Composite Hydrogels for Biomedical Applications

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Chemistry and Physics".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 70

Special Issue Editors

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Guest Editor
Department of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria
Interests: drug delivery; hydrogels; controlled delivery; nanoparticles; lipid based drug delivery systems

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Guest Editor
"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania
Interests: amphiphilic cationic polysaccharides; micro- and nanoparticles; natural and synthetic polymers-based hydrogels; composite materials; drug delivery systems

Special Issue Information

Dear Colleagues,

Hydrogels have gained significant scientific attention in tissue engineering and drug delivery processes due to their unique properties. They possess a three-dimensional cross-linked network and the ability to swell in an aqueous medium or physiological fluids. Hydrogels appear to be suitable drug delivery platforms due to their biocompatibility and adaptability. The adequate choice of polymer governs the structure and properties of the hydrogel and can thus provide stimuli responsiveness, tailoring the drug release profiles. Composite hydrogels refer to systems prepared either by a mixture of polymers or hydrogels embedding different nanocarriers. The incorporation of nanocarriers within the hydrogels offers limitless opportunities for the improvement of desired characteristics. The nanoparticles offer a number of advantageous properties, such as a high drug loading, the improvement of bioavailability for drugs with limited aqueous solubility, better targeting and cell internalization, providing stability for problematic substances, etc. Due to their versatile and tunable properties, the composite hydrogels offer the necessary conditions for potential biomedical applications, including drug administration via various routes (oral, dermal, parenteral, ocular, etc.) or other medical disorders (wound healing, chemotherapeutics, tissue engineering, etc.). Nevertheless, we lack thorough understandings of the mechanisms, interactions, and applicability of such composite hydrogel-based drug delivery systems.

Therefore, this Special Issue aims at collecting the most recent scientific progress in the development of composite hydrogels. Original research articles, comprehensive reviews, short communications, and perspectives, with topics addressing—but not limited to—the key findings and contributions on composite hydrogels, including preparation methods, characterization (in vitro and in vivo), and biomedical applications, are welcomed.

Dr. Marta Slavkova
Dr. Marieta Constantin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • hydrogels
  • drug delivery
  • composite hydrogels
  • gel characterization
  • biomedical application
  • wound healing
  • tissue engineering

Published Papers

This special issue is now open for submission.
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