Special Issue "Recent Trends in High-Cell-Density Fermentation Strategies for Microbial Lipids"
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 1130
Interests: molecular mechanisms of lipid biosynthesis; biochemistry; microbial lipids; M. circinelloides; genetic engineering; fatty acids synthesis; biomass and value-added products; chemical engineering; fermentation biotechnology; food chemistry; functional foods; applied microbiology; natural products
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Recently, there has been considerable concern over the traditional fermentation process and nutritional problems accompanying the rapid growth of the world population and the current economic situation. Thus, it is necessary to find an effective and suitable fermentation process for lipid production. Oleaginous microorganisms, including fungi, yeasts, algae, bacteria, etc., are widely used in the fermentation industry, and they have been considered powerful oil sources for lipid and biodiesel production based on their ability to accumulate large amounts of lipids. The major challenges in fermentation production systems are low reaction rates and high capital costs. High-cell-density culture is an effective method to enhance the volumetric productivity of the fermentation process, thus making the process faster and more robust. High levels of cell biomass in defined media can be easily achieved; therefore, large quantities of recombinant products with enhanced activities at lower cost can be obtained through high-cell-density fermentation technology. The development of microbial strains and their fermentation process has been implemented to produce significant lipids and multiple significant fatty acids with nutritional importance.
However, to develop efficient fermentation technologies for biomass, lipid, and biofuel production, more significant research attention needs to be directed toward biotechnological and genetic improvement of the potential organisms utilized in the process by using useful, varied fermentation strategies.
In this Special Issue, we will cover some recent progress focused on novel fermentation methods, molecular techniques, and the development of additional microbial models for varied biotechnological applications and their ability to modulate, regulate, and maximize production through high-cell-density fermentation strategies. We aim to (a) provide an introductory overview of microbial lipids and to show the current attention being paid to their production and the use of oleaginous microorganisms as powerful sources of oils and fats, (b) high-throughput screening technologies for industrially important lipids and fatty-acid-producing microorganisms under special fermentation models, (c) highlight novel fermentation methods and trends proposed to produce high biomass and lipids and lipid derivatives in sufficient quantities by targeting microorganisms, (d) provide an overview of discovered model species and their fermentation approaches, and (e) give insights into the molecular mechanisms of stress response and tolerance during various fermentation strategies.
Prof. Dr. Yuanda Song
Dr. Wanwipa Vongsangnak
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- oleaginous microorganisms
- microbial lipids
- lipid biosynthesis
- fed-batch fermentation
- batch fermentation
- genetic manipulation
- lipid biochemistry
- fatty acids
- lipid accumulation