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Special Issue "Thoracic Aortic Disease: From Bench to Bedside"
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 12298
Special Issue Editors
Interests: valvular heart disease; diseases of the aorta; hypertrophic cardiomyopathy; diastolic function; definition of normalcy; primary care cardiology; preclinical left ventricular dysfunction; chronic heart failure; echocardiography; guidelines implementation
Interests: cardiovascular diseases; atherothrombotic diseases; clinical pathology; molecular biology; genetics; pharmacogenetics; diagnosis; omics approaches; genetic bases of cardiovascular diseases; pathophysiology of cardiovascular diseases
E-Mail Website1 Website2
Interests: hereditary thoracic aortic aneurysms and dissections; inherited connective tissue disorders; congenital heart diseases; molecular mechanisms underlying hereditary diseases; genotype-phenotype correlation; clinical, biochemical and genetic biomarkers; early diagnosis comorbidities; guidelines implementation
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Special Issue Information
The thoracic aorta is a complex structure that can be involved in a variety of pathological processes, resulting in a wide spectrum of either acute or chronic disorders. Aneurysm of the thoracic aorta is the most common of these disorders, and is commonly encountered in outpatient, non-referral settings. The clinical cardiologist is thus called to a substantial number of actions aimed not only at proper anatomical definition and quantitation, but, even more importantly, at accurately defining the etiology and pathogenesis of the aortic aneurysm in an individual patient. Such a complex diagnostic work-out relies on simple medical actions (e.g., family history-taking), but also on the integration of refined imaging modalities and clinico-genetic evaluations.
This Special Issue is thus aimed at providing clinical cardiologists, but also internists and general practitioners (usually the first to encounter patients with thoracic aortic aneurysms) with a summary of updated evidence to support an appropriate referral pattern. We will examine multiple etiologies, their biomolecular and pathogenetic backgrounds, the utilization of different imaging modalities, their integration in a multimodal approach, as well as precise clinical approaches for timely follow-up strategies—including medical therapies and address to interventions. Moreover, problems related to the definition of normalcy/abnormalcy, and the potential implications for physical activities and sport, should be considered. Similarly, the strategies to be utilized in patients after an acute thoracic aortic syndrome will be analyzed, together with the needs of their relatives for clinical and genetic screenings.
The unique profile of this Special Issue will be constituted by its main aim: to provide clinicians practicing in primary care or non-referral settings with updated knowledge on diseases of the thoracic aorta by experts in the multiple fields involved in research and assistance of these relatively common patients.
Dr. Stefano Nistri
Prof. Dr. Betti Giusti
Prof. Dr. Guglielmina Pepe
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- aorta, thoracic
- aortic aneurysm
- aortic dissection
- aortic ulcer
- aortic wall
- bicuspid aortic valve
- cardiac surgical indications
- computed tomography
- coronary angiography
- diagnostic imaging
- exome sequencing
- aortic aneurysm
- first-degree relatives
- growth/dilation rate
- intramural hematoma
- linkage analysis
- magnetic resonance
- natural history
- next-generation sequencing
- non-syndromic aortic aneurysm/dissecting
- screening aortic aneurysm
- sporadic thoracic aorta
- syndromic aortic aneurysm
- trans-thoracic, transesophageal
- whole exome
- whole genome