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Special Issue "Detection and Assessment of SARS-CoV-2 Variants"
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Diagnostic Microbiology and Infectious Disease".
Deadline for manuscript submissions: 31 August 2023 | Viewed by 3781
Special Issue Editor
Interests: clinical pathology; molecular diagnosis; genome; epidemiology
Special Issue Information
Since the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Alpha was identified in England in late November 2021, mutations in the viral genome can increase transmissibility, facilitate escape from the human immune system, and/or alter biologically important phenotypes. The SARS-CoV-2 variants are classified as variants being monitored (VBMs), variants of interest (VOIs), variants of concern (VOCs), and variants of high consequence (VOHCs). There are two currently circulating SARS-CoV-2 VOCs (Delta and Omicron), and three previously circulating VOCs (Alpha, Beta, and Gamma) in a way that confers a fitness advantage to the virus, such as mutations in the spike (S) gene that affect antigenicity. Each characterized variant has mutations in the gene encoding the S protein (Omicron: 30 mutations; Delta: 10 mutations; Alpha: 7 mutations and 2 deletions; Beta: 9 mutations and 1 deletion; and Gamma: >10 mutations), compared to the sequence of the wild type index virus (Wuhan-Hu-1).
Previous studies have pointed out that viral genomic mutations leading to new variants of SARS-CoV-2 are a real challenge in tackling the global coronavirus disease (COVID-19). Understanding SARS-CoV-2 variants remains an issue of concern for all local government authorities and are critical for establishing and implementing effective public health measures.
This Special Issue on “Detection and Assessment of SARS-CoV-2 Variants” will cover all related areas, such as diagnostic applications, VOC pathogen detection, biomarker monitoring, and others of concern.
Prof. Dr. Hung-Sheng Shang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- variant of concerns
- pathogen detection