Bioactive Molecules and Health-Promoting Properties in Traditional and Innovative Food and Beverage

A topical collection in Foods (ISSN 2304-8158). This collection belongs to the section "Food Nutrition".

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Editor

Topical Collection Information

Dear Colleagues,

The interest in bioactive molecules, phytochemicals, and health-promoting properties in functional foods continues to grow, powered by increasing research into identifying natural active substances and properties in food and beverage and coupled with consumer demand and public interest. In particular, the primary healthcare needs of the local population in many countries are based on traditional food and beverage derived from natural resources. Traditional food may be important in meeting the high demand in many countries for cost-effective, safe, and natural health-promoting food and beverage to be produced by agri-food industries and used by the local population.

Innovative chromatographic approaches (HPLC fingerprinting, mass spectrometry, and spectrophotometric techniques coupled to chemometrics) may allow the identification and characterization of raw material or commercial final products; moreover, other analytical strategies (e.g., NMR, IR, fluorescence) are necessary to better isolate, characterize, identify, and quantify the effective value of biomolecules included in food applications. Chromatographic and spectrophotometric techniques applied in food chemistry may promote food quality, contributing to sustainable development and a commercial valorization of traditional food and beverage based on natural local resources.

This Topical Collection will collect recent high-quality research and review papers in the field of i) potential health-promoting natural resources and relative derived-food products, such as traditional food and beverage; ii) evaluation of their potential sensory and physico-chemical properties; and iii) phytochemical characterization of the main bioactive compounds, in order to develop innovative health-promoting products or improve traditional food applications with a high health value.

Topics covered in this Topical Collection will include but be not limited to:

  • Traditional foods and their sensory and health-promoting properties;
  • Agrobiodiversity and human nutrition;
  • Food products derived from natural resources;
  • Analytical strategies for bioactive compound identification and quantification;
  • Delivery systems for phytochemicals in foods;
  • Traditional and advanced extraction methods;
  • In vivo and in vitro bioactivity of extracted nutraceuticals.

Dr. Dario Donno
Collection Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • traditional food
  • healthy properties
  • phytochemicals
  • analytical strategies
  • functional foods
  • biological activity tests
  • natural antioxidants

Published Papers (3 papers)

2023

Jump to: 2021

18 pages, 3342 KiB  
Article
Time Domain NMR Approach in the Chemical and Physical Characterization of Hazelnuts (Corylus avellana L.)
by Raffaella Gianferri, Fabio Sciubba, Alessandra Durazzo, Paolo Gabrielli, Ginevra Lombardi-Boccia, Francesca Giorgi, Antonello Santini, Petra Engel, Maria Enrica Di Cocco, Maurizio Delfini and Massimo Lucarini
Foods 2023, 12(10), 1950; https://doi.org/10.3390/foods12101950 - 11 May 2023
Viewed by 1542
Abstract
‘Tonda Gentile Romana’ and ‘Tonda di Giffoni’ (Corylus avellana L.) are two Italian hazelnut cultivars, recognized under the quality labels “Protected Designation of Origin” (PDO) and “Protected Geographical Indication” (PGI), respectively. Hazelnut seeds are characterized by a complex microstructure and the presence [...] Read more.
‘Tonda Gentile Romana’ and ‘Tonda di Giffoni’ (Corylus avellana L.) are two Italian hazelnut cultivars, recognized under the quality labels “Protected Designation of Origin” (PDO) and “Protected Geographical Indication” (PGI), respectively. Hazelnut seeds are characterized by a complex microstructure and the presence of different physical compartments. This peculiarity has been studied and evidenced by Time Domain (TD) Nuclear Magnetic Resonance (NMR) experiments. This technique allowed the assessment of the presence of different diffusion compartments, or domains, by evaluating the distribution of the spin–spin relaxation time (T2).The aim of this research was to develop a method based on 1H NMR relaxometry to study the mobility in fresh hazelnut seeds (‘Tonda di Giffoni’ and ‘Tonda Gentile Romana’), in order to determine differences in seed structure and matrix mobility between the two cultivars. TD-NMR measurements were performed from 8 to 55 °C in order to mimic post-harvest processing as well the microscopic textural properties of hazelnut. The Carr–Purcell–Meiboom–Gill (CPMG) experiments showed five components for ‘Tonda Gentile Romana’ and four components for ‘Tonda di Giffoni’ relaxation times. The two slowest components of relaxation (T2,a about 30–40% of the NMR signal, and T2,b about 50% of the NMR signal) were attributed to the protons of the lipid molecules organized in the organelles (oleosomes), both for the ‘Tonda Gentile Romana’ and for the ‘Tonda di Giffoni’ samples. The component of relaxation T2,c was assigned to cytoplasmic water molecules, and showed a T2 value dominated by diffusive exchange with a reduced value compared to that of pure water at the same temperature. This can be attributed to the water molecules affected by the relaxation effect of the cell walls. The experiments carried out as a function of temperature showed, for ‘Tonda Gentile Romana’, an unexpected trend between 30 and 45 °C, indicating a phase transition in its oil component. This study provides information that could be used to strengthen the specifications underlying the definitions of “Protected Designation of Origin” (PDO) and “Protected Geographical Indication” (PGI). Full article
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2021

Jump to: 2023

23 pages, 3002 KiB  
Article
Multi-Mechanistic In Vitro Evaluation of Antihyperglycemic, Antioxidant and Antiglycation Activities of Three Phenolic-Rich Indian Red Rice Genotypes and In Silico Evaluation of Their Phenolic Metabolites
by Ashrita C. Haldipur and Nagarajan Srividya
Foods 2021, 10(11), 2818; https://doi.org/10.3390/foods10112818 - 16 Nov 2021
Cited by 4 | Viewed by 2594
Abstract
The study evaluated the antidiabetic potential of three traditional Indian red rice genotypes/RR (Kattuyanam/KA, Chennangi/CH & Karungkuruvai/KU) using a combination of in vitro, metabolomics (Quadrupole-Time of Flight-Liquid chromatography-Mass spectrometry/Q-TOF-LC-MS/MS), and in silico techniques. In terms of antihyperglycemic potential, KA exhibited the highest [...] Read more.
The study evaluated the antidiabetic potential of three traditional Indian red rice genotypes/RR (Kattuyanam/KA, Chennangi/CH & Karungkuruvai/KU) using a combination of in vitro, metabolomics (Quadrupole-Time of Flight-Liquid chromatography-Mass spectrometry/Q-TOF-LC-MS/MS), and in silico techniques. In terms of antihyperglycemic potential, KA exhibited the highest inhibitory activity against α-amylase; CH against α-glucosidase; and KU against DPPIV and PTP1B enzymes. KA exhibited the highest antioxidant activity (DPPH, FRAP, and ABTS) and greater inhibition of protein glycation compared to other RR indicating its potential to mitigate diabetic complications. The metabolomic analysis confirmed the presence of 99 phenolics in the sample extracts (KU-71, KA-70, CH-68). Molecular docking studies revealed seven metabolites to be good inhibitors of the four target enzymes and activators of insulin receptor substrate/IRS. The antihyperglycemic and oxidation-glycation reduction composite index revealed KA to have the highest overall antidiabetic potential. Hence, the RR could be utilized in functional foods with a multi-barrelled strategy for diabetes prevention/management. Full article
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22 pages, 2439 KiB  
Article
Phytochemical Composition, Antibacterial Activity, and Antioxidant Properties of the Artocarpus altilis Fruits to Promote Their Consumption in the Comoros Islands as Potential Health-Promoting Food or a Source of Bioactive Molecules for the Food Industry
by Toilibou Soifoini, Dario Donno, Victor Jeannoda, Danielle Doll Rakoto, Ahmed Msahazi, Saidi Mohamed Mkandzile Farhat, Mouandhoime Zahahe Oulam and Gabriele Loris Beccaro
Foods 2021, 10(9), 2136; https://doi.org/10.3390/foods10092136 - 09 Sep 2021
Cited by 9 | Viewed by 5322
Abstract
The present study aimed to evaluate the health-promoting potential of breadfruit (Artocarpus altilis (Parkinson) Fosberg, Moraceae family), a traditional Comorian food, considering the sample variability according to geographic localisation. Moreover, the main aims of this research were also to promote its consumption [...] Read more.
The present study aimed to evaluate the health-promoting potential of breadfruit (Artocarpus altilis (Parkinson) Fosberg, Moraceae family), a traditional Comorian food, considering the sample variability according to geographic localisation. Moreover, the main aims of this research were also to promote its consumption in the Comoros Islands as potential health-promoting food and evaluate it as a source of bioactive molecules for the food industry thanks to its antioxidant and antibacterial properties. Investigations on biologically active substances were carried out on the extracts obtained from breadfruit flours from five regions of Grande Comore (Ngazidja), the main island in Comoros. Phytochemical screening revealed the presence of tannins and polyphenols, flavonoids, leucoanthocyanins, steroids, and triterpenes. The considered secondary metabolites were phenolic compounds, vitamin C, monoterpenes, and organic acids. The contents of total phenolic compounds (mgGAE/100 g of dry weight—DW) in the extracts ranged from 29.69 ± 1.40 (breadfruit from Mbadjini—ExMBA) to 96.14 ± 2.07 (breadfruit from Itsandra—ExITS). These compounds included flavanols, flavonols, cinnamic acid and benzoic acid derivatives, and tannins which were detected at different levels in the different extracts. Chlorogenic acid presented the highest levels between 26.57 ± 0.31 mg/100 g DW (ExMIT) and 43.80 ± 5.43 mg/100 g DW (ExMBA). Quercetin was by far the most quantitatively important flavonol with levels ranging from 14.68 ± 0.19 mg/100 g DW (ExMIT) to 29.60 ± 0.28 mg/100 g DW (ExITS). The extracts were also rich in organic acids and monoterpenes. Quinic acid with contents ranging from 77.25 ± 6.04 mg/100 g DW (ExMBA) to 658.56 ± 0.25 mg/100 g DW of ExHAM was the most important organic acid in all the breadfruit extracts, while limonene was quantitatively the main monoterpene with contents between 85.86 ± 0.23 mg/100 g DW (ExMIT) and 565.45 ± 0.24 mg/100 g DW (ExITS). The antibacterial activity of the extracts was evaluated on twelve pathogens including six Gram (+) bacteria and six Gram (−) bacteria. By the solid medium disc method, except for Escherichia coli and Pseudomonas aeruginosa, all the bacteria were sensitive to one or more extracts. Inhibitory Halo Diameters (IHDs) ranged from 8 mm to 16 mm. Salmonella enterica, Clostridium perfringens, and Vibrio fischeri were the most sensitive with IHD > 14 mm for ExITS. By the liquid microdilution method, MICs ranged from 3.12 mg/mL to 50 mg/mL and varied depending on the extract. Bacillus megaterium was the most sensitive with MICs ≤ 12.5 mg/mL. Pseudomonas aeruginosa, Shigella flexneri, and Vibrio fischeri were the least sensitive with all MICs ≥ 12.5 mg/mL. ExHAM was most effective with a MIC of 3.12 mg/mL on Staphylococcus aureus and 6.25 mg/mL on Salmonella enterica. The antioxidant power of the extracts was evaluated by the FRAP method. The activity ranged from 5.44 ± 0.35 (ExMBA) to 14.83 ± 0.11 mmol Fe2+/kg DW (ExHAM). Breadfruit from different regions of Comoros contained different classes of secondary metabolites well known for their important pharmacological properties. The results of this study on phenolics, monoterpenes, and organic acids have provided new data on these fruits. The obtained results showed that breadfruit from the biggest island of the Union of Comoros also presented antimicrobial and antioxidant properties, even if some differences in effectiveness existed between fruits from different regions. Full article
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