Advanced Technologies for Protein Crystal Optimization and Delivery of Protein Crystals

A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".

Deadline for manuscript submissions: 10 November 2024 | Viewed by 101

Special Issue Editors


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Guest Editor
Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, Notkestrasse 85, c/o DESY, Build. 22a, 22603 Hamburg, Germany
Interests: nucleation in protein crystallization; x-ray crystallography and molecular modeling; multicrystal diffraction; structural infection biology crystallogenesis structure; dynamics of nucleic acids specific plant lectins venom proteomics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, Notkestrasse 85, c/o DESY, Build. 22a, 22603 Hamburg, Germany
Interests: liquid-liquid phase separation; dynamic light scattering; serial crystallography; small angle X-ray; nanotracking analysis; protein crystallography

Special Issue Information

Dear Colleagues,

Over the last years, the establishment and continuous development of Serial Femtosecond Crystallography (SFX) at X-Ray Free Electron Laser (XFEL) radiation sources and the establishment of Serial Crystallography (SX) at high brilliant synchrotron radiation (SR) sources indicate that the methods and procedures applied in modern protein crystallography to collect diffraction data, from utilizing single crystals to well-defined suspensions of crystals, have changed substantially and will continue to do so for the next decade. The latest serial diffraction data collection methods, including corresponding crystal delivery procedures via jets, tape drive or chips, emphasize the increasing efforts towards developing new and efficient procedures to produce protein micro- and nano-crystals, including the challenge of preparing and scoring crystalline suspensions to meet particular crystal delivery methods at SR and XFEL beamlines. This Special Issue aims to summarize and provide insight regarding the latest methods in crystallogenesis to produce micro- and nano-sized crystals, besides conventional single crystal production, in vitro and in vivo. Further, particular methods to characterize crystalline suspensions will be included. In summary, this Special Issue will be of interest for crystal growth experts, as well as for young scientists and scholars interested in the field.

Prof. Dr. Christian Betzel
Dr. Hévila Brognaro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • distinct crystals growth
  • in-vivo crystallization
  • crystal nucleation and liquid dense protein clusters
  • crystal growth for neutron diffraction
  • external electrical and magnetic fields
  • microgravity crystallization
  • mass transport in crystallization
  • in situ analysis of crystals
  • in situ optimization of crystals
  • physicochemical characterization of crystals
  • scoring crystal suspensions
  • instrument and software development
  • crystal delivery for XFEL and synchrotron radiation sources

Published Papers

This special issue is now open for submission.
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