Artificial Intelligence in Neuroimaging for Diagnosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Machine Learning and Artificial Intelligence in Diagnostics".

Deadline for manuscript submissions: closed (1 September 2023) | Viewed by 6981

Special Issue Editors


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Guest Editor
Technology Faculty, Firat Üniversitesi, Elazig, Türkiye
Interests: deep learning; image processing; signal processing; feature engineering

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Guest Editor
Department of Digital Forensics Engineering, College of Technology, Firat University, Elazig, Turkey
Interests: feature engineering; machine learning; biomedical image and signal processing; pattern recognition; computer forensics; mobile forensics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Imaging technologies have often been used in medicine to diagnose many disorders. However, there are some human errors in diagnosis. The best way to recommend an intelligent assistant for diagnosis is machine learning. Computer vision has improved tremendously, especially after deep learning networks were recommended. In this special issue, we plan to publish papers of models that use neuroimaging techniques and artificial intelligence together. We look forward to publishing your high-quality papers in our journal that present the contributions of the latest technology in computer vision or deep learning methods or the methods you recommend to the field. Moreover, you can submit signal processing-based machine learning models to this special issue.

Dr. Turker Tuncer
Dr. Sengul Dogan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MR image classification
  • facial expression recognition
  • MR image segmentation
  • EEG signal classification
  • sEMG signal classification

Published Papers (3 papers)

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Research

24 pages, 3235 KiB  
Article
Effective Early Detection of Epileptic Seizures through EEG Signals Using Classification Algorithms Based on t-Distributed Stochastic Neighbor Embedding and K-Means
by Khaled M. Alalayah, Ebrahim Mohammed Senan, Hany F. Atlam, Ibrahim Abdulrab Ahmed and Hamzeh Salameh Ahmad Shatnawi
Diagnostics 2023, 13(11), 1957; https://doi.org/10.3390/diagnostics13111957 - 03 Jun 2023
Cited by 4 | Viewed by 2499
Abstract
Epilepsy is a neurological disorder in the activity of brain cells that leads to seizures. An electroencephalogram (EEG) can detect seizures as it contains physiological information of the neural activity of the brain. However, visual examination of EEG by experts is time consuming, [...] Read more.
Epilepsy is a neurological disorder in the activity of brain cells that leads to seizures. An electroencephalogram (EEG) can detect seizures as it contains physiological information of the neural activity of the brain. However, visual examination of EEG by experts is time consuming, and their diagnoses may even contradict each other. Thus, an automated computer-aided diagnosis for EEG diagnostics is necessary. Therefore, this paper proposes an effective approach for the early detection of epilepsy. The proposed approach involves the extraction of important features and classification. First, signal components are decomposed to extract the features via the discrete wavelet transform (DWT) method. Principal component analysis (PCA) and the t-distributed stochastic neighbor embedding (t-SNE) algorithm were applied to reduce the dimensions and focus on the most important features. Subsequently, K-means clustering + PCA and K-means clustering + t-SNE were used to divide the dataset into subgroups to reduce the dimensions and focus on the most important representative features of epilepsy. The features extracted from these steps were fed to extreme gradient boosting, K-nearest neighbors (K-NN), decision tree (DT), random forest (RF) and multilayer perceptron (MLP) classifiers. The experimental results demonstrated that the proposed approach provides superior results to those of existing studies. During the testing phase, the RF classifier with DWT and PCA achieved an accuracy of 97.96%, precision of 99.1%, recall of 94.41% and F1 score of 97.41%. Moreover, the RF classifier with DWT and t-SNE attained an accuracy of 98.09%, precision of 99.1%, recall of 93.9% and F1 score of 96.21%. In comparison, the MLP classifier with PCA + K-means reached an accuracy of 98.98%, precision of 99.16%, recall of 95.69% and F1 score of 97.4%. Full article
(This article belongs to the Special Issue Artificial Intelligence in Neuroimaging for Diagnosis)
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15 pages, 4128 KiB  
Article
Identifying Complex Emotions in Alexithymia Affected Adolescents Using Machine Learning Techniques
by Stephen Dass ArulDass and Prabhu Jayagopal
Diagnostics 2022, 12(12), 3188; https://doi.org/10.3390/diagnostics12123188 - 16 Dec 2022
Cited by 2 | Viewed by 2270
Abstract
Many scientific researchers’ study focuses on enhancing automated systems to identify emotions and thus relies on brain signals. This study focuses on how brain wave signals can be used to classify many emotional states of humans. Electroencephalography (EEG)-based affective computing predominantly focuses on [...] Read more.
Many scientific researchers’ study focuses on enhancing automated systems to identify emotions and thus relies on brain signals. This study focuses on how brain wave signals can be used to classify many emotional states of humans. Electroencephalography (EEG)-based affective computing predominantly focuses on emotion classification based on facial expression, speech recognition, and text-based recognition through multimodality stimuli. The proposed work aims to implement a methodology to identify and codify discrete complex emotions such as pleasure and grief in a rare psychological disorder known as alexithymia. This type of disorder is highly elicited in unstable, fragile countries such as South Sudan, Lebanon, and Mauritius. These countries are continuously affected by civil wars and disaster and politically unstable, leading to a very poor economy and education system. This study focuses on an adolescent age group dataset by recording physiological data when emotion is exhibited in a multimodal virtual environment. We decocted time frequency analysis and amplitude time series correlates including frontal alpha symmetry using a complex Morlet wavelet. For data visualization, we used the UMAP technique to obtain a clear district view of emotions. We performed 5-fold cross validation along with 1 s window subjective classification on the dataset. We opted for traditional machine learning techniques to identify complex emotion labeling. Full article
(This article belongs to the Special Issue Artificial Intelligence in Neuroimaging for Diagnosis)
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13 pages, 1948 KiB  
Article
The Added Value of Intraventricular Hemorrhage on the Radiomics Analysis for the Prediction of Hematoma Expansion of Spontaneous Intracerebral Hemorrhage
by Te-Chang Wu, Yan-Lin Liu, Jeon-Hor Chen, Yang Zhang, Tai-Yuan Chen, Ching-Chung Ko and Min-Ying Su
Diagnostics 2022, 12(11), 2755; https://doi.org/10.3390/diagnostics12112755 - 10 Nov 2022
Cited by 1 | Viewed by 1378
Abstract
Background: Among patients undergoing head computed tomography (CT) scans within 3 h of spontaneous intracerebral hemorrhage (sICH), 28% to 38% have hematoma expansion (HE) on follow-up CT. This study aimed to predict HE using radiomics analysis and investigate the impact of intraventricular hemorrhage [...] Read more.
Background: Among patients undergoing head computed tomography (CT) scans within 3 h of spontaneous intracerebral hemorrhage (sICH), 28% to 38% have hematoma expansion (HE) on follow-up CT. This study aimed to predict HE using radiomics analysis and investigate the impact of intraventricular hemorrhage (IVH) compared with the conventional approach based on intraparenchymal hemorrhage (IPH) alone. Methods: This retrospective study enrolled 127 patients with baseline and follow-up non-contrast CT (NCCT) within 4~72 h of sICH. IPH and IVH were outlined separately for performing radiomics analysis. HE was defined as an absolute hematoma growth > 6 mL or percentage growth > 33% of either IPH (HEP) or a combination of IPH and IVH (HEP+V) at follow-up. Radiomic features were extracted using PyRadiomics, and then the support vector machine (SVM) was used to build the classification model. For each case, a radiomics score was generated to indicate the probability of HE. Results: There were 57 (44.9%) HEP and 70 (55.1%) non-HEP based on IPH alone, and 58 (45.7%) HEP+V and 69 (54.3%) non-HEP+V based on IPH + IVH. The majority (>94%) of HE patients had poor early outcomes (death or modified Rankin Scale > 3 at discharge). The radiomics model built using baseline IPH to predict HEP (RMP) showed 76.4% accuracy and 0.73 area under the ROC curve (AUC). The other model using IPH + IVH to predict HEP+V (RMP+V) had higher accuracy (81.9%) with AUC = 0.80, and this model could predict poor outcomes. The sensitivity/specificity of RMP and RMP+V for HE prediction were 71.9%/80.0% and 79.3%/84.1%, respectively. Conclusion: The proposed radiomics approach with additional IVH information can improve the accuracy in prediction of HE, which is associated with poor clinical outcomes. A reliable radiomics model may provide a robust tool to help manage ICH patients and to enroll high-risk ICH cases into anti-expansion or neuroprotection drug trials. Full article
(This article belongs to the Special Issue Artificial Intelligence in Neuroimaging for Diagnosis)
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