Special Issue "Lab-on-a-Chip Based Diagnostics"
Deadline for manuscript submissions: closed (31 July 2017) | Viewed by 17259
Interests: immunoassays; IVD; POC technologies; molecular diagnostics; next-generation sequencing; mobile healthcare
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Lab-on-a-chip technologies have led to remarkable advances in diagnostics in recent years. These advances include the development of a wide range of diagnostic platforms; novel microfluidic operations; the development of fully-integrated and automated bioanalytical platforms and systems; strategies for multiplex detection; prolonged storage of assay reagents and biomolecules; incorporation of various biosensing principles; rapid and highly-simplified assay formats; surface modification and leach-proof biomolecular immobilization schemes; strategies for reducing non-specific binding; signal enhancement procedures; cost-effective prototyping and mass-production of LOC platforms; smartphone-based readout of LOC assays; and, assay formats and devices enabling mobile healthcare and point-of-care testing (POCT). These developments have led to prospective LOC-based diagnostics that enable fully integrated and automated analysis of analytes at decentralized, remote, and POC settings apart from central laboratories. New biorecognition elements, such as aptamers, are further enabling the development of highly-sensitive assays. Similarly, paper-based assays, such as lateral flow assays, are rapid and low-cost diagnostic platforms for potential applications in developing nations. A plethora of smartphone-based POC devices, such as the integrated rapid test strip reader and smartphone-based LOC device for multiplex detection, are further paving the way for critically improved diagnostics at POC settings. The coming years will witness many such LOC technologies making their way into the commercial market. The continuous increase in the market share and penetration of such technologies will fuel the development of next-generation of LOC-based personalized mobile healthcare devices.
Dr. Sandeep K. Vashist
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Lab-on-a-chip based diagnostics
- Lab-on-a-chip platforms
- Molecular Diagnostics
- Multiplex detection
- Integrated systems
- Aptamer-based assays
- Lateral flow assays
- Electrochemical biosensors
- Signal enhancement
- Label-free assays
- Magnetic bead-based assays
- Paper-based assays
- Smartphone-based analysis
- Point-of-care analysis
- Wireless monitoring
- Mobile healthcare