Topical Collection "Chirality in Drugs and Drug Candidates"
2. Centro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), Universidade do Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4050-208 Matosinhos, Portugal
Interests: medicinal chemistry; organic chemistry; chiral bioactive substances; enantioselective studies; chirality; chromatography
Special Issues, Collections and Topics in MDPI journals
Special Issue in Molecules: Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition
Special Issue in Molecules: Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition II
Special Issue in Molecules: Chiral Psychoactive Substances: Identification, Toxicity, and Enantioselective Studies
Special Issue in Marine Drugs: Marine Antiparasitic Agents
2. Laboratory of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: medicinal chemistry; organic synthesis; heterocycles; P-glycoprotein; anticancer; antimicrobials; chiral drugs; marine natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue in Pharmaceuticals: Grand Celebration: 100th Anniversary of the Discovery of Heparin
Special Issue in Pharmaceuticals: Selected papers from the 11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry in Portugal
Special Issue in Molecules: Can Membrane Transporters Contribute to Drug Discovery?
Special Issue in Marine Drugs: Marine Products for Health and Beauty
Special Issue in Molecules: Xanthones: Themed Issue in Honor of Professor Madalena Pinto on the Occasion of Her 70th Birthday
Special Issue in Pharmaceuticals: The Story of Successful Drugs and Recent FDA-Approved Molecules
Special Issue in Molecules: Nature-Inspired Antitumor Agents
Special Issue in Molecules: Recent Contributions of Female Scientists to the Advancement of Medicinal Chemistry
Special Issue in Molecules: Molecules Medicinal Chemistry Reviews
Special Issue in Pharmaceuticals: Advances in Pharmaceutical Sciences: In Honor of Dr. Jean Jacques Vanden Eynde (JJ)
Special Issue in Pharmaceuticals: Selected Papers from the 8th International Electronic Conference on Medicinal Chemistry (ECMC2022)
Special Issue in Pharmaceuticals: Selected Papers from the 9th International Electronic Conference on Medicinal Chemistry (ECMC2023)
Over the last several years, the relationship between chirality and therapeutic activities has been of increasing importance in the drug discovery pipeline. Chirality is ubiquitous in biological systems, and can therefore have a key influence on drug pharmacodynamics, pharmacokinetics, and toxicity. Chirality can now be considered one of the major topics in the design, discovery, synthesis, development, evaluation, and marketing of new drugs, both for human and veterinary use. In addition to the increase of chiral drugs in the market, the relevance of enantioselective studies boosts each year due to advantages in potency, efficacy, selectivity, and safety associated with the use of single enantiomers. The advances in enantioselective synthesis as well as enantioseparation methodologies aligned to the stricter requirements from regulatory authorities to patent new chiral drugs led to increased research in this field.
This Topical Collection invites critical reviews, original research articles and other formats with comprehensive theoretical and experimental details focused on all aspects of chirality involved in drugs and drug candidates. This Topical Collection has the broad goal of illustrating recent and future trends in the development of successful chiral drugs and the search for new promising chiral drug candidates. Topics include the discovery, design and development of new chiral leads as well as synthetic and natural chiral drugs; chiral recognition studies; enantioselective synthesis; enantiomeric resolution; chiral drug analysis; stereochemical elucidation; and enantioselective studies on drug and drug candidate pharmacodynamics, pharmacokinetics, toxicity, and environment.
Dr. Maria Emília De Sousa
Dr. Carla Fernandes
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Drugs and Drug Candidates is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- synthetic and natural chiral drugs
- novel chiral drug candidates
- chiral recognition
- enantioselective synthesis
- chiral analysis
- enantioselective studies