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Special Issue "Current Issue and Perspectives in Dermatopathology"

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A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 May 2023 | Viewed by 3090

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Special Issue Editors

Dr. Gerardo Cazzato

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Guest Editor

Section of Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy
Interests: dermatopathology, dermatology; skin diseases; skin tumors; soft tissue pathology; gynecopathology; neuropathology
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Dr. Caterina Foti

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Guest Editor

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Bari, Italy
Interests: dermatopathology; dermatology; skin diseases; skin tumors; soft tissue pathology; gynecopathology; neuropathology

Special Issue Information

Dear Colleagues,

Dermatopathological diagnostics embraces a large amount of information, as pathologies of different natures can occur at the skin level: inflammatory, immune, and accumulation pathologies, histiocytosis, and neoplastic pathologies proper. Although molecular biology is promising as a tool, dermatopathological diagnostics is still fully based on morphology and ancillary immunohistochemical techniques. In this Special Issue, we aim to collect case reports, case series, editorials, letters to the editor, original articles, and reviews that can help pathologists in daily diagnostics as well as provide a basis on which to start new insights and discoveries.

Dr. Gerardo Cazzato
Dr. Caterina Foti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

dermatopathology
soft-tissue pathology
non-melanoma skin cancer
malignant melanoma

Published Papers (4 papers)

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Open AccessInteresting Images

Cutaneous Sarcoidosis-like Eruption Following Second Dose of Moderna mRNA-1273 Vaccine: Case or Relationship?

Gerardo Cazzato

Francesca Ambrogio

Caterina Foti

Marialessandra Capuzzolo

and

Diagnostics 2023, 13(7), 1286; https://doi.org/10.3390/diagnostics13071286 - 29 Mar 2023

Cited by 1 | Viewed by 927

Abstract

Various adverse reactions to SARS-CoV-2 vaccines have been described since the first months of the vaccination campaign. In addition to more frequent reactions, rare reactions, such as sarcoidosis-like, rashes have been reported. We present a case of a 23-year-old woman with a rash on the chin and peribuccal region, which developed approximately 3 weeks after the administration of the second dose of the Moderna mRNA-1273 vaccine. We briefly discuss other reports in the literature. Full article

(This article belongs to the Special Issue Current Issue and Perspectives in Dermatopathology)

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Photodynamic Therapy Used to Treat an HIV Patient with an Efflorescence of Viral Warts after HAART Therapy

Francesca Ambrogio

Alexandre Raphael Meduri

and

Diagnostics 2023, 13(6), 1098; https://doi.org/10.3390/diagnostics13061098 - 14 Mar 2023

Viewed by 483

Abstract

Healing from viral warts lesions can be hard to achieve in immunocompromised subjects like HIV-positive patients. The therapeutic target in immunocompetent subjects can be reached using different methods, including topical ointments, cryotherapy, laser therapy, imiquimod, and photodynamic therapy (PDT). We present a case of a male HIV-positive patient who came to the Dermatology department with multifocal wart lesions on his face, auricular, and retro-auricular areas after treatment with highly active antiretroviral therapy (HAART). In our case, surprisingly, only one session of PDT proved to induce complete regression of lesions which, despite their thickness, had a much more robust response to treatment than we could have possibly expected. After a brief review of the literature, it is possible to state that PDT revealed itself to be a valid option in immunocompromised patients who have a major risk of relapse. Full article

(This article belongs to the Special Issue Current Issue and Perspectives in Dermatopathology)

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Photography as the Sole Means of Proof: Medical Liability in Dermatology

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Diagnostics 2023, 13(6), 1033; https://doi.org/10.3390/diagnostics13061033 - 08 Mar 2023

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Abstract

Malignant melanoma is a cutaneous malignancy resulting from the uncontrolled proliferation of melanocytes and poses a challenge diagnostically because neoplastic lesions can mimic benign lesions, which are much more common in the population. Doctors, when they suspect the presence of melanoma, arrange for its removal and the performance of a histological examination to ascertain its diagnosis; in cases where the dermatoscopic examination is indicative of benignity, however, after the lesion is removed, histological examination is not always performed, a very dangerous occurrence and a harbinger of further medico-legal problems. The authors present a court litigation case of an “alleged” failure to diagnose malignant melanoma in a patient who died of brain metastases from melanoma in the absence of a certain location of the primary tumor: the physician who had removed a benign lesion a few months earlier was sued, and only thanks to the presence of photographic documentation was the health care provider able to prove his extraneousness. The aim of this paper is to formulate a proposal for a dermatological protocol to be followed in cases of excisions of benign skin lesions with a twofold purpose: on the one hand, to be able to prove, in a judicial context, the right action on the part of the sanitarians; on the other hand, to avoid the rise of so-called “defensive medicine”. Full article

(This article belongs to the Special Issue Current Issue and Perspectives in Dermatopathology)

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Partially Dedifferentiated Primitive Malignant Melanoma with Pseudo-Angiomatous Features: A Case Report with Review of the Literature

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Diagnostics 2023, 13(3), 495; https://doi.org/10.3390/diagnostics13030495 - 29 Jan 2023

Viewed by 825

Abstract

Malignant melanoma (MM) is traditionally known as the “great mime” of human pathology, as it is potentially capable of imitating the most disparate neoplasms. It is known that in addition to the more classic histotypes of MM, there are also rare forms, including angiomatoid MM. Similarly, it has been amply demonstrated in the literature that MM is capable of dedifferentiating, losing melanocytic lineage markers, constituting a diagnostic challenge for the pathologist. Although 5 cases of primary angiomatoid MM have been described in the literature, to the best of our knowledge, no cases of dedifferentiated melanoma with pseudo-angiomatoid aspects have ever been described. In this paper, we present a very rare case of partially dedifferentiated MM in which the most dedifferentiated component lost melanocytic lineage immunohistochemical markers and assumed a pseudo-angiomatous morphology. Given the rarity of the case, we carried out a literature review of similar cases described, trying to draw new future perspectives not only about this particular variant of MM but also about the widest field of dedifferentiation/undifferentiation of MM. Full article

(This article belongs to the Special Issue Current Issue and Perspectives in Dermatopathology)

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Special Issue "Current Issue and Perspectives in Dermatopathology"

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