Evaluating and Improving Outcomes of Gastric Cancer Surgery

A special issue of Current Oncology (ISSN 1718-7729).

Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 2491

Special Issue Editors


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Guest Editor
Sunnybrook Health Sciences Centre, University of Toronto, ICES, Ontario Health – Cancer Care Ontario, Toronto, ON M5G 2L7, Canada
Interests: HPB care; upper gastrointestinal (GI) cancers care; GI surgical outcomes and survival; Hepatobiliary surgical outcomes and survival; cancer; clinical guidelines; surgery; health care quality; health economics; quality standards

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Guest Editor
Department of Community Health Sciences, University of Manitoba, Winnipeg MB R3T 2N2, Canada
Interests: cancer; health equity; health services research; mental health

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Guest Editor
Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS B3H 2Y9, Canada
Interests: cancer; health equity; health services research; mental health

Special Issue Information

Dear Colleagues,

From a Western perspective, gastric cancer patients often present at an advanced stage and with a poor prognosis, resulting in limited treatment options. In North America, this leads to a 25% 5-year survival for gastric cancer patients. While surgical resection remains the cornerstone for curative intervention, there have been notable advancements in the treatment of gastric cancer over the past decade that have resulted in more favorable outcomes and prolonged survival.

This Special Edition aims to summarize our current understanding of gastric and gastroesophageal cancer and examine advancements in surgical treatment modalities and outcomes of these diseases.

Dr. Natalie Groce Coburn
Dr. Alyson Mahar
Dr. Stephanie Snow
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastric cancer
  • esophageal cancer
  • gastroesophageal cancer
  • surgical oncology
  • surgical resection
  • surgical intervention
  • cancer outcomes
  • survival outcomes
  • surgery

Published Papers (1 paper)

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Research

14 pages, 1415 KiB  
Article
Laparoscopic versus Open Total Gastrectomy for Locally Advanced Gastric Cancer: Short and Long-Term Results
by Sara Di Carlo, Leandro Siragusa, Alessia Fassari, Enrico Fiori, Francesca La Rovere, Paolo Izzo, Valeria Usai, Giuseppe Cavallaro, Marzia Franceschilli, Sirvjo Dhimolea and Simone Sibio
Curr. Oncol. 2022, 29(11), 8442-8455; https://doi.org/10.3390/curroncol29110665 - 6 Nov 2022
Cited by 4 | Viewed by 1628
Abstract
Background: Laparoscopic gastrectomy for early gastric cancer is widely accepted and routinely performed. However, it is still debated whether the laparoscopic approach is a valid alternative to open gastrectomy in advanced gastric cancer (AGC). The aim of this study is to compare short-and [...] Read more.
Background: Laparoscopic gastrectomy for early gastric cancer is widely accepted and routinely performed. However, it is still debated whether the laparoscopic approach is a valid alternative to open gastrectomy in advanced gastric cancer (AGC). The aim of this study is to compare short-and long-term outcomes of laparoscopic (LG) and open (OG) total gastrectomy with D2 lymphadenectomy in patients with AGC. Methods: A retrospective comparative study was conducted on patients who underwent LG and OG for ACG between January 2015 and December 2021. Primary endpoints were the following: recurrence rate, 3-year disease-free survival, 3-year and 5-year overall survival. Univariate and multivariate analysis was conducted to compare variables influencing outcomes and survival. Results: Ninety-two patients included: fifty-three OG and thirty-nine LG. No difference in morbidity and mortality. LG was associated with lower recurrence rates (OG 22.6% versus LG 12.8%, p = 0.048). No differences in 3-year and 5-year overall survival; 3-year disease-free survival was improved in the LG group on the univariate analysis but not after the multivariate one. LG was associated with longer operative time, lower blood loss and shorter hospital stay. Lymph node yield was higher in LG. Conclusion: LG for AGC seems to provide satisfactory clinical and oncological outcomes in medium volume centers, improved postoperative results and possibly lower recurrence rates. Full article
(This article belongs to the Special Issue Evaluating and Improving Outcomes of Gastric Cancer Surgery)
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