Special Issue "Basic and Translational Research in Inflammatory Bowel Disease"
Deadline for manuscript submissions: closed (30 July 2023) | Viewed by 4165
Interests: chronic inflammation; microbiome; genomics; metabolomics; nutrition
Special Issues, Collections and Topics in MDPI journals
Inflammatory bowel disease (IBD) is a heterogenous chronic inflammatory disease of unknown etiology afflicting large and small intestines. There has been significant progress in understanding IBD’s pathogenesis and the various mechanisms involved in it. IBD is largely classified into Crohn’s disease and ulcerative colitis.
The complex disease mechanisms of IBD appear to be influenced by gene–environment interactions. Large-scale, exploratory “omics” studies have significantly contributed to unraveling these complex mechanisms. Genome-wide association studies provided an early breakthrough in identifying defects in innate immune genes as one of the disease mechanisms. This was followed by various studies on systemic and intestinal immune responses, population genetics, gut microbiota, and environmental factors that greatly helped to improve the knowledge in this area. Exploratory studies are critical to finding novel disease mechanisms, and targeted studies are needed to confirm those mechanisms and provide deeper insights.
There are many remaining gaps in our understanding of IBD that ought to be addressed by basic research studies to identify the causative factors; furthermore, translational studies should be designed to overcome those. This Special Issue invites the submission of both basic and translational research studies involving animal models and human subjects contributing to this field of research.
Dr. Pugazhendhi Srinivasan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gastroenterology Insights is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- inflammatory bowel disease
- intestinal immunity
- gut microbiome