Recent Advances in Syngas Fermentation

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Industrial Fermentation".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 1541

Special Issue Editor

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Guest Editor
Department of Chemical and Biological Engineering, Catalysis and Chemical reaction Engineering Laboratory, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK S7N5A9, Canada
Interests: biomass; biofuels; fermentation; hydrogen; anaerobic digestion; process simulation; machine learning; bioethanol; gasification; hydrothermal flames; carbon capture

Special Issue Information

Dear Colleagues,

The issues of climate change, increasing world population, and energy demand have encouraged research in alternative energy resources over the past few years. Thermochemical (e.g., pyrolysis and gasification) and biological processes (e.g., anaerobic digestion and syngas fermentation) are promising valorization technologies for converting biogenic waste into sustainable fuels and green chemicals. Syngas fermentation is advantageous because it does not require biomass pretreatment. In addition, it is a promising alternative to Fischer–Tropsch Synthesis (FT) for the production of liquid fuels. It has been studied up to an industrial scale over the past few years. Compared to FT, syngas fermentation does not require a fixed CO/H2 ratio. Several studies have been performed to overcome the limitations of syngas fermentation, including poor mass transfer issues, low gas solubility and low productivity.

This Special Issue aims to publish both recent innovative research results and review articles on syngas fermentation. This includes but is not limited to experimental studies related to syngas fermentation to alcohols, integration of gasification with syngas fermentation for biofuel production, process modelling, techno-economic analysis and life cycle assessment of syngas fermentation integrated with other biomass conversion processes, harnessing the power of machine learning for syngas fermentation. In addition, we welcome submissions from authors working on syngas fermentation process optimization, reactor design, computational fluid dynamics applied to syngas fermentation and microbiological catalysts for syngas fermentation.

If you would like to contribute a review paper, please get in touch with one of the editors to discuss the topic’s relevance before submitting the manuscript.

Dr. Jude Okolie
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • syngas fermentation
  • anaerobic digestion
  • gasification
  • biogas
  • alcohols
  • biofuels
  • techno-economic analysis
  • lifecycle assessment
  • biomass
  • process simulation
  • machine learning

Published Papers (1 paper)

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17 pages, 3408 KiB  
Acetate Production by Moorella thermoacetica via Syngas Fermentation: Effect of Yeast Extract and Syngas Composition
by Budi Mandra Harahap and Birgitte K. Ahring
Fermentation 2023, 9(9), 826; - 9 Sep 2023
Viewed by 1235
Gasifiers produce a gaseous mixture of CO/CO2/H2, also known as synthesis gas (syngas), containing varying compositions and ratios depending on the lignocellulose material types, gasifier design, and gasification conditions. Different physicochemical and thermodynamic properties of each gas type in [...] Read more.
Gasifiers produce a gaseous mixture of CO/CO2/H2, also known as synthesis gas (syngas), containing varying compositions and ratios depending on the lignocellulose material types, gasifier design, and gasification conditions. Different physicochemical and thermodynamic properties of each gas type in the various syngas blends can influence syngas fermentation performance for the production of chemicals such as acetate. This study examined the effect of syngas composition (CO, CO/H2, CO/CO2/H2, and CO/H2) and its corresponding ratio on acetate production using Moorella thermoacetica, a thermophilic homoacetogen as the biocatalyst. We also investigated the effect of yeast extract addition for enhancing acetate production. A syngas fermentation study performed at a total pressure of 19 psig (2.29 atm) demonstrated that syngas fermentation in the absence of CO (30%CO2/70%H2) or at low CO proportions (21%CO/24%CO2/55%H2) resulted in the highest volumetric productivity of acetate (0.046 ± 0.001 and 0.037 ± 0.001 g/L/h, respectively). Interestingly, syngas fermentation without CO reached the highest YP/X of 22.461 ± 0.574 g-acetate/g-biomass, indicating that more acetate was produced compared to cell biomass. Higher biomass production was obtained when the CO proportion was increased up to 75% in CO/H2 fermentation. However, the cell growth and acetate production dramatically decreased with increasing CO proportion up to 99.5% CO as the sole constituent of the syngas. Even so, acetate production using 99.5% CO could be improved by adding 2 g/L yeast extract. Full article
(This article belongs to the Special Issue Recent Advances in Syngas Fermentation)
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