabolomics Society, and the largest metabolomics meeting worldwide. It will cover the major scientific themes of: technology advances; computational metabolomics, statistics, and bioinformatics; metabolomics in health and disease; and metabolomics of plants, food, environment and microbes. A special theme for this conference will focus on mental health, drug addiction and medicinal cannabis. The scientific program will include plenary and keynote talks, three parallel scientific sessions, interactive poster sessions, sponsor lunches, other networking events and a specially organized parallel session to promote metabolomics research in industry. A strong line-up of both introductory and advanced workshops will take place on Sunday, 18 June, and the morning of Monday, 19 June. To complement the exciting scientific program, the conference will offer a welcome reception, vibrant early career events, a conference dinner and other engaging social activities.

The following MDPI journals will be represented:

• Metabolites;
• Agronomy;
• Antioxidants;
• Applied Biosciences;
• BioMed;
• BioMedInformatics;
• Biomolecules;
• Cancers;
• Cells;
• Children;
• CIMB;
• Diseases;
• Foods;
• Genes;
• JPM;
• Nutrients;
• Plants.

Please do not hesitate to reach out (metabolites@mdpi.com) if you plan on attending this conference. Our delegates look forward to meeting you in person and answering any questions that you might have.

For more information about the conference, please visit the following website: https://www.metabolomics2023.org/.

1. “Genome-Wide Analysis of Potassium Channel Genes in Rice: Expression of the OsAKT and OsKAT Genes under Salt Stress”
by Zahra Musavizadeh, Hamid Najafi-Zarrini, Seyed Kamal Kazemitabar, Seyed Hamidreza Hashemi, Sahar Faraji, Gianni Barcaccia and Parviz Heidari
Genes 2021, 12(5), 784; https://doi.org/10.3390/genes12050784
Available online: https://www.mdpi.com/2073-4425/12/5/784

2. “HD-ZIP Gene Family: Potential Roles in Improving Plant Growth and Regulating Stress-Responsive Mechanisms in Plants”
by Rahat Sharif, Ali Raza, Peng Chen, Yuhong Li, Enas M. El-Ballat, Abdur Rauf, Christophe Hano and Mohamed A. El-Esawi
Genes 2021, 12(8), 1256; https://doi.org/10.3390/genes12081256
Available online: https://www.mdpi.com/2073-4425/12/8/1256

3. “Plants’ Epigenetic Mechanisms and Abiotic Stress”
by Matin Miryeganeh
Genes 2021, 12(8), 1106; https://doi.org/10.3390/genes12081106
Available online: https://www.mdpi.com/2073-4425/12/8/1106

4. “Allelic Diversity at Abiotic Stress Responsive Genes in Relationship to Ecological Drought Indices for Cultivated Tepary Bean, Phaseolus acutifolius A. Gray, and Its Wild Relatives”
by María A. Buitrago-Bitar, Andrés J. Cortés, Felipe López-Hernández, Jorge M. Londoño-Caicedo, Jaime E. Muñoz-Florez, L. Carmenza Muñoz and Matthew Wohlgemuth Blair
Genes 2021, 12(4), 556; https://doi.org/10.3390/genes12040556
Available online: https://www.mdpi.com/2073-4425/12/4/556

5. “Breeding for Resistance to Fusarium Wilt of Tomato: A Review”
by Jessica Chitwood-Brown, Gary E. Vallad, Tong Geon Lee and Samuel F. Hutton
Genes 2021, 12(11), 1673; https://doi.org/10.3390/genes12111673
Available online: https://www.mdpi.com/2073-4425/12/11/1673

6. “Regulation of DNA (de)Methylation Positively Impacts Seed Germination during Seed Development under Heat Stress”
by Jaiana Malabarba, David Windels, Wenjia Xu and Jerome Verdier
Genes 2021, 12(3), 457; https://doi.org/10.3390/genes12030457
Available online: https://www.mdpi.com/2073-4425/12/3/457

7. “Long-Term Waterlogging as Factor Contributing to Hypoxia Stress Tolerance Enhancement in Cucumber: Comparative Transcriptome Analysis of Waterlogging Sensitive and Tolerant Accessions”
by Kinga Kęska, Michał Wojciech Szcześniak, Izabela Makałowska and Małgorzata Czernicka
Genes 2021, 12(2), 189; https://doi.org/10.3390/genes12020189
Available online: https://www.mdpi.com/2073-4425/12/2/189

8. “Understanding Rice-Magnaporthe Oryzae Interaction in Resistant and Susceptible Cultivars of Rice under Panicle Blast Infection Using a Time-Course Transcriptome Analysis”
by Vishesh Kumar, Priyanka Jain, Sureshkumar Venkadesan, Suhas Gorakh Karkute, Jyotika Bhati, Malik Zainul Abdin, Amitha Mithra Sevanthi, Dwijesh Chandra Mishra, Krishna Kumar Chaturvedi, Anil Rai et al.
Genes 2021, 12(2), 301; https://doi.org/10.3390/genes12020301
Available online: https://www.mdpi.com/2073-4425/12/2/301

9. “Down-Regulation of SlGRAS10 in Tomato Confers Abiotic Stress Tolerance”
by Sidra Habib, Yee Yee Lwin and Ning Li
Genes 2021, 12(5), 623; https://doi.org/10.3390/genes12050623
Available online: https://www.mdpi.com/2073-4425/12/5/623

10. “Transcriptome Profiling of Maize (Zea mays L.) Leaves Reveals Key Cold-Responsive Genes, Transcription Factors, and Metabolic Pathways Regulating Cold Stress Tolerance at the Seedling Stage”
by Joram Kiriga Waititu, Quan Cai, Ying Sun, Yinglu Sun, Congcong Li, Chunyi Zhang, Jun Liu and Huan Wang
Genes 2021, 12(10), 1638; https://doi.org/10.3390/genes12101638
Available online: https://www.mdpi.com/2073-4425/12/10/1638

MDPI will be attending the European Human Genetics Conference 2023 (ESHG 2023), held in Glasgow, UK, from 10 to 13 June 2023.

The following MDPI journals will be represented:

• Genes;
• IJMS;
• JPM;
• Applied Biosciences;
• MPs;
• Symmetry;
• Toxics;
• Cells;
• IJNS.

If you plan on attending this conference, feel free to stop by our booth #824. Our delegates look forward to meeting you in person to answer any questions you may have.

For more information about the conference, please visit the following link: https://2023.eshg.org/.

As a leading open access publisher, MDPI provides scholars with a high-quality and rich academic exchange platform by continuously expanding into new and exciting research areas.

In December 2022, MDPI launched five new journals, covering multiple subjects such as life sciences, biology, medicine and pharmacology, social sciences and humanities. These new journals are being edited by established scholars across the world.

If you are interested in creating more open access journals with us to publish cutting-edge research, please send your journal proposal application to newjournal-committee@mdpi.com.

MDPI is pleased to announce that we now display the co-authors’ email addresses in addition to the corresponding author’s email address on the webpage of published papers, protected by Captcha. For more information about this change, please visit the journal’s instructions for authors page. 

We believe this change will facilitate academic discussions and advance our cause of open science and research. The corresponding authors are responsible for communicating with their co-authors and indicating in our system (https://susy.mdpi.com/) if co-authors would prefer for their email addresses not to be displayed.

The Editor’s Choice Articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles that have recently been published in the journal that they believe will be particularly interesting to authors, or important in this field. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

We are pleased to present the Editor’s Choice Articles published in Genes (ISSN: 2073-4425), and we hope that these papers can help and provide a reference for your academic research. A carefully curated list of high-quality articles can be found below.

1. “Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae”
by Tania Jordá and Sergi Puig
Genes 2020, 11(7), 795; https://doi.org/10.3390/genes11070795
Available online: https://www.mdpi.com/2073-4425/11/7/795

2. “Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability”
by Giorgio Milazzo, Daniele Mercatelli, Giulia Di Muzio, Luca Triboli, Piergiuseppe De Rosa, Giovanni Perini and Federico M. Giorgi
Genes 2020, 11(5), 556; https://doi.org/10.3390/genes11050556
Available online: https://www.mdpi.com/2073-4425/11/5/556

3. “Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations”
by Dragan Primorac, Vilim Molnar, Eduard Rod, Željko Jeleč, Fabijan Čukelj, Vid Matišić, Trpimir Vrdoljak, Damir Hudetz, Hana Hajsok and Igor Borić
Genes 2020, 11(8), 854; https://doi.org/10.3390/genes11080854
Available online: https://www.mdpi.com/2073-4425/11/8/854

4. “Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas”
by Jorge Lalucat, Magdalena Mulet, Margarita Gomila and Elena García-Valdés
Genes 2020, 11(2), 139; https://doi.org/10.3390/genes11020139
Available online: https://www.mdpi.com/2073-4425/11/2/139

5. “Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy”
by Jac A. Nickoloff, Neelam Sharma and Lynn Taylor
Genes 2020, 11(1), 99; https://doi.org/10.3390/genes11010099
Available online: https://www.mdpi.com/2073-4425/11/1/99

6. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589; https://doi.org/10.3390/genes11060589
Available online: https://www.mdpi.com/2073-4425/11/6/589

7. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010; https://doi.org/10.3390/genes11091010
Available online: https://www.mdpi.com/2073-4425/11/9/1010

8. “Transcriptional Factors Regulate Plant Stress Responses Through Mediating Secondary Metabolism”
by Tehseen Ahmad Meraj, Jingye Fu, Muhammad Ali Raza, Chenying Zhu, Qinqin Shen, Dongbei Xu and Qiang Wang
Genes 2020, 11(4), 346; https://doi.org/10.3390/genes11040346
Available online: https://www.mdpi.com/2073-4425/11/4/346

9. “Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response”
by Radhakrishnan Vishnubalaji, Hibah Shaath and Nehad M. Alajez
Genes 2020, 11(7), 760; https://doi.org/10.3390/genes11070760
Available online: https://www.mdpi.com/2073-4425/11/7/760

10. “Regulation of mTORC2 Signaling”
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045; https://doi.org/10.3390/genes11091045
Available online: https://www.mdpi.com/2073-4425/11/9/1045

11. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295; https://doi.org/10.3390/genes11111295
Available online: https://www.mdpi.com/2073-4425/11/11/1295

12. “Down Regulation and Loss of Auxin Response Factor 4 Function Using CRISPR/Cas9 Alters Plant Growth, Stomatal Function and Improves Tomato Tolerance to Salinity and Osmotic Stress”
by Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni et al.
Genes 2020, 11(3), 272; https://doi.org/10.3390/genes11030272
Available online: https://www.mdpi.com/2073-4425/11/3/272

13. “Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts”
by Roman Matyášek and Aleš Kovařík
Genes 2020, 11(7), 761; https://doi.org/10.3390/genes11070761
Available online: https://www.mdpi.com/2073-4425/11/7/761

14. “Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium”
by Jonathan Tak-Sum Chow and Leonardo Salmena
Genes 2020, 11(9), 1002; https://doi.org/10.3390/genes11091002
Available online: https://www.mdpi.com/2073-4425/11/9/1002

15. “A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma”
by Zilong Bian, Rong Fan and Lingmin Xie
Genes 2022, 13(5), 851; https://doi.org/10.3390/genes13050851
Available online: https://www.mdpi.com/2073-4425/13/5/851

16. “Plasmid Transfer by Conjugation in Gram-Negative Bacteria: From the Cellular to the Community Level”
by Chloé Virolle, Kelly Goldlust, Sarah Djermoun, Sarah Bigot and Christian Lesterlin
Genes 2020, 11(11), 1239; https://doi.org/10.3390/genes11111239
Available online: https://www.mdpi.com/2073-4425/11/11/1239

17. “Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors”
by Duran Sürün, Aksana Schneider, Jovan Mircetic, Katrin Neumann, Felix Lansing, Maciej Paszkowski-Rogacz, Vanessa Hänchen, Min Ae Lee-Kirsch and Frank Buchholz
Genes 2020, 11(5), 511; https://doi.org/10.3390/genes11050511
Available online: https://www.mdpi.com/2073-4425/11/5/511

18. “Genetic Modifiers and Rare Mendelian Disease”
by K. M. Tahsin Hassan Rahit and Maja Tarailo-Graovac
Genes 2020, 11(3), 239; https://doi.org/10.3390/genes11030239
Available online: https://www.mdpi.com/2073-4425/11/3/239

19. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120; https://doi.org/10.3390/genes11101120
Available online: https://www.mdpi.com/2073-4425/11/10/1120

20. “The AP2/ERF Gene Family in Triticum durum: Genome-Wide Identification and Expression Analysis under Drought and Salinity Stresses”
by Sahar Faraji, Ertugrul Filiz, Seyed Kamal Kazemitabar, Alessandro Vannozzi, Fabio Palumbo, Gianni Barcaccia and Parviz Heidari
Genes 2020, 11(12), 1464; https://doi.org/10.3390/genes11121464
Available online: https://www.mdpi.com/2073-4425/11/12/1464

We would like to take this opportunity to thank all of the research groups that submitted manuscripts to Genes. We would appreciate it if you could circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest:

Submitting a Manuscript:
Genes is an open access journal that publishes spotlights, reviews, original research contributions, and short communications. Papers may be submitted via the following link:
https://susy.mdpi.com/user/manuscripts/upload/?journal=genes.

Launching a Special Issue:
You have the opportunity to propose hot topics and edit a Special Issue together with experts in the field. More information can be found at the following link:
https://www.mdpi.com/journalproposal/sendproposalspecialissue/genes.

Joining the Editorial Board:
If you are an active researcher in the field of genetics and are interested in joining the Editorial Board, please do not hesitate to get in touch (genes@mdpi.com).

On 9 February 2023, Clarivate, a global leader in providing trusted insights and analytics, added the Preprint Citation Index to the Web of Science platform, streamlining the research process by allowing researchers to locate and link to preprints alongside other trusted content in the database.

The Preprint Citation Index will act as a bridge to connect cutting-edge preprints with peer-reviewed journal articles published within the Web of Science Core Collection. Alerts can be easily set to monitor new research across several repositories and authors will also be able to include preprints on their Web of Science Research Profile to more accurately display their various research outputs.

As of its launch, the Preprint Citation Index will provide nearly two million preprints from various repositories, including MDPI’s own Preprints.org.

MDPI's Preprints Platform – Preprints.org

To advance Open Science and the fast dissemination of research, MDPI offers researchers a free multidisciplinary preprint platform. Preprints.org accepts submissions from all research areas and offers authors high visibility, permanent archiving, article-level Metrics and immediately citable content by assigning a Digital Object Identifier (DOI) to all preprints.

During submission to any MDPI journal, authors have the option to share their research as a preprint. After an initial screening, the manuscript is available online in 48 hours or less. Once online, preprints can be downloaded, shared, commented on, and cited, providing authors maximum visibility.

We invite you to join the ranks of the over 100k researchers using Preprints.org and share your research.

For more information, please visit Preprints.org.

Conference: 11th National Conference on Bioinformatics and Systems Biology
Date: 25–27 February 2023
Place: Guangzhou, China

MDPI will be attending the 11th National Conference on Bioinformatics and Systems Biology (CCBSB2023) as the exhibitor. The National Academic Conference on Bioinformatics and Systems Biology has been successfully held for ten sessions since its first session in 1998. It is a national event with the highest academic level and the greatest influence in the field of bioinformatics research in China. The theme of the conference is "The Latest Frontier Research of Bioinformatics and Systems Biology and Their Applications", and the topics cover translational informatics and data sharing security, biomedical data mining and computing, genome informatics, artificial intelligence and life sciences, group bioinformatics and integrated biology, non-coding RNA and RNA informatics, network biology, major disease omics informatics, biological macromolecular structure prediction and simulation, bioinformatics algorithm research, biological data resources, bioinformatics and drugs discovery, computational synthetic biology, agricultural and forestry informatics and other bioinformatics, and other frontier directions.

The following MDPI journals will be represented:

• Genes;
• JPM;
• Cardiogenetics;
• Bioengineering;
• Biomolecules;
• Metabolites;
• Cells;
• Symmetry;
• Biomedicines;
• Computers;
• COVID;
• Epigenomes.

If you are attending this conference, please feel free to start a conversation with us. Our delegates look forward to meeting you in person and answering any questions that you may have. For more information about the conference, please visit https://ccbsb2022.casconf.cn/.

We are pleased to announce that the 34th meeting of the Developmental Biology Section of the Catalan Society of Biology has set up a free media partnership with Genes (ISSN: 2073-4425). The conference will provide ample opportunities for networking both professionally and socially.

Conference date: 10 Feb 2023
Place: Sala Prat de la Riba, IEC, Spain

This conference brings together the community working in the field of developmental biology. Researchers from different institutions will have the opportunity to spend the day together presenting their results and discussing the latest findings in the field. This meeting is organized by Marta Llimargas (IBMB-CSIC), Barbara Pernaute (CRG), Esteban Hoijman (UB-IDIBELL), Manuel Irimia (CRG) and Marta Morey (UB-IBUB).

For more details, please visit the following link: https://scb.iec.cat/xxxiv-jornada-de-biologia-del-desenvolupament/.

Genes Editorial Office

We are pleased to announce the launch of a new initiative—the MDPI Special Issue Mentor Program.

This program will enable early career researchers (who must hold a Ph.D. in a related field) to experience editing a Special Issue in MDPI journals, under the mentorship of our experienced Editorial Board Members or other experienced scientists. The mentor program will provide an excellent opportunity for early career scientists to gain editorial experience, and to cultivate their ability to edit scientific research.

The mentee’s responsibilities include:

• Proposing a Special Issue title and assisting the mentor in preparing a summary (around 200–400 words) and 3–10 keywords describing the background, importance, and goal of the Issue;
• Writing a brief promotion plan for the Special Issue;
• Preparing a list of scholars who may be interested in the Issue and personally e-mailing invitations on behalf of Guest Editors;
• Writing an editorial for the online Special Issue together with the mentor.

The mentor’s responsibilities include:

• Conducting a final check before the Special Issue is published online;
• Performing editorial control of the Special Issue and quality control of the publications, both of which must be carried out in a timely manner;
• Providing suggestions to younger scholars if they have any doubts or concerns regarding submissions;
• Organizing video calls with young scholars and the Editorial Office regularly to discuss problems and improvement suggestions for the Special Issue;
• Making and submitting decisions regarding submissions with the assistance of mentees.

Certificates and awards:
After the Special Issue closes, the Editorial Office will provide official certificates for all the mentors and early career researchers.

If you are interested in this opportunity, please send your Special Issue proposal to the Editorial Office of a journal you choose, and we will discuss the process (i.e., mentor collaboration, Special Issue topic feasibility analysis, etc.) in further detail. The full list of MDPI journals is as follows: https://www.mdpi.com/about/journals.

In addition to the new Special Issue Mentor Program, we will continue to welcome all Special Issue proposals focusing on hot research topics.

1. “Detection of A-to-I RNA Editing in SARS-COV-2”
by Ernesto Picardi, Luigi Mansi and Graziano Pesole
Genes 2022, 13(1), 41; https://doi.org/10.3390/genes13010041
Full text available online: https://www.mdpi.com/2073-4425/13/1/41

2. “Pyroptosis Patterns Characterized by Distinct Tumor Microenvironment Infiltration Landscapes in Gastric Cancer”
by Renshen Xiang, Yuhang Ge, Wei Song, Jun Ren, Can Kong and Tao Fu
Genes 2021, 12(10), 1535; https://doi.org/10.3390/genes12101535
Full text available online: https://www.mdpi.com/2073-4425/12/10/1535

3. “Machine Learning and Bioinformatics Framework Integration to Potential Familial DCM-Related Markers Discovery”
by Concetta Schiano, Monica Franzese, Filippo Geraci, Mario Zanfardino, Ciro Maiello, Vittorio Palmieri, Andrea Soricelli, Vincenzo Grimaldi, Enrico Coscioni, Marco Salvatore et al.
Genes 2021, 12(12), 1946; https://doi.org/10.3390/genes12121946
Full text available online: https://www.mdpi.com/2073-4425/12/12/1946

4. “PlantMirP2: An Accurate, Fast and Easy-To-Use Program for Plant Pre-miRNA and miRNA Prediction”
by Dashuai Fan, Yuangen Yao and Ming Yi
Genes 2021, 12(8), 1280; https://doi.org/10.3390/genes12081280
Full text available online: https://www.mdpi.com/2073-4425/12/8/1280

5. “Integrated Bioinformatics Analysis Reveals Marker Genes and Potential Therapeutic Targets for Pulmonary Arterial Hypertension”
by Aoqi Li, Jin He, Zhe Zhang, Sibo Jiang, Yun Gao, Yuchun Pan, Huanan Wang and Lenan Zhuang
Genes 2021, 12(9), 1339; https://doi.org/10.3390/genes12091339
Full text available online: https://www.mdpi.com/2073-4425/12/9/1339

6. “Analysis of Codon Usage Patterns of Six Sequenced Brachypodium distachyon Lines Reveals a Declining CG Skew of the CDSs from the 5′-ends to the 3′-ends”
by Jianyong Wang, Yujing Lin and Mengli Xi
Genes 2021, 12(10), 1467; https://doi.org/10.3390/genes12101467
Full text available online: https://www.mdpi.com/2073-4425/12/10/1467

7. “Attention-Based Deep Multiple-Instance Learning for Classifying Circular RNA and Other Long Non-Coding RNA”
by Yunhe Liu, Qiqing Fu, Xueqing Peng, Chaoyu Zhu, Gang Liu and Lei Liu
Genes 2021, 12(12), 2018; https://doi.org/10.3390/genes12122018
Full text available online: https://www.mdpi.com/2073-4425/12/12/2018

8. “Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone”
by George A. Yendewa, Sulaiman Lakoh, Sahr A. Yendewa, Khadijah Bangura, Andrés Tabernilla, Lucia Patiño, Darlinda F. Jiba, Alren O. Vandy, Samuel P. Massaquoi, Nuno S. Osório et al.
Genes 2021, 12(9), 1314; https://doi.org/10.3390/genes12091314
Full text available online: https://www.mdpi.com/2073-4425/12/9/1314

9. “Tandem Mass Tag-Based Quantitative Proteomic Analysis of ISG15 Knockout PK15 Cells in Pseudorabies Virus Infection”
by Wenfeng He, Chen Li, Liangliang Dong, Guoqing Yang and Huimin Liu
Genes 2021, 12(10), 1557; https://doi.org/10.3390/genes12101557
Full text available online: https://www.mdpi.com/2073-4425/12/10/1557

10. “Cell Differentiation Trajectory-Associated Molecular Classification of Osteosarcoma”
by Ankai Xu, Chao Qian, Jinti Lin, Wei Yu, Jiakang Jin, Bing Liu and Huimin Tao
Genes 2021, 12(11), 1685; https://doi.org/10.3390/genes12111685
Full text available online: https://www.mdpi.com/2073-4425/12/11/1685

1. “Single-Step Genomic Evaluations from Theory to Practice: Using SNP Chips and Sequence Data in BLUPF90”
by Daniela Lourenco, Andres Legarra, Shogo Tsuruta, Yutaka Masuda, Ignacio Aguilar and Ignacy Misztal
Genes 2020, 11(7), 790; https://doi.org/10.3390/genes11070790
Available online: https://www.mdpi.com/2073-4425/11/7/790

2. “Turtle Insights into the Evolution of the Reptilian Karyotype and the Genomic Architecture of Sex Determination”
by Basanta Bista and Nicole Valenzuela
Genes 2020, 11(4), 416; https://doi.org/10.3390/genes11040416
Available online: https://www.mdpi.com/2073-4425/11/4/416

3. “Decoding the Role of Satellite DNA in Genome Architecture and Plasticity—An Evolutionary and Clinical Affair”
by Sandra Louzada, Mariana Lopes, Daniela Ferreira, Filomena Adega, Ana Escudeiro, Margarida Gama-Carvalho and Raquel Chaves
Genes 2020, 11(1), 72; https://doi.org/10.3390/genes11010072
Available online: https://www.mdpi.com/2073-4425/11/1/72

4. “Eicosanoid Signaling in Insect Immunology: New Genes and Unresolved Issues”
by Yonggyun Kim and David Stanley
Genes 2021, 12(2), 211; https://doi.org/10.3390/genes12020211
Available online: https://www.mdpi.com/2073-4425/12/2/211

5. “A Gene-Set Enrichment and Protein–Protein Interaction Network-Based GWAS with Regulatory SNPs Identifies Candidate Genes and Pathways Associated with Carcass Traits in Hanwoo Cattle”
by Krishnamoorthy Srikanth, Seung-Hwan Lee, Ki-Yong Chung, Jong-Eun Park, Gul-Won Jang, Mi-Rim Park, Na Yeon Kim, Tae-Hun Kim, Han-Ha Chai, Won Cheoul Park et al.
Genes 2020, 11(3), 316; https://doi.org/10.3390/genes11030316
Available online: https://www.mdpi.com/2073-4425/11/3/316

6. “Microfluidic Quantitative PCR Detection of 12 Transgenes from Horse Plasma for Gene Doping Control”
by Teruaki Tozaki, Aoi Ohnuma, Mio Kikuchi, Taichiro Ishige, Hironaga Kakoi, Kei-ichi Hirota, Kanichi Kusano and Shun-ichi Nagata
Genes 2020, 11(4), 457; https://doi.org/10.3390/genes11040457
Available online: https://www.mdpi.com/2073-4425/11/4/457

7. “Comprehensive Analysis of Differentially Expressed Profiles of mRNA, lncRNA, and circRNA in the Uterus of Seasonal Reproduction Sheep”
by Yongfu La, Xiaoyun He, Liping Zhang, Ran Di, Xiangyu Wang, Shangquan Gan, Xiaosheng Zhang, Jinlong Zhang, Wenping Hu and Mingxing Chu
Genes 2020, 11(3), 301; https://doi.org/10.3390/genes11030301
Available online: https://www.mdpi.com/2073-4425/11/3/301

8. “Comparative Transcriptome Analysis Suggests Key Roles for 5-Hydroxytryptamlne Receptors in Control of Goose Egg Production”
by Qingyuan Ouyang, Shenqiang Hu, Guosong Wang, Jiwei Hu, Jiaman Zhang, Liang Li, Bo Hu, Hua He, Hehe Liu, Lu Xia et al.
Genes 2020, 11(4), 455; https://doi.org/10.3390/genes11040455
Available online: https://www.mdpi.com/2073-4425/11/4/455

9. “Exploring the lncRNAs Related to Skeletal Muscle Fiber Types and Meat Quality Traits in Pigs”
by Rongyang Li, Bojiang Li, Aiwen Jiang, Yan Cao, Liming Hou, Zengkai Zhang, Xiying Zhang, Honglin Liu, Kee-Hong Kim and Wangjun Wu
Genes 2020, 11(8), 883; https://doi.org/10.3390/genes11080883
Available online: https://www.mdpi.com/2073-4425/11/8/883

10. “Genomic Identification, Evolution and Sequence Analysis of the Heat-Shock Protein Gene Family in Buffalo”
by Saif ur Rehman, Asif Nadeem, Maryam Javed, Faiz-ul Hassan, Xier Luo, Ruqayya Bint Khalid
and Qingyou Liu
Genes 2020, 11(11), 1388; https://doi.org/10.3390/genes11111388
Available online: https://www.mdpi.com/2073-4425/11/11/1388 

1. “Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis”
by Massimo Venditti, Mariem Ben Rhouma, Maria Zelinda Romano, Imed Messaoudi, Russel J. Reiter and Sergio Minucci
Genes 2021, 12(7), 1016; https://doi.org/10.3390/genes12071016
Full text available online: https://www.mdpi.com/2073-4425/12/7/1016

2. “Genetics and Epigenetics in Allergic Rhinitis”
by Choi, Bo Yoon, Munsoo Han, Ji Won Kwak and Tae Hoon Kim
Genes 2021, 12(12), 2004; https://doi.org/10.3390/genes12122004
Full text available online: https://www.mdpi.com/2073-4425/12/12/2004

3. “LINCking the Nuclear Envelope to Sperm Architecture”
by Francesco Manfrevola, Florian Guillou, Silvia Fasano, Riccardo Pierantoni and Rosanna Chianese
Genes 2021, 12(5), 658; https://doi.org/10.3390/genes12050658
Full text available online: https://www.mdpi.com/2073-4425/12/5/658

4. “Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints”
by Jiaqi Wu, Takahiro Yonezawa and Hirohisa Kishino
Genes 2021, 12(5), 740; https://doi.org/10.3390/genes12050740
Full text available online: https://www.mdpi.com/2073-4425/12/5/740

5. “Pediatric and Adolescent Oncofertility in Male Patients—From Alpha to Omega”
by Ovidiu Bîcă, Ioan Sârbu and Carmen Iulia Ciongradi
Genes 2021, 12(5), 701; https://doi.org/10.3390/genes12050701
Full text available online: https://www.mdpi.com/2073-4425/12/5/701

6. “Methylation of Host Genes Associated with Coronavirus Infection from Birth to 26 Years”
by Rutu Rathod, Aniruddha Rathod, Parnian Kheirkhah Rahimabad, Jiasong Duan, Hongmei Zhang, S. Hasan Arshad and Wilfried Karmaus
Genes 2021, 12(8), 1198; https://doi.org/10.3390/genes12081198
Full text available online: https://www.mdpi.com/2073-4425/12/8/1198

7. “Prospects in Connecting Genetic Variation to Variation in Fertility in Male Bees”
by Garett P. Slater, Nicholas M. A. Smith and Brock A. Harpur
Genes 2021, 12(8), 1251; https://doi.org/10.3390/genes12081251
Full text available online: https://www.mdpi.com/2073-4425/12/8/1251

8. “Identification of Long Non-Coding RNAs Involved in Porcine Fat Deposition Using Two High-Throughput Sequencing Methods”
by Yibing Liu, Ying Yu, Hong Ao, Fengxia Zhang, Xitong Zhao, Huatao Liu, Yong Shi, Kai Xing and Chuduan Wang
Genes 2021, 12(9), 1374; https://doi.org/10.3390/genes12091374
Full text available online: https://www.mdpi.com/2073-4425/12/9/1374

9. “Epigenetic Regulation of CDH1 Is Altered after HOXB7-Silencing in MDA-MB-468 Triple-Negative Breast Cancer Cells”
by Ana Paço, Joana Leitão-Castro and Renata Freitas
Genes 2021, 12(10), 1575; https://doi.org/10.3390/genes12101575
Full text available online: https://www.mdpi.com/2073-4425/12/10/1575

10. “Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition”
by Yan Li, Carol A. Pollock and Sonia Saad
Genes 2021, 12(11), 1653; https://doi.org/10.3390/genes12111653
Full text available online: https://www.mdpi.com/2073-4425/12/11/1653

1. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589; https://doi.org/10.3390/genes11060589
Full text available online: https://www.mdpi.com/2073-4425/11/6/589

2. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010; https://doi.org/10.3390/genes11091010
Full text available online: https://www.mdpi.com/2073-4425/11/9/1010

3. “Regulation of mTORC2 Signaling”     
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045; https://doi.org/10.3390/genes11091045
Full text available online: https://www.mdpi.com/2073-4425/11/9/1045

4. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295; https://doi.org/10.3390/genes11111295
Full text available online: https://www.mdpi.com/2073-4425/11/11/1295

5. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120; https://doi.org/10.3390/genes11101120
Full text available online: https://www.mdpi.com/2073-4425/11/10/1120

6. “Therapeutic Strategies for Duchenne Muscular Dystrophy: An Update”
by Chengmei Sun, Luoan Shen, Zheng Zhang and Xin Xie
Genes 2020, 11(8), 837; https://doi.org/10.3390/genes11080837
Full text available online: https://www.mdpi.com/2073-4425/11/8/837

7. “RET Gene Fusions in Malignancies of the Thyroid and Other Tissues”
by Massimo Santoro, Marialuisa Moccia, Giorgia Federico and Francesca Carlomagno
Genes 2020, 11(4), 424; https://doi.org/10.3390/genes11040424
Full text available online: https://www.mdpi.com/2073-4425/11/4/424

8. “The Microbiome in Cystic Fibrosis Pulmonary Disease”
by Alice Françoise and Geneviève Héry-Arnaud
Genes 2020, 11(5), 536; https://doi.org/10.3390/genes11050536
Full text available online: https://www.mdpi.com/2073-4425/11/5/536 

9. “Extracellular Vesicles Derived from Human Gingival Mesenchymal Stem Cells: A Transcriptomic Analysis”
by Serena Silvestro, Luigi Chiricosta, Agnese Gugliandolo, Jacopo Pizzicannella, Francesca Diomede, Placido Bramanti, Oriana Trubiani and Emanuela Mazzon
Genes 2020, 11(2), 118; https://doi.org/10.3390/genes11020118
Full text available online: https://www.mdpi.com/2073-4425/11/2/118

10. “The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions”
by Rameez Hassan Pirzada, Nasir Javaid and Sangdun Choi
Genes 2020, 11(2), 131; https://doi.org/10.3390/genes11020131
Full text available online: https://www.mdpi.com/2073-4425/11/2/131

MDPI has just become the first open access (OA) publisher to reach the milestone of one million articles published. That is one million articles freely available to all, to circulate and build upon! We are proud to share this special moment with the global scientific community.

This landmark has been reached thanks to the immeasurable support of more than 600,000 expert reviewers, 66,000 editorial board members and 6700 hard-working colleagues across MDPI’s global offices.

Within more than 25 years of publishing, our journals received 2.1 million manuscripts and generated 4.6 million peer review reports to get to one million papers published.

Reaching the milestone of one million articles published reinforces our mission to remove any existing barriers and to make scientific research accessible to all. Since its inception, MDPI’s goal has been to create reliable processes to make science open. This is a path towards facilitating the dissemination of novel insights in scientific communities.

Regular feedback from authors and reviewers shows that our service is greatly appreciated and needed. At the same time, the feedback helps us identify areas for further improvement.

As it stands, a significant share of published research findings remain closed access. More than half of the content published with the most well-known legacy publishers stays behind a paywall, and that is not including articles published in hybrid OA journals, or made available months or years after publication.

A new policy announced by the US administration in August 2022 requires that, as of January 2026, all US federally funded research be made freely and immediately available after publication. While the new policy does not mandate articles be published under an open access license, it is aligned with the open access movement in removing all barriers to research. Similarly, some of the most advanced research institutions in the world intend to have all funded research articles published in open access by 2025.

MDPI is proud to be the leading agent of the transition to open access.

"Thanks a Million" to all the contributors!

1. “Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas”
by Jorge Lalucat, Magdalena Mulet, Margarita Gomila and Elena García-Valdés
Genes 2020, 11(2), 139; https://doi.org/10.3390/genes11020139
Full text available online: https://www.mdpi.com/2073-4425/11/2/139

2. “Plasmid Transfer by Conjugation in Gram-Negative Bacteria: From the Cellular to the Community Level”
by Chloé Virolle, Kelly Goldlust, Sarah Djermoun, Sarah Bigot and Christian Lesterlin
Genes 2020, 11(11), 1239; https://doi.org/10.3390/genes11111239
Full text available online: https://www.mdpi.com/2073-4425/11/11/1239 

3. “Farnesol and Tyrosol: Secondary Metabolites with a Crucial quorum-sensing Role in Candida Biofilm Development”
by Célia F. Rodrigues and Lucia Černáková
Genes 2020, 11(4), 444; https://doi.org/10.3390/genes11040444  
Full text available online: https://www.mdpi.com/2073-4425/11/4/444

4. “Butyrate Levels in the Transition from an Infant- to an Adult-Like Gut Microbiota Correlate with Bacterial Networks Associated with Eubacterium Rectale and Ruminococcus Gnavus”
by Morten Nilsen, Carina Madelen Saunders, Inga Leena Angell, Magnus Ø. Arntzen, Karin C. Lødrup Carlsen, Kai-Håkon Carlsen, Guttorm Haugen, Live Heldal Hagen, Monica H. Carlsen, Gunilla Hedlin et al.
Genes 2020, 11(11), 1245; https://doi.org/10.3390/genes11111245  
Full text available online: https://www.mdpi.com/2073-4425/11/11/1245

5. “Genes, Pathways, and Mechanisms Involved in the Virulence of Mucorales”
by Carlos Lax, Carlos Pérez-Arques, María Isabel Navarro-Mendoza, José Tomás Cánovas-Márquez, Ghizlane Tahiri, José Antonio Pérez-Ruiz, Macario Osorio-Concepción, Laura Murcia-Flores, Eusebio Navarro, Victoriano Garre et al.
Genes 2020, 11(3), 317; https://doi.org/10.3390/genes11030317  
Full text available online: https://www.mdpi.com/2073-4425/11/3/317

6. “Comparison of Illumina versus Nanopore 16S rRNA Gene Sequencing of the Human Nasal Microbiota”
by Astrid P. Heikema, Deborah Horst-Kreft, Stefan A. Boers, Rick Jansen, Saskia D. Hiltemann, Willem de Koning, Robert Kraaij, Maria A. J. de Ridder, Chantal B. van Houten, Louis J. Bont et al.
Genes 2020, 11(9), 1105; https://doi.org/10.3390/genes11091105  
Full text available online: https://www.mdpi.com/2073-4425/11/9/1105

7. “Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery”
by Arijit Bhattacharya, Audrey Corbeil, Rubens L. do Monte-Neto and Christopher Fernandez-Prada
Genes 2020, 11(7), 722; https://doi.org/10.3390/genes11070722  
Full text available online: https://www.mdpi.com/2073-4425/11/7/722

8. “Comparative Genomic Analysis of Lactiplantibacillus plantarum Isolated from Different Niches”
by Bingyong Mao, Ruimin Yin, Xiaoshu Li, Shumao Cui, Hao Zhang, Jianxin Zhao and Wei Chen
Genes 2021, 12(2), 241; https://doi.org/10.3390/genes12020241  
Full text available online: https://www.mdpi.com/2073-4425/12/2/241 

9. “Comparative Genomics Analysis of Lactobacillus ruminis from Different Niches”
by Shuo Wang, Bo Yang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang and Wei Chen
Genes 2020, 11(1), 70; https://doi.org/10.3390/genes11010070  
Full text available online: https://www.mdpi.com/2073-4425/11/1/70

10. “Hybridization Facilitates Adaptive Evolution in Two Major Fungal Pathogens”
by Himeshi Samarasinghe, Man You, Thomas S. Jenkinson, Jianping Xu and Timothy Y. James
Genes 2020, 11(1), 101; https://doi.org/10.3390/genes11010101  
Full text available online: https://www.mdpi.com/2073-4425/11/1/101

1. “Genetic Modifiers and Rare Mendelian Disease”
by K. M. Tahsin Hassan Rahit and Maja Tarailo-Graovac
Genes 2020, 11(3), 239; https://doi.org/10.3390/genes11030239
Full text available online: https://www.mdpi.com/2073-4425/11/3/239

2. “Rapid Direct Nucleic Acid Amplification Test without RNA Extraction for SARS-CoV-2 Using a Portable PCR Thermocycler”
by Soon Keong Wee, Suppiah Paramalingam Sivalingam and Eric Peng Huat Yap
Genes 2020, 11(6), 664; https://doi.org/10.3390/genes11060664
Full text available online: https://www.mdpi.com/2073-4425/11/6/664 

3. “Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract”
by Jaewon J. Lee, Scott Kopetz, Eduardo Vilar, John Paul Shen, Ken Chen and Anirban Maitra
Genes 2020, 11(6), 645; https://doi.org/10.3390/genes11060645
Full text available online: https://www.mdpi.com/2073-4425/11/6/645

4. “Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic”
by Sureshnee Pillay, Jennifer Giandhari, Houriiyah Tegally, Eduan Wilkinson, Benjamin Chimukangara, Richard Lessells, Yunus Moosa, Stacey Mattison, Inbal Gazy, Maryam Fish et al.
Genes 2020, 11(8), 949; https://doi.org/10.3390/genes11080949
Full text available online: https://www.mdpi.com/2073-4425/11/8/949

5. “mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell Biomarkers”
by Yitong Zhang, Joseph Ta-Chien Tseng, I-Chia Lien, Fenglan Li, Wei Wu and Hui Li
Genes 2020, 11(3), 257; https://doi.org/10.3390/genes11030257
Full text available online: https://www.mdpi.com/2073-4425/11/3/257

6. “Standards for Methods Utilizing Environmental DNA for Detection of Fish Species”
by Lu Shu, Arne Ludwig and Zuogang Peng
Genes 2020, 11(3), 296; https://doi.org/10.3390/genes11030296
Full text available online: https://www.mdpi.com/2073-4425/11/3/296

7. “Analytical Sensitivity and Specificity of Two RT-qPCR Protocols for SARS-CoV-2 Detection Performed in an Automated Workflow”
by Gustavo Barcelos Barra, Ticiane Henriques Santa Rita, Pedro Góes Mesquita, Rafael Henriques Jácomo and Lídia Freire Abdalla Nery
Genes 2020, 11(10), 1183; https://doi.org/10.3390/genes11101183
Full text available online: https://www.mdpi.com/2073-4425/11/10/1183

8. “Delivery Approaches for Therapeutic Genome Editing and Challenges”
by Ilayda Ates, Tanner Rathbone, Callie Stuart, P. Hudson Bridges and Renee N. Cottle
Genes 2020, 11(10), 1113; https://doi.org/10.3390/genes11101113
Full text available online: https://www.mdpi.com/2073-4425/11/10/1113

9. “An Improved Phenotype-Driven Tool for Rare Mendelian Variant Prioritization: Benchmarking Exomiser on Real Patient Whole-Exome Data”
by Valentina Cipriani, Nikolas Pontikos, Gavin Arno, Panagiotis I. Sergouniotis, Eva Lenassi, Penpitcha Thawong, Daniel Danis, Michel Michaelides, Andrew R. Webster, Anthony T. Moore et al.
Genes 2020, 11(4), 460; https://doi.org/10.3390/genes11040460
Full text available online: https://www.mdpi.com/2073-4425/11/4/460

10. “DNA6mA-MINT: DNA-6mA Modification Identification Neural Tool”
by Mobeen Ur Rehman and Kil To Chong
Genes 2020, 11(8), 898; https://doi.org/10.3390/genes11080898
Full text available online: https://www.mdpi.com/2073-4425/11/8/898

1. “Subcellular Localization of miRNAs and Implications in Cellular Homeostasis”
by Minwen Jie, Tong Feng, Wei Huang, Moran Zhang, Yuliang Feng, Hao Jiang and Zhili Wen
Genes 2021, 12(13), 856; https://doi.org/10.3390/genes12060856
Full text available online: https://www.mdpi.com/2073-4425/12/6/856

2. “Ribosomal RNA Transcription Regulation in Breast Cancer”
by Cecelia M. Harold, Amber F. Buhagiar, Yan Cheng and Susan J. Baserga
Genes 2021, 12(4), 502; https://doi.org/10.3390/genes12040502
Full text available online: https://www.mdpi.com/2073-4425/12/4/502

3. “Hsa-miR-375/RASD1 Signaling May Predict Local Control in Early Breast Cancer”
by Barbara Zellinger, Ulrich Bodenhofer, Immanuela A. Engländer, Cornelia Kronberger, Peter Strasser, Brane Grambozov, Gerd Fastner, Markus Stana, Roland Reitsamer Karl Sotlar et al.
Genes 2020, 11(2), 1404; https://doi.org/10.3390/genes11121404
Full text available online: https://www.mdpi.com/2073-4425/11/12/1404

4. “Essential Role of the 14q32 Encoded miRNAs in Endocrine Tumors”
by Lilla Krokker, Attila Patócs and Henriett Butz
Genes 2021, 12(5), 698; https://doi.org/10.3390/genes12050698
Full text available online: https://www.mdpi.com/2073-4425/12/5/698

5. “The Ribosomal Gene Loci—The Power behind the Throne”
by Konstantin I. Panov, Katherine Hannan, Ross D. Hannan and Nadine Hein
Genes 2021, 12(5), 763; https://doi.org/10.3390/genes12050763
Full text available online: https://www.mdpi.com/2073-4425/12/5/763

6. “Spt4 Promotes Pol I Processivity and Transcription Elongation”
by Abigail K. Huffines, Yvonne J. K. Edwards and David A. Schneider
Genes 2021, 12(3), 413; https://doi.org/10.3390/genes12030413
Full text available online: https://www.mdpi.com/2073-4425/12/3/413

7. “Harnessing the Nucleolar DNA Damage Response in Cancer Therapy”
by Jiachen Xuan, Kezia Gitareja, Natalie Brajanovski and Elaine Sanij
Genes 2021, 12(8), 1156; https://doi.org/10.3390/genes12081156
Full text available online: https://www.mdpi.com/2073-4425/12/8/1156

8. “Pincho: A Modular Approach to High Quality De Novo Transcriptomics”
by Randy Ortiz, Priyanka Gera, Christopher Rivera and Juan C. Santos
Genes 2021, 12(7), 953; https://doi.org/10.3390/genes12070953
Full text available online: https://www.mdpi.com/2073-4425/12/7/953

9. “DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription”
by William J. Andrews, Swagat Ray, Tatiana Panova, Christoph Engel and Konstantin I. Panov
Genes 2021, 12(9), 1412; https://doi.org/10.3390/genes12091412
Full text available online: https://www.mdpi.com/2073-4425/12/9/1412

10. “Computational Identification of Sex-Biased Biomarker MicroRNAs and Genes Associated with Immune Infiltration in Breast Cancer”
by Eric W. Li and Yongsheng Bai
Genes 2021, 12(4), 570; https://doi.org/10.3390/genes12040570
Full text available online: https://www.mdpi.com/2073-4425/12/4/570

1. “Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability”
by Giorgio Milazzo, Daniele Mercatelli, Giulia Di Muzio, Luca Triboli, Piergiuseppe De Rosa, Giovanni Perini and Federico M. Giorgi
Genes 2020, 11(5), 556; https://doi.org/10.3390/genes11050556
Full text available online: https://www.mdpi.com/2073-4425/11/5/556

2. “Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts”
by Roman Matyášek and Aleš Kovařík
Genes 2020, 11(7), 761; https://doi.org/10.3390/genes11070761
Full text available online: https://www.mdpi.com/2073-4425/11/7/761

3. “Trans-Atlantic Distribution and Introgression as Inferred from Single Nucleotide Polymorphism: Mussels Mytilus and Environmental Factors”
by Roman Wenne, Małgorzata Zbawicka, Lis Bach, Petr Strelkov, Mikhail Gantsevich, Piotr Kukliński, Tomasz Kijewski, John H. McDonald, Kristil Kindem Sundsaasen, Mariann Árnyasi et al.
Genes 2020, 11(5), 530; https://doi.org/10.3390/genes11050530
Full text available online: https://www.mdpi.com/2073-4425/11/5/530

4. “The Biochemistry of Cytoplasmic Incompatibility Caused by Endosymbiotic Bacteria”
by Hongli Chen, Mengwen Zhang and Mark Hochstrasser
Genes 2020, 11(8), 852; https://doi.org/10.3390/genes11080852
Full text available online: https://www.mdpi.com/2073-4425/11/8/852

5. “The Female-Specific W Chromosomes of Birds Have Conserved Gene Contents but Are Not Feminized”
by Luohao Xu and Qi Zhou
Genes 2020, 11(10), 1126; https://doi.org/10.3390/genes11101126
Full text available online: https://www.mdpi.com/2073-4425/11/10/1126

6. “Climate Change and Green Sea Turtle Sex Ratio—Preventing Possible Extinction”
by Jana Blechschmidt, Meike J. Wittmann and Chantal Blüml
Genes 2020, 11(5), 588; https://doi.org/10.3390/genes11050588
Full text available online: https://www.mdpi.com/2073-4425/11/5/588

7. “How Depressing Is Inbreeding? A Meta-Analysis of 30 Years of Research on the Effects of Inbreeding in Livestock”
by Harmen P. Doekes, Piter Bijma and Jack J. Windig
Genes 2021, 12(6), 926; https://doi.org/10.3390/genes12060926
Full text available online: https://www.mdpi.com/2073-4425/12/6/926

8. “Genomic Diversity, Population Structure, and Signature of Selection in Five Chinese Native Sheep Breeds Adapted to Extreme Environments”
by Adam Abied, Alnoor Bagadi, Farhad Bordbar, Yabin Pu, Serafino M. A. Augustino, Xianglan Xue, Feng Xing, Gebremedhin Gebreselassie, Jian-Lin Han, Joram M. Mwacharo et al.
Genes 2020, 11(5), 494; https://doi.org/10.3390/genes11050494
Full text available online: https://www.mdpi.com/2073-4425/11/5/494

9. “Interstitial Telomeric Repeats Are Rare in Turtles”
by Lorenzo Clemente, Sofia Mazzoleni, Eleonora Pensabene Bellavia, Barbora Augstenová, Markus Auer, Peter Praschag, Tomáš Protiva, Petr Velenský, Philipp Wagner, Uwe Fritz et al.
Genes 2020, 11(6), 657; https://doi.org/10.3390/genes11060657
Full text available online: https://www.mdpi.com/2073-4425/11/6/657

10. “Highly Rearranged Karyotypes and Multiple Sex Chromosome Systems in Armored Catfishes from the Genus Harttia (Teleostei, Siluriformes)”
by Geize Aparecida Deon, Larissa Glugoski, Marcelo Ricardo Vicari, Viviane Nogaroto, Francisco de Menezes Cavalcante Sassi, Marcelo de Bello Cioffi, Thomas Liehr, Luiz Antonio Carlos Bertollo and Orlando Moreira-Filho
Genes 2020, 11(11), 1366; https://doi.org/10.3390/genes11111366
Full text available online: https://www.mdpi.com/2073-4425/11/11/1366

1. “Transcriptional Factors Regulate Plant Stress Responses Through Mediating Secondary Metabolism”
by Tehseen Ahmad Meraj, Jingye Fu, Muhammad Ali Raza, Chenying Zhu, Qinqin Shen, Dongbei Xu and Qiang Wang
Genes 2020, 11(4), 346; https://doi.org/10.3390/genes11040346
Available online: https://doi.org/10.3390/genes11040346

2. “Down Regulation and Loss of Auxin Response Factor 4 Function Using CRISPR/Cas9 Alters Plant Growth, Stomatal Function and Improves Tomato Tolerance to Salinity and Osmotic Stress”
by Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni et al.
Genes 2020, 11(3), 272; https://doi.org/10.3390/genes11030272
Available online: https://doi.org/10.3390/genes11030272

3. “The AP2/ERF Gene Family in Triticum durum: Genome-Wide Identification and Expression Analysis under Drought and Salinity Stresses”
by Sahar Faraji, Ertugrul Filiz, Seyed Kamal Kazemitabar, Alessandro Vannozzi, Fabio Palumbo, Gianni Barcaccia and Parviz Heidari
Genes 2020, 11(12), 1464; https://doi.org/10.3390/genes11121464
Available online: https://doi.org/10.3390/genes11121464

4. “Controlling Apomixis: Shared Features and Distinct Characteristics of Gene Regulation”
by Anja Schmidt
Genes 2020, 11(3), 329; https://doi.org/10.3390/genes11030329
Available online: https://doi.org/10.3390/genes11030329

5. “Harnessing Crop Wild Diversity for Climate Change Adaptation”
by Andrés J. Cortés and Felipe López-Hernández
Genes 2021, 12(5), 783; https://doi.org/10.3390/genes12050783
Available online: https://doi.org/10.3390/genes12050783

6. “Genome-Wide Analysis of Potassium Channel Genes in Rice: Expression of the OsAKT and OsKAT Genes under Salt Stress”
by Zahra Musavizadeh, Hamid Najafi-Zarrini, Seyed Kamal Kazemitabar, Seyed Hamidreza Hashemi, Sahar Faraji, Gianni Barcaccia and Parviz Heidari
Genes 2021, 12(5), 784; https://doi.org/10.3390/genes12050784
Available online: https://doi.org/10.3390/genes12050784

7. “Low Temperature Promotes Anthocyanin Biosynthesis and Related Gene Expression in the Seedlings of Purple Head Chinese Cabbage (Brassica rapa L.)”
by Qiong He, Yanjing Ren, Wenbin Zhao, Ru Li and Lugang Zhang
Genes 2020, 11(1), 81; https://doi.org/10.3390/genes11010081
Available online: https://doi.org/10.3390/genes11010081

8. “Plants’ Epigenetic Mechanisms and Abiotic Stress”
by Matin Miryeganeh
Genes 2021, 12(8), 1106; https://doi.org/10.3390/genes12081106
Available online: https://doi.org/10.3390/genes12081106

9. “HD-ZIP Gene Family: Potential Roles in Improving Plant Growth and Regulating Stress-Responsive Mechanisms in Plants”
by Rahat Sharif, Ali Raza, Peng Chen, Yuhong Li, Enas M. El-Ballat, Abdur Rauf, Christophe Hano and Mohamed A. El-Esawi
Genes 2021, 12(8), 1256; https://doi.org/10.3390/genes12081256
Available online: https://doi.org/10.3390/genes12081256

10. “The Critical Role of miRNAs in Regulation of Flowering Time and Flower Development”
by Saquib Waheed and Lihui Zeng
Genes 2020, 11(3), 319; https://doi.org/10.3390/genes11030319
Available online: https://doi.org/10.3390/genes11030319

We are pleased to announce that the website of the MDPI Sustainability Foundation has been revamped! For the past couple of months, our UX UI team and front-end developers have been working hard to launch the website in time for the opening of the Sustainability Awards nominations.

The website is not the only thing that has had a remodeling. Indeed, the format of the Emerging Sustainability Leader Award (ESLA) has been updated. ESLA is now a competition open to individual researchers or start-ups founded by researchers under the age of 35. Nominee applications will go through 2 rounds of selection until the final 3 are decided. The finalists will then be invited to give pitch presentations during the Award Ceremony to win either first place (10,000 USD) or runner-up (2 x 5000 USD).

The World Sustainability Award, on the other hand, remains the same: a total prize money of 100,000 USD is up for grabs by senior individual researchers or groups of researchers from the international research community.

Nominations for both the World Sustainability Award and the Emerging Sustainability Leader award are now open! Check out our new website for more information on how to nominate.

1. “Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy”
by Jac A. Nickoloff, Neelam Sharma and Lynn Taylor
Genes 2020, 11(1), 99; https://doi.org/10.3390/genes11010099
Full text available online: https://www.mdpi.com/2073-4425/11/1/99

2. “Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response”
by Radhakrishnan Vishnubalaji, Hibah Shaath and Nehad M. Alajez
Genes 2020, 11(7), 760; https://doi.org/10.3390/genes11070760
Full text available online: https://www.mdpi.com/2073-4425/11/7/760

3. “Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium”
by Jonathan Tak-Sum Chow and Leonardo Salmena
Genes 2020, 11(9), 1002; https://doi.org/10.3390/genes11091002
Full text available online: https://www.mdpi.com/2073-4425/11/9/1002

4. “Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response”
by Sandrine Ragu, Gabriel Matos-Rodrigues and Bernard S. Lopez
Genes 2020, 11(4), 409; https://doi.org/10.3390/genes11040409
Full text available online: https://www.mdpi.com/2073-4425/11/4/409

5. “Circulatory miR-133b and miR-21 as Novel Biomarkers in Early Prediction and Diagnosis of Coronary Artery Disease”
by Dinesh Kumar, Rajiv Narang, Vishnubhatla Sreenivas, Vandana Rastogi, Jagriti Bhatia, Daman Saluja and Kamna Srivastava
Genes 2020, 11(2), 164; https://doi.org/10.3390/genes11020164
Full text available online: https://www.mdpi.com/2073-4425/11/2/164

6. “DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons”
by Therese Wilhelm, Maha Said and Valeria Naim
Genes 2020, 11(6), 642; https://doi.org/10.3390/genes11060642
Full text available online: https://www.mdpi.com/2073-4425/11/6/642

7. “HMGA2 as a Critical Regulator in Cancer Development”
by Behzad Mansoori, Ali Mohammadi, Henrik J. Ditzel, Pascal H. G. Duijf, Vahid Khaze, Morten F. Gjerstorff and Behzad Baradaran
Genes 2021, 12(2), 269; https://doi.org/10.3390/genes12020269
Full text available online: https://www.mdpi.com/2073-4425/12/2/269

8. “Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs”
by Swayam Prakash Srivastava, Julie E. Goodwin, Keizo Kanasaki and Daisuke Koya
Genes 2020, 11(2), 211; https://doi.org/10.3390/genes11020211
Full text available online: https://www.mdpi.com/2073-4425/11/2/211

9. “Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update”
by Yuri Motorin and Virginie Marchand
Genes 2021, 12(2), 278; https://doi.org/10.3390/genes12020278
Full text available online: https://www.mdpi.com/2073-4425/12/2/278

10. “History of DNA Helicases”
by Robert M. Brosh, Jr. and Steven W. Matson
Genes 2020, 11(3), 255; https://doi.org/10.3390/genes11030255
Full text available online: https://www.mdpi.com/2073-4425/11/3/255

On behalf of the Organizing Committee of the International Conference Single-Cell Genomics Moving Forward, we are pleased to announce the preliminary list of keynote and invited talks, that will be hosted by the following speakers.

Feature Speakers:

• Prof. Oliver Stegle (DKFZ, Germany);
• Prof. Sandrine Dudoit (University of California, USA).

Invited Speakers:

• Dr. Antonio Herrera Camacho (EPFL, Switzerland);
• Dr. Krasimira Tsaneva-Atanasova (University of Exeter, UK);
• Dr. Nacho Molina (IGBMC, France);
• Dr. Irene Papatheodorou (EMBL-EBI, UK);
• Dr. Merav Cohen (Tel Aviv University, Israel);
• Dr. Anelia Horvath (George Washington University, USA);
• Dr. Björn Reinius (Karolinska Institutet, Sweden);
• Dr. Merja Heinäniemi (University of Eastern Finland, Finland).

Furthermore, the program will include workshops and collaborative discussion sessions on recent outstanding achievements made in single-cell research. It will focus on identifying future trends and the needs of the field and on proposing and discussing innovative interdisciplinary approaches to address them.

We look forward to meeting you and discussing your exciting single-cell research in Barcelona from 29 to 31 March 2023!

1. “Harnessing Crop Wild Diversity for Climate Change Adaptation”
by Andrés J. Cortés and Felipe López-Hernández
Genes 2021, 12(5), 783; https://doi.org/10.3390/genes12050783
Available online: https://www.mdpi.com/2073-4425/12/5/783

2. “Genome-Wide Analysis of Potassium Channel Genes in Rice: Expression of the OsAKT and OsKAT Genes under Salt Stress”
by Zahra Musavizadeh, Hamid Najafi-Zarrini, Seyed Kamal Kazemitabar, Seyed Hamidreza Hashemi, Sahar Faraji, Gianni Barcaccia and Parviz Heidari
Genes 2021, 12(5), 784; https://doi.org/10.3390/genes12050784
Available online: https://doi.org/10.3390/genes12050784

3. “Plants’ Epigenetic Mechanisms and Abiotic Stress”
by Matin Miryeganeh
Genes 2021, 12(8), 1106; https://doi.org/10.3390/genes12081106
Available online: https://doi.org/10.3390/genes12081106 

4. “HD-ZIP Gene Family: Potential Roles in Improving Plant Growth and Regulating Stress-Responsive Mechanisms in Plants”
by Rahat Sharif, Ali Raza, Peng Chen, Yuhong Li, Enas M. El-Ballat, Abdur Rauf, Christophe Hano and Mohamed A. El-Esawi
Genes 2021, 12(8), 1256; https://doi.org/10.3390/genes12081256
Available online: https://doi.org/10.3390/genes12081256

5. “Allelic Diversity at Abiotic Stress Responsive Genes in Relationship to Ecological Drought Indices for Cultivated Tepary Bean, Phaseolus acutifolius A. Gray, and Its Wild Relatives”
by María A. Buitrago-Bitar, Andrés J. Cortés, Felipe López-Hernández, Jorge M. Londoño-Caicedo, Jaime E. Muñoz-Florez, L. Carmenza Muñoz and Matthew Wohlgemuth Blair
Genes 2021, 12(4), 556; https://doi.org/10.3390/genes12040556
Available online: https://doi.org/10.3390/genes12040556

6. “The Genetic Basis of Tomato Aroma”
by Matteo Martina, Yury Tikunov, Ezio Portis and Arnaud G. Bovy
Genes 2021, 12(2), 226; https://doi.org/10.3390/genes12020226
Available online: https://doi.org/10.3390/genes12020226

7. “Role of Basal ABA in Plant Growth and Development”
by Benjamin P. Brookbank, Jasmin Patel, Sonia Gazzarrini and Eiji Nambara
Genes 2021, 12(12), 1936; https://doi.org/10.3390/genes12121936
Available online: https://doi.org/10.3390/genes12121936

8. “Circadian Clock Components Offer Targets for Crop Domestication and Improvement”
by C. Robertson McClung
Genes 2021, 12(3), 374; https://doi.org/10.3390/genes12030374
Available online: https://doi.org/10.3390/genes12030374

9. “The Development of Herbicide Resistance Crop Plants Using CRISPR/Cas9-Mediated Gene Editing”
by Huirong Dong, Yong Huang and Kejian Wang
Genes 2021, 12(6), 912; https://doi.org/10.3390/genes12060912
Available online: https://doi.org/10.3390/genes12060912

10. “Regulation of Vitamin C Accumulation for Improved Tomato Fruit Quality and Alleviation of Abiotic Stress”
by Ifigeneia Mellidou, Athanasios Koukounaras, Stefanos Kostas, Efstathia Patelou and Angelos K. Kanellis
Genes 2021, 12(5), 694; https://doi.org/10.3390/genes12050694
Available online: https://doi.org/10.3390/genes12050694

We are pleased to share that 197 Editorial Board Members and Guest Editors from MDPI’s journal Genes (ISSN: 2073-4425) were featured in Stanford’s List of the World's Top 2% Scientists.

The list was created by Prof. John P. A. Ioannidis from Stanford University and his research team. They have created a publicly available database of 100,000 top-cited scientists that provides standardized information on citations, h-index, co-authorship adjusted hm-index, citations to papers in different authorship positions and a composite indicator (c-score). Scientists are classified into 22 scientific fields and 176 sub-fields.

We would like to congratulate our Editorial Board Members and Guest Editors on their excellent achievement and thank them for their immense contribution to the scientific progression and development of Genes.

1. “HMGA2 as a Critical Regulator in Cancer Development”
by Mansoori, B., Mohammadi, A., Ditzel, H. J., Duijf, P. H. G., Khaze, V., Gjerstorff, M. F. and Baradaran, B.
Genes 2021, 12(2), 269; https://doi.org/10.3390/genes12020269
Full text available online: https://www.mdpi.com/2073-4425/12/2/269

2. “Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring”
by Martins, I., Ribeiro, I. P., Jorge, J., Gonçalves, A. C., Sarmento-Ribeiro, A. B., Melo, J. B. and Carreira, I. M.
Genes 2021, 12(3), 349; https://doi.org/10.3390/genes12030349
Full text available online: https://www.mdpi.com/2073-4425/12/3/349

3. “Decipher the Glioblastoma Microenvironment: The First Milestone for New Groundbreaking Therapeutic Strategies”
by Fanelli, G. N., Grassini, D., Ortenzi, V., Pasqualetti, F., Montemurro, N., Perrini, P., Naccarato, A. G. and Scatena, C.
Genes 2021, 12(3), 445; https://doi.org/10.3390/genes12030445
Full text available online: https://www.mdpi.com/2073-4425/12/3/445

4. “Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update”
by Motorin, Y. and Marchand, V.
Genes 2021, 12(2), 278; https://doi.org/10.3390/genes12020278
Full text available online: https://www.mdpi.com/2073-4425/12/2/278

5. “Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women”
by Monticelli, M., Hay Mele, B., Benetti, E., Fallerini, C., Baldassarri, M., Furini, S., Frullanti, E., Mari, F., GEN-COVID Multicenter Study, and Andreotti, G. et al. 
Genes 2021, 12(4), 596; https://doi.org/10.3390/genes12040596
Full text available online: https://www.mdpi.com/2073-4425/12/4/596

6. “Drugging the Undruggable: Advances on RAS Targeting in Cancer”
by Molina-Arcas, M., Samani, A., and Downward, J.
Genes 2021, 12(6), 899; https://doi.org/10.3390/genes12060899
Full text available online: https://www.mdpi.com/2073-4425/12/6/899

7. “Epigenetic Evolution of ACE2 and IL-6 Genes: Non-Canonical Interferon-Stimulated Genes Correlate to COVID-19 Susceptibility in Vertebrates”
by Sang, E. R., Tian, Y., Miller, L. C., and Sang, Y.
Genes 2021, 12(2), 154; https://doi.org/10.3390/genes12020154
Full text available online: https://www.mdpi.com/2073-4425/12/2/154

8. “Novel Approaches to Epigenetic Therapies: From Drug Combinations to Epigenetic Editing”
by Majchrzak-Celińska, A., Warych, A. and Szoszkiewicz, M.
Genes 2021, 12(2), 208; https://doi.org/10.3390/genes12020208
Full text available online: https://www.mdpi.com/2073-4425/12/2/208

9. “The Role of Lipid Sensing Nuclear Receptors (PPARs and LXR) and Metabolic Lipases in Obesity, Diabetes and NAFLD”
by Dixon, E. D., Nardo, A. D., Claudel, T. and Trauner, M.
Genes 2021, 12(5), 645; https://doi.org/10.3390/genes12050645
Full text available online: https://www.mdpi.com/2073-4425/12/5/645 

10. “Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station Using Nanopore Sequencing”
by Stahl-Rommel, S., Jain, M., Nguyen, H. N., Arnold, R. R., Aunon-Chancellor, S. M., Sharp, G. M., Castro, C. L., John, K. K., Juul, S., and Turner, D. J. et al.
Genes 2021, 12(1), 106; https://doi.org/10.3390/genes12010106
Full text available online: https://www.mdpi.com/2073-4425/12/1/106

Peer Review Week began 19 September 2022 under the theme of “Research Integrity: Creating and Supporting Trust in Research”. Through various blog articles, podcast, and webinar, we discussed this crucial subject throughout the week, celebrating the essential role peer review plays in maintaining research quality.

To begin, we held a Webinar on the topic. Professor Peter W. Choate and Dr. Emmanuel Obeng-Gyasi joined Dr. Ioana Craciun, one of MDPI’s scientific officers, for an in-depth discussion.

We invite you to view the event recording:

During the week, the MDPI Blog in a series articles highlighted how good Peer Review safeguards research integrity. The following topics were covered:

• Peer Review Week 2022
• Research Integrity
• What We’ve Learned About Peer Review Reports
• 4 Steps to the Perfect Peer Review Report
• How to Write the Perfect Peer Review Report: An Interview
• Inviting Great Peer Reviewers

In a new edition of Insight Faster, an MDPI podcast, we were delighted to talk to the co-chairs of the Peer Review Week committee, Jayashree Rajagopalan (Senior Manager of Global Community Engagement for CACTUS) and Danielle Padula (Head of Marketing and Community Development at Scholastica) to get their take on this year’s event and its related topics.

You can find the Podcast here.

We hope you enjoy the contents!

Date: 6 October 2022
Time: 4:30 p.m. CEST | 10:30 a.m. EDT | 10:30 p.m. CST Asia
Webinar ID: 875 9531 5334
Webinar Secretariat: genes.webinar@mdpi.com
Webinar Link：https://genes-2.sciforum.net/
Register for free here:
https://us02web.zoom.us/webinar/register/6016617624627/WN_qHhc0H22QG6cIUFwSalY1w

Chair

Prof. Dr. Ponnazhagan is a trained molecular geneticist with a focus on cancer. He is currently a Full Professor and holds an Endowed Professorship in Experimental Cancer Therapeutics. The major research areas of Dr. Ponnazhagan’s lab are experimental cancer therapeutics, including stem cell and gene therapy using adeno-associated virus (AAV), tumor microenvironment (TME), and cancer–bone metastasis. In reference to cancer–bone interaction, Dr. Ponnazhagan’s lab models breast cancer to adopt strategies that target tumor cells, immune suppression, and aggressive osteoclast functions. To overcome the limitations in current therapies, his lab developed novel molecular tools and targeted delivery mechanisms, utilizing mesenchymal stem cells as effective therapeutic vehicles for bone remodeling in breast cancer osteolytic pathology. Towards targeting the receptor activator of nuclear factor kappa-B ligand (RANKL) activation using osteoprotegerin (OPG), a decoy receptor for RANKL, without interfering in tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of tumor cells, his lab developed an OPG mutant by structural protein engineering that lacks TRAIL binding affinity and validated in vivo in a disseminated osteolytic malignancy model. His group is the first to identify a subset of immature myeloid cells, known as myeloid-derived suppressor cells, in the TME within the bone, that directly undergo osteoclast differentiation and serve as osteoclast progenitors to enhance bone damage. Recent studies from his lab have established the role of RANKL in activating M2 macrophages in the breast cancer microenvironment and have shown that dampening the effects of elevated RANKL using the OPG mutant resulted in a shift in the immune milieu favoring an anti-tumor cytokine and chemokine response.

Invited Speakers

Dr. Bodamer was recruited to Boston Children’s Hospital in 2015 as Associate Chief for Genetics and Genomics, where he also has an established translational research laboratory. He is a member of several editorial and scientific advisory boards as well as of patient organizations. Dr. Bodamer has a busy clinical practice at Boston Children’s Hospital where he sees patients of all age groups with complex genetic disorders, including Kabuki syndrome and other disorders of histone modification. In 2017, he founded the Roya Kabuki Program at Boston Children’s Hospital with a focus on integrated clinical care and research to improve health outcomes and identify novel therapies. In addition, Dr. Bodamer is active in several areas of translational genetics and genomics research, in clinical trials and in educational and teaching activities within Harvard Medical School, and he is also an associate member of the Broad Institute of Harvard University and MIT. Since 2021, he has directed the NORD center of excellence for rare diseases at Boston Children’s Hospital.

Dr. Isa Houwink was born on 13 December 1973 in Haarlem, the Netherlands. After she received secondary education at the Barlaeus Gymnasium in Amsterdam, the Netherlands, she successfully passed the Propadeutics in Health Sciences. After obtaining her medical degree in 2003, she started working as a resident at the departments of Obstetrics and Gynecology both in Amsterdam and in Heerlen. She then decided to become a General Practitioner to be able to foster a more personal relationship with her patients and started her residency in Maastricht in 2005. In 2006, she published an accredited written Accredidact CPD module on pre- and postnatal screening together with Prof. Martina Cornel. In 2010, they also published a book on “Genetics in general practice” published by Elsevier in the series of Praktikum Huisartsgeneeskunde. From 2008 until 2013 Dr. Houwink participated in a Ph.D. project in the section Community Genetics, Department of Clinical Genetics (VU University Medical Center Amsterdam) under the supervision of Prof. Martina Cornel and Prof. Geert Jan Dinant (Department of Family Medicine in Maastricht). Her project, funded by the CSG Centre for Society and the Life Sciences /Centre for Medical Systems Biology, aimed to reflect on current genomics developments with primary care workers and to help them identify their learning priorities. On the 20th of December 2013, she defended her thesis "Training in genetics and genomics" Cum Laude. Dr. Houwink worked as an Associate Professor ((Pharmaco)genetics in primary care) at the Leiden University Medical Center and a GP in Kerkrade (GC Terwinselen). In Leiden, her focus was on interprofessional education, (pharmaco)genetics education, implementation and research in primary care, personal genetic lockers, and providing non-genetic healthcare workers clear guidelines and definitions of their responsibilities and roles in addressing genetic risk profiles (common and rare diseases), and she is a member of the Netherlands eHealth Living Lab (NeLL).

We look forward to your participation in this event.

Genes Editorial Office

MDPI will be attending ASHG 2022, held in Los Angeles, USA, from 25 to 29 October 2022.

The following MDPI journals will be represented:

• Genes;
• JPM;
• Biomedicines;
• Biomolecules;
• Cardiogenetics;
• Cancers;
• Brain Science;
• Symmetry;
• Diagnostics;
• Metabolites;
• Cells;
• Biology;
• Humans;
• DNA.

If you plan on attending this conference, feel free to stop by our booth: #1844. Our delegates look forward to meeting you in person to answer any questions you may have.

For more information about the conference, please see the following link:

https://www.ashg.org/meetings/2022-annual-meeting/.

On behalf of the Organizing Committee, it is our pleasure to invite scientists, academicians, young researchers, and students from all over the world to attend the International Conference Single Cell Genomics Moving Forward and present their research. This conference will be held as a three-day event in Barcelona, Spain, from 29 to 31 March 2023.

Our goal in holding this conference is to facilitate innovative collaborative research on the interface of single-cell genomics, spatial transcriptomics, and artificial intelligence. The demand for integrating these fields is quickly growing, and by bringing together multi-disciplinary groups of scientists to present and exchange breakthrough ideas, we hope to stimulate advances in the single-cell research field.

Our program includes keynote lectures, invited talks, workshops, and collaborative discussion sessions on recent outstanding achievements made in single-cell research. In particular, we will focus on identifying future trends and the needs of the field and on proposing and discussing innovative interdisciplinary approaches to address them.

This conference is initiated and sponsored by the journal Genes (ISSN: 2073-4425, IF: 4.141) with the goal of establishing a regular event to provide a venue for initiating collaboration, and discussing the latest achievements and challenges in single-cell biology. We hope to inspire young scientists to join this emerging and exciting field.

We are inviting researchers, experts, students, as well as innovative businesses focusing on any aspect of single-cell multi-omics technologies and analysis, the use of artificial intelligence in single-cell genomics, and spatial genomics and transcriptomics to attend and present their research and products. It is only through an exchange of the widest variety of research possible that we can offer the best forward-thinking solutions in this challenging field. Furthermore, all presenters at the conference will be encouraged to submit a full manuscript of their presentation for consideration for publication in a Special Issue of Genes.

We look forward to meeting you and discussing your exciting single-cell research in the beautiful city of Barcelona!

Genes 2023 Conference Chairs
Professor J. Peter W. Young and Dr. Anelia Horvath

MDPI will be attending SEBBM 2022, held in Malaga, Spain, from 6 to 9 September 2022.

The following MDPI journals will be represented:

• Genes (leading journal);
• Biomolecules (co-leading);
• Cells (co-leading);
• Marine Drugs;
• JFB;
• Biochem;
• CIMB;
• Metabolites;
• Proteomes;
• IJMS.

If you plan on attending this conference, feel free to stop by our booth #25. Our delegates look forward to meeting you in person to answer any questions you may have.

We are pleased to announce that the European Worm Meeting 2022 (EWM 2022) has set up a free media partnership with Genes (ISSN: 2073-4425).

Conference: European Worm Meeting 2022 (EWM 2022)
Date: 27–30 July 2022
Place: University of Vienna, Austria

The 2022 European Worm Meeting (EWM) will take place in the wonderful city of Vienna from 27 to 30 July.

The meeting is hosted by the University of Vienna and will take place at the Lecture Hall of the Campus of the University of Vienna. The University Campus is located near the historic center and is easily accessible by public transport, which means that visitors will have the opportunity not just to attend our event and partake in the sharing of recent research developments and high-quality, but also to experience our beautiful city.

We look forward to an exciting in-person meeting which will offer attendees the opportunity to network with C. elegans researchers from across Europe and beyond.

Further details can be found on the event’s website: https://ewm2022.univie.ac.at/.

Genes Editorial Office

The Genes Editorial Office is pleased to inform you that applications are open for the Topical Advisory Panel. Should you decide to serve on the Topical Advisory Panel, you would be responsible for some of the following tasks, depending on your availability:

• Providing regular reviews of manuscripts;
• Setting up at least one Special Issue in partnership with a senior researcher within two years of your appointment and proposing a detailed strategy plan for the Special Issue (including soliciting papers, promoting the Special Issue, etc.);
• Providing support for Special Issues/Topics related to your expertise when their Guest Editor(s) are not available. This includes Special Issue promotion via social media and giving advice on some scientific matters;
• Promoting our journal at conferences (adding 1–2 slides into your presentation, distributing flyers, recommending the journal to your colleagues, etc.), on social media, and other relevant platforms;
• Working with Editorial Board Members or the Editorial Office to promote high-quality/featured papers (for example, writing summaries or highlights for editor-selected papers).

To qualify as a Topical Advisory Panel Member, applicants must:

• Have expertise and experience in a field related to Genes;
• Have completed their Ph.D. within the last approximately 10 years;
• Have at least 6 papers published in the last 5 years as a first author or corresponding author;
• Currently hold an independent research position in academia or at a government institute.

Each year, members’ performance is evaluated, and outstanding members are promoted to the Editorial Board by the Editor-in-Chief. Please visit the following link to submit your application: https://www.mdpi.com/journal/genes/topical_advisory_panel.

Please do not hesitate to contact the Editorial Office (genes@mdpi.com) for further details and clarification.

Genes Editorial Office

The 2021 citation metrics have been released in the Journal Citation Reports (JCR), and we’re pleased to announce the following results for MDPI journals:

For more information on Impact Factors and what it means to index academic journals, please visit our related blog posts.

* Journals given their first Impact Factor in 2022

Source: 2021 Journal Impact Factors, Journal Citation Reports ^TM (Clarivate, 2022)

We are pleased to announce the launch of a new initiative—the Special Issue Mentor Program.

This program will provide an opportunity for early career scientists to enhance their editing, networking, and organizational skills and work closely with our journal to gain editorial experience. Early career scientists with novel ideas for new Genes Special Issues will act as Guest Editors under the mentorship of an experienced scientist; this mentor may be a member of the Editorial Board of Genes (ISSN 2073–4425) or from other well-established research institutes or laboratories.

The mentee’s responsibilities include:

• Providing a CV, including a list of publications;
• Proposing a Special Issue title and a short introduction;
• Writing a brief promotion plan for the Special Issue;
• Writing an editorial for the online edition of the Special Issue;
• Reviewing and issuing decisions for submissions under the mentorship of our Editorial Board Members.

The mentor’s responsibilities include:

• Conducting a final check before the Special Issue is published online;
• Co-editing the Special Issue with younger scholars and performing quality control for its publications;
• Advising younger scholars if they have doubts or concerns regarding submissions;
• Organizing regular video calls with young scholars and the office to discuss problems and suggestions for the Special Issue.

Certificates and awards:

After the Special Issue closes, the Editorial Office will provide certificates for all of the mentors. The program scholars will be prioritized as candidates for Genes Young Investigator Awards in future editions.

If you are interested in this opportunity, please send your Special Issue proposal to the Genes Editorial Office (genes@mdpi.com), and we will discuss the process (mentor collaboration, Special Issue topic feasibility analysis, etc.) in further detail.

In addition to the new Special Issue Mentor Program, Genes will continually welcome all Special Issue proposals based on hot research topics.

Genes Editorial Office

The 2021 citation metrics have been officially released in Scopus!

We are pleased to announce that 182 MDPI journals are included, of which:

● 21 journals received their first CiteScore.
● 85% of journals increased their CiteScore from 2020.
● 155 journals (85%) ranked above average, in at least one category.

The following 65 MDPI journals (36%) ranked among the top 25% of journals, in at least one category:

Source: 2021 CiteScores™ (Elsevier)

MDPI will be attending 2022 International Symposium on Rapeseed Genomic Breeding, held in Wuhan, China, 23–24 June 2022.

Conference: 2022 International Symposium on Rapeseed Genomic Breeding
Website: http://yanglab.hzau.edu.cn/meeting_2022/index.html
Date: 23–24 June 2022
Place: Wuhan, China

As the world population grows and the climate changes, we are facing limitations and challenges related to food and energy supply. Thus, innovations in plant breeding are required to further boost the yield potential of crops and to meet the increasing demands for food and nonfood in the future. Rapeseed (Brassica napus) is an important oil crop that provides edible oil, vegetables, animal fodder, green manure, and biodiesel for life and industry worldwide, contributing significantly to ensuring global food security and economic development.

During the last decade, plant scientists working on rapeseed have benefited from the development of new technologies, including high-throughput phenotyping, third-generation sequencing, genome editing, whole genomic selection, and de novo domestication, which have been used to investigate and achieve substantial understanding of the rapeseed genome and to identify genes regulating key agronomic characteristics. Novel breeding strategies, such as speed breeding, have been developed and are being applied to overcome the limiting factors of conventional rapeseed breeding.

This symposium aims to bring together researchers and breeders, particularly those who work on rapeseed (and related species), from around the world to share and discuss cutting-edge research, the latest breeding practices, and future breeding perspectives.

The topics covered will include but are not limited to the following: (1) rapeseed genome, epigenome, and 3D genome; (2) novel genetic diversity and genomic selection; (3) genetic control of valuable agronomic traits; (4) Brassica clubroot disease; (5) transgenesis, genome editing, and novel breeding strategies; (6) prospects on future Brassica/crop breeding.

We warmly invite you to attend and participate in this meeting and look forward to welcoming you!

The following MDPI journals will be represented:

• Genes
• Agriculture
• Agronomy
• Plants
• Horticulturae
• Epigenomes
• Crops

If you are also attending this conference, feel free to stop by our booth (Booth #1). Our delegates look forward to meeting you in person to answer any questions you may have. For more information about the conference, please visit the following link:
http://yanglab.hzau.edu.cn/meeting_2022/index.html

Genes Editorial Office

In order to acknowledge our reviewers, who so generously dedicate their time to reviewing papers and demonstrate diligence, professionalism, and timeliness when reviewing manuscripts, MDPI journals regularly offer outstanding reviewer awards to scholars who participate in the peer-review process.

We are proud to recognize winners for the year 2021 in the “Biology & Life Sciences” category for their outstanding contributions among extensive competition by presenting them with an Outstanding Reviewer Award.

We would like to take this opportunity to congratulate all the winners on their achievement.

MDPI will continue to provide support and recognition to the academic community.

Biology:

• Enrico Vito Perrino, CIHEAM, Mediterranean Agronomic Institute of Bari, Italy
• Dhirendra Kumar, National Institute of Environmental Health Sciences, Research Triangle Park, USA
• Carlos A. Viegas, Univesity of Trás-os-Montes e Alto Douro, Portugal
• Yuri Shavrukov, Flinders University, Australia
• Bipin Gaihre, Mayo Clinic, USA

Brain Sciences:

• Craig D. Workman, University of Iowa, USA
• Vivian Ciaramitaro, University of Massachusetts Boston, USA
• Yang Zhang, University of Minnesota, USA

Cells:

• Bonam Srinivasa Reddy, Université de Paris, France
• Homma Takujiro, Yamagata University, Japan
• Hwang, In Koo, Seoul National University, South Korea
• Kobeissy Firas, University of Florida, USA
• Rebelo, Sandra, University of Aveiro, Portugal

Diversity:

• Günter Gollmann, University of Vienna, Austria
• Stephan Koblmüller, University of Graz, Austria
• Emiliano Mori, Istituto di Ricerca sugli Ecosistemi Terrestri, Italy

Horticulturae:

• Joshua D. Klein, Agricultural Research Organization—The Volcani Center, Israel
• Ana Cristina S Figueiredo, Faculdade de Ciências da Universidade de Lisboa, Portugal

Insects:

• Carmelo Peter Bonsignore, Università Mediterranea di Reggio Calabria, Italy
• Klaus H. Hoffmann, University of Bayreuth, Germany
• Ivan Milosavljević, University of California, USA

Metabolites:

• Remigiusz Bachor, University of Wrocław, Poland
• Nguyen Phuoc Long, Inje University College of Medicine, South Korea
• Chi Chen, University of Minnesota, USA

Nutrients:

• Jadwiga Hamułka, Warsaw University of Life Sciences, Poland
• Grace Campbell, University of Sydney, Australia
• Nicholas Norwitz, Harvard Medical School, USA
• Stefan Kabisch, Charité University Hospital Berlin, Germany
• Luis Rodrigo, University of Oviedo, Spain

Veterinary Sciences:

• Carlos Viegas, Univesity of Trás-os-Montes e Alto Douro, Portugal
• Arvind Sharma, The University of Queensland, Australia

MDPI’s Young Investigator Awards recognize promising junior researchers, acknowledge their contributions, and enhance communication among scientists. We are proud to present the 2021 winners in the “Biology & Life Sciences” category. The winners were selected by the journals’ editors.

We warmly congratulate the awarded young investigators for their outstanding contributions.

MDPI will continue to provide support and recognition to the academic community.

Agriculture:

• Carlos Guzmán, University of Cordoba, Spain

Animals:

• Katharina Hohlbaum, Freie Universität Berlin, Germany

Cells:

• Uri Ben-David, Tel Aviv University, Israel

Diversity:

• Enrico Lunghi, Institute of Zoology Chinese Academy of Sciences in Beijing, China

Foods:

• Guodong Zhang, University of Massachusetts Amherst, USA

Horticulturae:

• Luke Bell, Temperate Horticulture, University of Reading, UK

International Journal of Molecular Sciences:

• Alessandro D’Urso, University of Catania, Italy.
• Apostolos Zaravinos, University of Cyprus, Cyprus
• Cesar de la Fuente-Nunez, University of Pennsylvania, USA
• Maria Teresa Caccamo, Messina University, Italy
• Tiziana Bonifacino, University of Genoa, Italy

Journal of Fungi:

• Federico Baltar, University of Vienna, Austria
• Rebecca Drummond, University of Birmingham, UK
• Miriam Oses-Ruiz, Public University of Navarre, Spain

Life:

• João Pedro da Silva Machado Lobo, University of Porto, Portugal
• Vincenzo Russo, University of Campania Luigi Vanvitelli, Italy

Metabolites:

• Gabriele Rocchetti, Catholic University of Sacred Heart, Italy

Nutrients:

• Fiona Lavelle, Queen's University Belfast, UK
• Matthew Snelson, Monash University, Australia

Pathogens:

• Si Ming Man, Australian National University, Australia
• Jasper Fuk-Woo Chan, University of Hong Kong, China

Plants:

• Stefania Sut, University of Padova, Italy
• Mohamed Ahmed El-Esawi, Tanta University, Tanta, Egypt

Vaccines:

• Nicholas M. Provine, University of Oxford, UK

Viruses:

• Nicholas S. Heaton, Duke University, USA

We are proud to recognize the winners of MDPI’s 2021 Travel Awards in the “Biology & Life Sciences” category for their outstanding presentations and to present them with the prize.

MDPI journals regularly offer travel awards to encourage talented junior scientists to present their latest research at academic conferences in specific fields, which helps to increase their influence.

The winners mentioned below were carefully selected by the journal editors based on an outline of their research and the work to be presented at an academic conference.

We would like to warmly congratulate the winners of 2021 Travel Awards and wish them the greatest success with their future research endeavors. MDPI will continue to enhance communication among scientists.

Agriculture:

• Zahra Bitarafan, Norwegian Institute of Bioeconomy Research (NIBIO), Norway
• Nikolaos Tsoulias, Leibniz Institute for Agricultural Engineering and Bioeconomy (ATB), Germany

Fermentation:

• Michela Verni, University of Bari, Italy
• Philipp Demling, RWTH Aachen University, Germany

Horticulturae:

• Jagveer Singh, Punjab Agricultural University, India
• Ibrar Hussain, State University of Londrina, Brazil

Microorganisms:

• Francis Muchaamba, University of Zurich, Switzerland

Methods and Protocols:

• Tanja Eisemann, SBP Medical Discovery Institute, USA

Nutrients:

• Mrinalini Dey, National Institute for Health Research, UK
• Ben Kirk, University of Melbourne, Australia
• Kirrilly Pursey, University of Newcastle, Australia
• Dieuwertje Kok, Wageningen University, the Netherlands
• Hanna Huber, University of Bonn, Germany
• Marlene Lages, University of Porto, Portugal
• Zohra S. Lassi, University of Adelaide, Australia
• Rik Olde Engberink, Amsterdam University Medicial Center, the Netherlands
• Sarah Warkentin, University of Porto (ISPUP), Portugal
• Álvaro Hernáez, Norwegian Institute of Public Health, Norway
• Leila Abdelhamid, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, USA
• Maria Michela Cesare, University of Siena, Italy
• Kaisa Hiippala, University of Helsinki, Finland

Pathogens:

• Vanessa Silva, University of Trás-os-Montes and Alto Douro, Portugal
• Hejun Liu, Scripps Research Institute, USA
• Tomokazu Tamura, Princeton University, USA

Toxins:

• Cecilie Knudsen, Technical University of Denmark, Denmark
• Laura Biessy, Cawthron Institute, New Zealand
• Marcelo Mendes Rabelo, University of Florida, USA

Vaccines:

• Hee Chun Chung, Seoul National University, South Korea
• Alejandro Marin Lopez, Yale University, USA

The purpose of our Best Paper Awards is to promote and recognize the most impactful contributions published within MDPI journals.

The editors of each journal carefully selected reviews and research papers through a rigorous judging process based on criteria such as the scientific merit, overall impact, and the quality of presentation of the papers published in the journal last year.

We are honored to present the winners in the subject areas of “Biology & Life Sciences”, who were selected amongst extensive competition, and congratulate the authors for their outstanding scientific publications.

MDPI will continue to provide support and recognition to the academic community.

Animals:

• “Effects of Dietary Betaine on Growth Performance, Digestive Function, Carcass Traitsand Meat Quality in Indigenous Yellow-Feathered Broilers under Long-Term Heat Stress”

by Wenchao Liu, Yilin Yuan, Chenyu Sun, Balamuralikrishnan Balasubramanian, Zhihui Zhao and Lilong An

Animals 2019, 9(8), 506, doi 10.3390/ani9080506

• “The Ethics of Human–Animal Relationships and Public Discourse: A Case Study of Lions Bred for Their Bones”

by Peter Coals, Dawn Burnham, Andrew Loveridge, David W. Macdonald, Michael ’t Sas-Rolfes, Vivienne L. Williams and John A. Vucetich

Animals 2019, 9(2), 52; doi 10.3390/ani9020052

• “The Potential Role of Insects as Feed: A Multi-Perspective Review”

by Giovanni Sogari, Mario Amato, Ilaria Biasato, Silvana Chiesa and Laura Gasco

Animals 2019, 9(4), 119; doi 10.3390/ani9040119

Antibodies:

• “Antibody Structure and Function: The Basis for Engineering Therapeutics”

by Mark L. Chiu; Dennis R. Goulet; Alexey Teplyakov and Gary L. Gilliland

Antibodies 2019, 8(4), 55; doi 10.3390/antib8040055

Antioxidants:

• “Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway”

by Luca Frattaruolo, Gabriele Carullo, Matteo Brindisi, Sarah Mazzotta, Luca Bellissimo, Vittoria Rago, Rosita Curcio, Vincenza Dolce, Francesca Aiello and Anna Rita Cappello

Antioxidants 2019, 8(6), 186; doi 10.3390/antiox8060186

• “LC-ESI-QTOF/MS Characterisation of Phenolic Acids and Flavonoids in Polyphenol-Rich Fruits and Vegetables and Their Potential Antioxidant Activities”

by Chunhe Gu, Kate Howell, Frank R. Dunshea and Hafiz A. R. Suleria

Antioxidants 2019, 8(9), 405; doi 10.3390/antiox8090405

• “Nutritional Value, Chemical Composition and Cytotoxic Properties of Common Purslane (Portulaca oleracea L.) in Relation to Harvesting Stage and Plant Part”

by Spyridon A. Petropoulos, Ângela Fernandes, Maria Inês Dias, Ioannis B. Vasilakoglou, Konstantinos Petrotos, Lillian Barros and Isabel C. F. R. Ferreira

Antioxidants 2019, 8(8), 293; doi 10.3390/antiox8080293

• “A Comprehensive Review on Lipid Oxidation in Meat and Meat Products”

by Rubén Domínguez, Mirian Pateiro, Mohammed Gagaoua, Francisco J. Barba, Wangang Zhang and José M. Lorenzo

Antioxidants 2019, 8(10), 429; doi 10.3390/antiox8100429

Biology:

• “The Mammalian Circadian Timing System and the Suprachiasmatic Nucleus as Its Pacemaker”

by Michael H. Hastings, Elizabeth S. Maywood and Marco Brancaccio

Biology 2019, 8(1), 13; doi 10.3390/biology8010013

• “Combined Effects of Acute Temperature Change and Elevated pCO₂ on the Metabolic Rates and Hypoxia Tolerances of Clearnose Skate (Rostaraja eglanteria), Summer Flounder (Paralichthys dentatus), and Thorny Skate (Amblyraja radiata)”

by Gail D. Schwieterman, Daniel P. Crear, Brooke N. Anderson, Danielle R. Lavoie, James A. Sulikowski, Peter G. Bushnell and Richard W. Brill

Biology 2019, 8(3), 56; doi 10.3390/biology8030056

Biomolecules:

• “Flagella-Driven Motility of Bacteria”

by Shuichi Nakamura and Tohru Minamino

Biomolecules 2019, 9(7), 279; doi 10.3390/biom9070279

• “Systematic FTIR Spectroscopy Study of the Secondary Structure Changes in Human Serum Albumin under Various Denaturation Conditions”

by Dmitrii Usoltsev, Vera Sitnikovaandrey Kajava and Mayya Uspenskaya

Biomolecules 2019, 9(8), 359; doi 10.3390/biom9080359

• “Quantification of Fecal Short Chain Fatty Acids by Liquid Chromatography Tandem Mass Spectrometry—Investigation of Pre-Analytic Stability”

by Gerhard Liebisch, Josef Ecker, Sebastian Roth, Sabine Schweizer, Veronika Öttl, Hans-Frieder Schött, Hongsup Yoon, Dirk Haller, Ernst Holler, Ralph Burkhardt and Silke Matysik

Biomolecules 2019, 9(4), 121; doi 10.3390/biom9040121

• “Cytotoxicity of Dendrimers”

by Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska and Barbara Klajnert-Maculewicz

Biomolecules 2019, 9(8), 330; doi 10.3390/biom9080330

Cells:

• “Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models”

by Heng Sheng Sow, Jiang Ren, Marcel Camps, Ferry Ossendorp and Peter ten Dijke

Cells 2019, 8(4), 320; doi 10.3390/cells8040320

• “Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy”

by Dinender K. Singla, Taylor A. Johnson and Zahra Tavakoli Dargani

Cells 2019, 8(10), 1224; doi 10.3390/cells8101224

• “Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis”

by Laura M. Doyle and Michael Zhuo Wang

Cells 2019, 8(7), 727; doi 10.3390/cells8070727

• “Mesenchymal Stem Cells for Regenerative Medicine”

by Yu Han, Xuezhou Li, Yanbo Zhang, Yuping Han, Fei Chang and Jianxun Ding

Cells 2019, 8(8), 886; doi 10.3390/cells8080886

Genes:

• “A High-Quality De novo Genome Assembly from a Single Mosquito Using PacBio Sequencing”

by Sarah B. Kingan, Haynes Heaton, Juliana Cudini, Christine C. Lambert, Primo Baybayan, Brendan D. Galvin, Richard Durbin, Jonas Korlach and Mara K. N. Lawniczak

Genes 2019, 10(1), 62; doi 10.3390/genes10010062

• “Eukaryotic 5-methylcytosine (m⁵C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease”

by Katherine E Bohnsack, Claudia Höbartner and Markus T Bohnsack

Genes 2019, 10(2), 102; doi 10.3390/genes10020102

• “Tree Lab: Portable Genomics for Early Detection of Plant Viruses and Pests in Sub-Saharan Africa”

by Laura M. Boykin, Peter Sseruwagi, Titus Alicai, Elijah Ateka, Ibrahim Umar Mohammed, Jo-Ann L. Stanton, Charles Kayuki, Deogratius Mark, Tarcisius Fute, Joel Erasto, Hilda Bachwenkizi, Brenda Muga, Naomi Mumo, Jenniffer Mwangi, Phillip Abidrabo, Geoffrey Okao-Okuja, Geresemu Omuut, Jacinta Akol, Hellen B. Apio, Francis Osingada, Monica A. Kehoe, David Eccles, Anders Savill, Stephen Lamb, Tonny Kinene, Christopher B. Rawle, Abishek Muralidhar, Kirsty Mayall, Fred Tairo and Joseph Ndunguru

Genes 2019, 10(9), 632; doi 10.3390/genes10090632

• “Transcription Factors Associated with Abiotic and Biotic Stress Tolerance and Their Potential for Crops Improvement”

by Elamin Hafiz Baillo, Roy Njoroge Kimotho, Zhengbin Zhang and Ping Xu

Genes 2019, 10(10), 771; doi 10.3390/genes10100771

Horticulturae:

• “Recent Advances in Hormonal Regulation and Cross-Talk during Non-Climacteric Fruit Development and Ripening”

by Lida Fuentes, Carlos R. Figueroa and Monika Valdenegro

Horticulturae 2019, 5(2), 45; doi 10.3390/horticulturae5020045

• “Evaluation of Two Wild Populations of Hedge Mustard (Sisymbrium officinale (L.) Scop.) as a Potential Leafy Vegetable”

by Marta Guarise, Gigliola Borgonovo, Angela Bassoli and Antonio Ferrante

Horticulturae 2019, 5(1), 13; doi 10.3390/horticulturae5010013

Insects:

• “Olfactory Preference of Drosophila suzukii Shifts between Fruit and Fermentation Cues over the Season: Effects of Physiological Status”

by Rik Clymans, Vincent Van Kerckvoorde, Eva Bangels, Wannes Akkermans, Ammar Alhmedi, Patrick De Clercq, Tim Beliën and Dany bylemans

Insects 2019, 10(7), 200; doi 10.3390/insects10070200

• “Telenomus remus, a Candidate Parasitoid for the Biological Control of Spodoptera frugiperda in Africa, is already Present on the Continent”

by Marc Kenis, Hannalene du Plessis, Johnnie Van den Berg, Malick Niango Ba, Georg Goergen, Koffi Eric Kwadjo, Ibrahim Baoua, Tadele Tefera, Alan Buddie, Giovanni Cafà, Lisa Offord, Ivan Rwomushana and Andrew Polaszek

Insects 2019, 10(4), 92; doi 10.3390/insects10040092

• “Symbiotic Plant Biomass Decomposition in Fungus-Growing Termites”

by Rafael R. da Costa, Haofu Hu, Hongjie Li and Michael Poulsen

Insects 2019, 10(4), 87; doi 10.3390/insects10040087

International Journal of Molecular Sciences:

• “Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks”

by Rüdiger Hardeland

Int. J. Mol. Sci. 2019, 20(5), 1223; doi 10.3390/ijms20051223

• “Causative Links between Protein Aggregation and Oxidative Stress: A Review”

by Elise Lévy, Nadine El Banna, Dorothée Baïlle, Amélie Heneman-Masurel, Sandrine Truchet, Human Rezaei, Meng-Er Huang, Vincent Béringue, Davy Martin and Laurence Vernis

Int. J. Mol. Sci. 2019, 20(16), 3896; doi 10.3390/ijms20163896

• “Immunobiology of Atherosclerosis: A Complex Net of Interactions”

by Beatriz Herrero-Fernandez, Raquel Gomez-Bris, Beatriz Somovilla-Crespo and Jose Maria Gonzalez-Granado

Int. J. Mol. Sci. 2019, 20(21), 5293; doi 10.3390/ijms20215293

• “Development of a Gut-on-a-Chip Model for High Throughput Disease Modeling and Drug Discovery”

by Claudia Beaurivage, Elena Naumovska, Yee Xiang Chang, Edo D. Elstak, Arnaud Nicolas, Heidi Wouters, Guido van Moolenbroek, Henriëtte L. Lanz, Sebastiaan J. Trietsch, Jos Joore, Paul Vulto, Richard A.J. Janssen, Kai S. Erdmann, Jan Stallen and Dorota Kurek

Int. J. Mol. Sci. 2019, 20(22), 5661; doi 10.3390/ijms20225661

• “Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammationand Angiogenesis”

by Maiko Okano, Masanori Oshi, Ali Linsk Butash, Eriko Katsuta, Kazunoshin Tachibana, Katsuharu Saito, Hirokazu Okayama, Xuan Peng, Li Yan, Koji Kono, Toru Ohtake and Kazuaki Takabe

Int. J. Mol. Sci. 2019, 20(17), 4197; doi 10.3390/ijms20174197

• “CGRP Induces Differential Regulation of Cytokines from Satellite Glial Cells in Trigeminal Ganglia and Orofacial Nociception”

by Shaista Afroz, Rieko Arakaki, Takuma Iwasa, Masamitsu Oshima, Maki Hosoki, Miho Inoue, Otto Baba, Yoshihiro Okayama and Yoshizo Matsuka

Int. J. Mol. Sci. 2019, 20(3), 711; doi 10.3390/ijms20030711

Life:

• “Characterization of Resistance in Gram-Negative Urinary Isolates Using Existing and Novel Indicators of Clinical Relevance: A 10-Year Data Analysis”

by Márió Gajdács, Zoltán Bátori, Marianna Ábrók, Andrea Lázár and Katalin Burián

Life 2020, 10(2), 16; doi 10.3390/life10020016

• “Neuroprotection or Neurotoxicity of Illicit Drugs on Parkinson’s Disease”

by Carla Ferreira, Catarina Almeida, Sandra Tenreiro and Alexandre Quintas

Life 2020, 10(6), 86; doi 10.3390/life10060086

Nutrients:

• “Gut Microbiome: Profound Implications for Diet and Disease”

by Ronald D. Hills, Benjamin A. Pontefract, Hillary R. Mishcon, Cody A. Black, Steven C. Sutton and Cory R. Theberge

Nutrients 2019, 11(7), 1613; doi 10.3390/nu11071613

• “Vitamin C Can Shorten the Length of Stay in the ICU: A Meta-Analysis”

by Harri Hemilä and Elizabeth Chalker

Nutrients 2019, 11(4), 708; doi 10.3390/nu11040708

• “Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans”

by Humaira Jamshed, Robbie A. Beyl, Deborah L. Della Manna, Eddy S. Yang, Eric Ravussin and Courtney M. Peterson

Nutrients 2019, 11(6), 1234; doi 10.3390/nu11061234

Pathogens:

• “Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome”

by Israr Kha, Naeem Ullah, Lajia Zha, Yanrui Bai, Ashiq Khan, Tang Zhao, Tuanjie Che and Chunjiang Zhang

Pathogens 2019, 8(3), 126; doi 10.3390/pathogens8030126

• “Candida albicans Interactions with Mucosal Surfaces during Health and Disease”

by Spyridoula-Angeliki Nikou,Nessim Kichik, Rhys Brown, Nicole O. Ponde, Jemima Ho, Julian R. Naglik and Jonathan P. Richardson

Pathogens 2019, 8(2), 53; doi 10.3390/pathogens8020053

• “Bacteriophages in Natural and Artificial Environments”

by Steven Batinovic, Flavia Wassef, Sarah A. Knowler, Daniel T.F. Rice, Cassandra R. Stanton, Jayson Rose, Joseph Tucci, Tadashi Nittami, Antony Vinh, Grant R. Drummond, Christopher G. Sobey, Hiu Tat Chan, Robert J. Seviour, Steve Petrovski and Ashley E. Franks

Pathogens 2019, 8(3), 100; doi 10.3390/pathogens8030100

Plants:

• “Plant Disease Detection and Classification by Deep Learning”

by Muhammad Hammad Saleem, Johan Potgieter and Khalid Mahmood Arif 

Plants 2019, 8(11), 468; doi 10.3390/plants8110468

• “Involvement of Phenolic Acids in Short-Term Adaptation to Salinity Stress is Species-Specific among Brassicaceae”

by Ida Linić, Dunja Šamec, Jiří Grúz, Valerija Vujčić Bok, Miroslav Strnad and Branka Salopek-Sondi

Plants 2019, 8(6), 155; doi 10.3390/plants8060155

• “Isoform-Specific NO Synthesis by Arabidopsis thaliana Nitrate Reductase”

by Marie Agatha Mohn, Besarta Thaqi and Katrin Fischer-Schrader

Plants 2019, 8(3), 67; doi 10.3390/plants8030067

• “GWAS for Starch-Related Parameters in Japonica Rice (Oryza sativa L.)”

by Chiara Biselliandrea Volante, Francesca Desiderio, Alessandro Tondelli, Alberto Gianinetti, Franca Finocchiaro, Federica Taddei, Laura Gazza, Daniela Sgrulletta, Luigi Cattivelli and Giampiero Valè

Plants 2019, 8(8), 292; doi 10.3390/plants8080292

We are pleased to announce that the 2022 11th International Conference on Bioinformatics and Biomedical Science (ICBBS 2022) has set up a free media partnership with Genes (ISSN: 2073-4425).

Conference: 2022 11th International Conference on Bioinformatics and Biomedical Science (ICBBS 2022)
Date: 28–30 October 2022
Place: Nanning, China

The ICBBS conference series is held annually. Previously, it has been successfully held in Xiamen (online), Beijing, Shenzhen, Bangkok, Kuala Lumpur, Copenhagen, Bali and Singapore. The aim of the ICBBS is to provide a platform for researchers, engineers, academicians and industrial professionals from all over the world to present their research results and development activities in bioinformatics and biomedical science, as well as related fields. This conference provides opportunities for the delegates to exchange new ideas and application experiences face to face, to establish business or research relations, and to find global partners for future collaborations. The submitted conference papers will be reviewed by technical committees of the conference. We would like to invite you to join us for the 2022 11th International Conference on Bioinformatics and Biomedical Science (ICBBS 2022), which is sponsored by Guangxi University. ICBBS 2022 will be held from 28 to 30 October 2022 in Nanning, China.

Further details can be found on the event’s website: http://www.icbbs.org/.

Genes (ISSN: 2073-4425) will be attending the 18th International p53 Workshop, held in Israel, from 22 to 25 May 2022.

The conference is organized by the Weizmann Institute of Science. The 18th International p53 Workshop will bring together experts from diverse backgrounds and provide an exciting platform to discuss the latest discoveries in p53 research, on the road to harnessing basic science toward the development of novel p53-based cancer therapies.

The following MDPI journals will be represented:

• Genes (leading journal);
• Life;
• JPM;
• JCM;
• Medicina;
• Biomedicines;
• Cancers;
• IJMS;
• BioTech;
• BioChem.

If you are attending this conference, feel free to stop by our booth. Our delegates look forward to meeting you in person to answer any questions you may have. For more information about the conference, please see the following link: https://www.weizmann.ac.il/conferences/P53W2020/.

Thank you for your interest.

Genes Editorial Office

To specifically develop different research areas and attract more high-quality papers, Genes has announced 11 new Sections in 2021 (more details can be found at https://www.mdpi.com/journal/genes/sections). At present, the following sections have not yet found suitable scholars to lead them:

• “Toxicogenomics” (https://www.mdpi.com/journal/genes/sections/toxicogenomics);
• “Genes & Environments” (https://www.mdpi.com/journal/genes/sections/genes_environments);
• “Genetic Diagnosis” (https://www.mdpi.com/journal/genes/sections/genetic_diagnosis);
• “Viral Genomics” (https://www.mdpi.com/journal/genes/sections/viral_genomics).

We are now recruiting Section Editors-in-Chief (SEiC) for these four sections. If you are an active researcher in one of the aforementioned fields and are passionate about publishing cutting-edge research, please do not hesitate to get in touch (genes@mdpi.com). You can find more information on our homepage: https://www.mdpi.com/journal/genes.

The Section Editor-in-Chief has the following responsibilities:

• Making decisions on whether a manuscript can be accepted or not based on the reports we collect;
• Reviewing a small number of papers per year and managing the Section together with journal editors;
• Promoting Genes and increasing its visibility at related academic conferences.

Genes (ISSN 2073-4425) is a peer-reviewed, open access journal of genetics and genomics published monthly online by MDPI. Genes is indexed within Scopus, SCIE (Web of Science), PubMed, MEDLINE, PMC, Embase, AGRIOLA, and many other databases.

We believe that by combining our rigorous editorial policies with your expertise, we can build a high-quality journal. We thank you in advance for your interest and look forward to collaborating with you.

Conference: The 2022 IMB Conference

Date: 28 June–01 July 2022

Place: Institute of Molecular Biology (IMB), Mainz, Germany

Aging is a challenge that affects all organisms. To cope with the adversities that cause aging, organisms have evolved protective mechanisms that promote resilience. These range from the molecular (e.g., biophysics of molecules, genetic, and physiological) to the organismic (e.g., division of societal and ecological roles). Recent breakthroughs that have integrated multidisciplinary teams and novel models have opened up exciting new directions at the frontier of aging research. This four-day conference will bring together scientists from all fields with an interest in aging to foster an integrated view of biological resilience during aging. Session topics will focus on the evolution of lifespan, genome stability, germ and stem cells and aging, metabolism and the microbiome, regeneration, stress and aging, and phase separation.

For more information, please visit: www.imb.de/2022ageingconference.

It is our great honor to congratulate the Editorial Board Members and Editors in MDPI's journals who have been distinguished as 2021 Highly Cited Researchers by Clarivate, according to Web of Science data. We herewith express our gratitude for the immense impact the named researchers continue to make on scientific progress and on our journals' development.

Clarivate's annual list of Highly Cited Researchers^TM identifies the most highly cited scientists for the past decade. Their impactful papers are among the top 1 per cent in the citation distribution of one or more of 22 fields analyzed in the "Essential Science Indicators", distinguishing them as hugely influential among their peers.

The full list of 2021 Highly Cited Researchers  can be accessed at the following webpage in the Web of Science^TM https://recognition.webofscience.com/awards/highly-cited/2021/.

--- Highly Cited Researchers (HCR) is a Clarivate product.

Academic editors play a crucial role in leading our journals and ensuring that each article undergoes a robust and timely peer-review. With the launch of Topics this year and addition of Topic Editors to our family of academic editors, we decided it would be a good time to restructure our academic boards, thus providing more clarity and support for each role. MDPI is pleased to announce the launch of a new position—Topical Advisory Panel Member, that will replace the previous position of Topics Board Member. The Topical Advisory Panel will be comprised of early career researchers eager to gain experience in editorial work.

The main responsibility of the new members of the Topical Advisory Panel is to regularly provide support to Guest Editors, Topic Editors, and Section Board Members. The responsibilities of the Topical Advisory Panel are available here: https://www.mdpi.com/editors.

Each year, the members’ performances are evaluated, and outstanding members are promoted to the Editorial Board by the Editor-in-Chief.

To qualify as a Topical Advisory Panel Member, applicants must:

• Have expertise and experience in the field related to the journal;
• Have received a Ph.D. in the last 10 years, approximately;
• Have at least 6-8 published papers in the last 5 years as first author or corresponding author;
• Currently hold an independent research position in academia or a government institute.

If you are interested in this role, please contact the editorial office by email.

We look forward to hearing from you soon.

We are now recruiting Reviewer Board Members (RBMs) for the journal Genes (ISSN: 2073-4425). If you are an active researcher in the field and are passionate about publishing cutting-edge research, do not hesitate to contact the Genes Editorial Office (genes@mdpi.com).

Genes is an international, peer-reviewed, open access journal of genetics and genomics published monthly online by MDPI. Genes is indexed within Scopus, SCIE (Web of Science), PubMed, MEDLINE, PMC, Embase, AGRIOLA, and many other databases. The 2020 impact factor of Genes is 4.096 and the CiteScore is 4.4.

The benefits of joining our Reviewer Board are as follows:

• For each review, you will receive a discount voucher that can be used for reducing the article processing charge (APC) of a future submission to any MDPI journal;
• You may publish one paper per year with a 20% discount after standard peer-review in Genes;
• You will be considered for the journal’s outstanding reviewer award;
• You will receive a personalized reviewer certificate;
• You will have the ability to adjust your review frequency based on your schedule in our system;
• You can verify and showcase your peer review and editorial contributions for our journal.

If you have any questions, suggestions, or recommendations, do not hesitate to let us know. We look forward to working with you.

Founded in 1996, MDPI was one of the first fully Open Access publisher. Over 25 years MDPI has grown to become the largest Open Access publisher globally, publishing over 160,000 articles across more than 350 journals in 2020. At the core, MDPI was founded in response to a pressing need of fast publication and inclusion. The scholar was set at the centre of the publication process for the first time. Acting as a service provider, rather than a product provider, MDPI exists to help scientists achive their objective to disseminate research results. At MDPI, we believe scientists deserve a better service from the publishing world.

The International Open Access Week (Open Access Week), founded by the SPARC (the Scholarly Publishing and Academic Resources Coalition) Alliance and student partners in 2008, has been successfully running for 13 years. As an advocate and pioneer of open access publishing, MDPI actively responds to the call of International Open Access Week. This year’s theme of “It Matters How We Open Knowledge: Building Structural Equity” highlights the Recommendation’s call for equitable participation from all authors and readers.

For the last 25 years, MDPI has been committed to disseminating open research. Here is a video showing MDPI’s Commitment to Equity, Inclusion and Diversity for More than 25 Years.

International Open Access Week is an important opportunity to catalyze new conversations, create connections across and between communities that can facilitate this co-design, and advance progress in the building of more equitable foundations for opening knowledge—discussions and actions that need to be continued, year in and year out. MDPI has always aimed to provide professional and efficient publishing services to scholars around the world.

Our mission is to make scientific research accessible to everyone; this year, we interview and hold discussions with open science ambassadors on how to build an equal and inclusive environment for open science. Academic editors help us collaborate with more institutions to advocate for open access ideas.

Read our anniversary blog post: "Sharing 'Collective Human Knowledge': The Benefits of Open Access Publication"

Besides this, our scientific community is a key driver of our success and MDPI’s remarkable growth. Despite the pandemic, we have prepared online conferences and workshops to gather scholars from different communities.

The Basel Sustainable Publishing online forum provides an equal opportunity for stakeholders and researchers from multi-cultural environments to exchange ideas and eliminate barriers to participation.

Conference date: 25 October 2021, online
Conference website: https://bspf2021.sciforum.net/
Main topics: MDPI discusses the current dilemma of open access science from various perspectives such as governments, libraries, and publishers, and related measures on how to change the status quo of discrimination from a global perspective.

We aim to support equality, inclusion, diversity, and accessibility in scholarly communications. We collaborate with universities and key laboratories and have scholarly communications with researchers, teachers, and students on open access workshops.

• 25 October 2021
  Energies journal and Institute of Mechanics, Chinese Academy of Sciences

• 28 October 2021
  Machines journal and State Key Laboratory of Traction Power, Southwest Jiaotong University

• 29 October 2021
  Processes journal and Beijing Institute of Technology