Artificial Intelligence in Cardiovascular Medicine

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Machine Learning and Artificial Intelligence in Diagnostics".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 1018

Special Issue Editor


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Guest Editor
Division of Cardiology, "AOU Città della Salute e della Scienza di Torino" Hospital, Department of Medical Sciences, University of Turin, 10126 Turin, Italy
Interests: atrial fibrillation; clinical cardiology; cardiac arrhythmias; artificial intelligence; modeling and simulation
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Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue on "Artificial Intelligence in Cardiovascular Medicine". This issue aims to explore the latest developments in the use of artificial intelligence (AI) in the field of cardiovascular medicine.

Cardiovascular diseases are a leading cause of death globally, and the use of AI has the potential to improve the diagnosis, treatment, and prevention of these conditions. This Special Issue welcomes original research articles, reviews, and short communications on various aspects of AI in cardiovascular medicine, including but not limited to:

  • AI applications to detect the early signs of cardiovascular diseases through physiological data analysis and biosensors;
  • AI techniques for cardiovascular medical imaging analysis;
  • AI-powered decision support systems for clinicians to aid in diagnosis and personalized treatment plans;
  • The role of AI in precision medicine for cardiovascular disease management, using genetic and other data to optimize individualized treatment;
  • Ethical and legal considerations in the use of AI in cardiovascular medicine.

We look forward to receiving your contributions.

Dr. Andrea Saglietto
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

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Published Papers (1 paper)

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Research

14 pages, 2021 KiB  
Article
Development and Validation of a Predictive Model Based on LASSO Regression: Predicting the Risk of Early Recurrence of Atrial Fibrillation after Radiofrequency Catheter Ablation
by Mengdie Liu, Qianqian Li, Junbao Zhang and Yanjun Chen
Diagnostics 2023, 13(22), 3403; https://doi.org/10.3390/diagnostics13223403 - 08 Nov 2023
Cited by 1 | Viewed by 788
Abstract
Background: Although recurrence rates after radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF) remain high, there are a limited number of novel, high-quality mathematical predictive models that can be used to assess early recurrence after RFCA in patients with AF. Purpose: [...] Read more.
Background: Although recurrence rates after radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF) remain high, there are a limited number of novel, high-quality mathematical predictive models that can be used to assess early recurrence after RFCA in patients with AF. Purpose: To identify the preoperative serum biomarkers and clinical characteristics associated with post-RFCA early recurrence of AF and develop a novel risk model based on least absolute shrinkage and selection operator (LASSO) regression to select important variables for predicting the risk of early recurrence of AF after RFCA. Methods: This study collected a dataset of 136 atrial fibrillation patients who underwent RFCA for the first time at Peking University Shenzhen Hospital from May 2016 to July 2022. The dataset included clinical characteristics, laboratory results, medication treatments, and other relevant parameters. LASSO regression was performed on 100 cycles of data. Variables present in at least one of the 100 cycles were selected to determine factors associated with the early recurrence of AF. Then, multivariable logistic regression analysis was applied to build a prediction model introducing the predictors selected from the LASSO regression analysis. A nomogram model for early post-RFCA recurrence in AF patients was developed based on visual analysis of the selected variables. Internal validation was conducted using the bootstrap method with 100 resamples. The model’s discriminatory ability was determined by calculating the area under the curve (AUC), and calibration analysis and decision curve analysis (DCA) were performed on the model. Results: In a 3-month follow-up of AF patients (n = 136) who underwent RFCA, there were 47 recurrences of and 89 non-recurrences of AF after RFCA. P, PLR, RDW, LDL, and CRI-II were associated with early recurrence of AF after RFCA in patients with AF (p < 0.05). We developed a predictive model using LASSO regression, incorporating four robust factors (PLR, RDW, LDL, CRI-II). The AUC of this prediction model was 0.7248 (95% CI 0.6342–0.8155), and the AUC of the internal validation using the bootstrap method was 0.8403 (95% CI 0.7684–0.9122). The model demonstrated a strong predictive capability, along with favorable calibration and clinical applicability. The Hosmer–Lemeshow test indicated that there was good consistency between the predicted and observed values. Additionally, DCA highlighted the model’s advantages in terms of its clinical application. Conclusions: We have developed and validated a risk prediction model for the early recurrence of AF after RFCA, demonstrating strong clinical applicability and diagnostic performance. This model plays a crucial role in guiding physicians in preoperative assessment and clinical decision-making. This novel approach also provides physicians with personalized management recommendations. Full article
(This article belongs to the Special Issue Artificial Intelligence in Cardiovascular Medicine)
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